PPARG gene

Aliases: PPAR gamma, PPAR-gamma, PPARγ, Peroxisome proliferator-activated receptor gamma, Pparg, Pparγ
External links: NCBI Gene · Ensembl · GeneCards · UniProt

Evidence from: primary | all sources

Related entities (39)

Subject	Relation	Object	p-value	Evidence
acetaldehyde	regulates	PPARG	—	1
CEU	associated_with	PPARG	—	1
ERK1/2	regulates	PPARG	—	1
ethanol group	regulates	PPARG	—	1
Fgf21	regulates	PPARG	—	1
lipopolysaccharide	regulates	PPARG	—	1
liver injury	regulates	PPARG	—	1
MAPK	regulates	PPARG	—	1
NFKB1	regulates	PPARG	—	1
pioglitazone	targets	PPARG	—	3
PPARG	expressed_in	adipose tissue	—	1
PPARG	associated_with	alcohol dependence	0.03	1
PPARG	associated_with	alcoholic liver disease	—	1
PPARG	associated_with	alcohol withdrawal	0.0095	1
PPARG	risk_factor_for	alcohol withdrawal	—	1
PPARG	associated_with	Alzheimer's disease	—	1
PPARG	protective_against	Alzheimer’s disease	—	1
PPARG	expressed_in	brain	—	1
PPARG	expressed_in	brown adipose tissue	—	1
PPARG	expressed_in	CNS	—	1
PPARG	associated_with	copy number variation	—	1
PPARG	risk_factor_for	diabetes	—	1
PPARG	protective_against	ethanol consumption	—	1
PPARG	protective_against	ethanol preference	—	1
PPARG	protective_against	inflammation	—	1
PPARG	expressed_in	liver	—	1
PPARG	regulates	MCP-1	—	1
PPARG	regulates	NFKB1	—	1
PPARG	interacts_with	RXR	—	1
PPARG	regulates	TNF-α	—	1
PPARG	risk_factor_for	type 2 diabetes	—	1
PPARG	associated_with	withdrawal	—	1
PPARGC1A	interacts_with	PPARG	—	1
PRKCD	regulates	PPARG	—	1
RXR	interacts_with	PPARG	—	1
tagSNP	targets	PPARG	—	1
tesaglitazar	targets	PPARG	—	2
thiazolidinediones	targets	PPARG	—	1
Tlr4	regulates	PPARG	—	1

Mentioned in (34)

Papers in which this entity is mentioned.

Validation of the new EPIC DNA methylation microarray (900K EPIC v2) for high-throughput profiling of the human DNA methylome. (2023)
Genetic Influences on the Developing Young Brain and Risk for Neuropsychiatric Disorders. (2023)
Massively parallel reporter perturbation assays uncover temporal regulatory architecture during neural differentiation. (2022)
Rodent models in placental research. Implications for fetal origins of adult disease. (2022)
Pathogenesis of Alcohol-Associated Fatty Liver: Lessons From Transgenic Mice. (2022)
Integrated Genomic Analysis Identifies Driver Genes and Cisplatin-Resistant Progenitor Phenotype in Pediatric Liver Cancer. (2021)
Evaluating the transcriptional fidelity of cancer models. (2021)
Transcriptomic analyses of gastrulation-stage mouse embryos with differential susceptibility to alcohol. (2021)
Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders. (2021)
Macrophage Polarization States in the Tumor Microenvironment. (2021)
Impact of Proliferator-Activated Receptor γ Gene Polymorphisms on Risk of Schizophrenia: A Case-Control Study and Computational Analyses. (2020)
Programmed increases in LXRα induced by paternal alcohol use enhance offspring metabolic adaptation to high-fat diet induced obesity. (2019)
Hippocampal deficits in neurodevelopmental disorders. (2019)
Neurotrophins in the Brain: Interaction With Alcohol Exposure During Development. (2017)
Genetic studies of alcohol dependence in the context of the addiction cycle. (2017)
A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles. (2017)
Machine learning shows association between genetic variability in and cerebral connectivity in preterm infants. (2017)
Possible relationship between common genetic variation and white matter development in a pilot study of preterm infants. (2016)
Ibuprofen slows migration and inhibits bowel colonization by enteric nervous system precursors in zebrafish, chick and mouse. (2016)
Pioglitazone blocks ethanol induction of microglial activation and immune responses in the hippocampus, cerebellum, and cerebral cortex in a mouse model of fetal alcohol spectrum disorders. (2015)
Peroxisome proliferator-activated receptors α and γ are linked with alcohol consumption in mice and withdrawal and dependence in humans. (2015)
Endocannabinoids are conserved inhibitors of the Hedgehog pathway. (2015)
Cytochrome P450 1B1: An unexpected modulator of liver fatty acid homeostasis. (2015)
Neuroinflammation and M2 microglia: the good, the bad, and the inflamed. (2014)
The PPAR α / γ Agonist, Tesaglitazar, Improves Insulin Mediated Switching of Tissue Glucose and Free Fatty Acid Utilization In Vivo in the Obese Zucker Rat. (2013)
FGF21 promotes metabolic homeostasis via white adipose and leptin in mice. (2012)
Protection of neurons and microglia against ethanol in a mouse model of fetal alcohol spectrum disorders by peroxisome proliferator-activated receptor-γ agonists. (2011)
Genetics of psychiatric disorders methods: molecular approaches. (2010)
Peroxisome proliferator-activated receptor and retinoic x receptor in alcoholic liver disease. (2009)
Marker selection for genetic case-control association studies. (2009)
Effect of in utero and early-life conditions on adult health and disease. (2008)
Heterogeneity in meta-analyses of genome-wide association investigations. (2007)
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. (2007)
Extreme hydrops fetalis and cardiovascular abnormalities in mice lacking a functional Adrenomedullin gene. (2001)

Merged raw entities (2)

All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.

Raw name	Type	Papers	Mentions
pparg	gene	34	109
ppar-gamma	gene	—	—