rimonabant drug
Evidence from:
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Related entities (21)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| rimonabant | associated_with | amygdala | — | 1 |
| rimonabant | interacts_with | cannabinoids | — | 1 |
| rimonabant | targets | CB1 receptor | — | 3 |
| rimonabant | interacts_with | CB1 receptor | — | 2 |
| rimonabant | associated_with | dimethyl sulfoxide | — | 1 |
| rimonabant | regulates | dopamine | — | 1 |
| rimonabant | protective_against | heart rate | — | 1 |
| rimonabant | protective_against | high | — | 1 |
| rimonabant | targets | hippocampus | — | 1 |
| rimonabant | regulates | hypothermia | — | 1 |
| rimonabant | regulates | locomotor activity | — | 1 |
| rimonabant | protective_against | memory | 0.01 | 1 |
| rimonabant | protective_against | nicotine reward | — | 1 |
| rimonabant | protective_against | obesity | — | 1 |
| rimonabant | associated_with | saline | — | 1 |
| rimonabant | protective_against | spatial memory | — | 1 |
| rimonabant | protective_against | subjective effects | — | 1 |
| rimonabant | protective_against | subjective intoxication | — | 1 |
| rimonabant | risk_factor_for | suicide | — | 1 |
| rimonabant | protective_against | tachycardia | — | 1 |
| rimonabant | interacts_with | Δ9-THC | 0.08 | 1 |
Mentioned in (26)
Papers in which this entity is mentioned.
- Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies. (2021)
- Sex-dependent effects of in utero cannabinoid exposure on cortical function. (2018)
- Activity-dependent Signaling and Epigenetic Abnormalities in Mice Exposed to Postnatal Ethanol. (2018)
- An Update on Non-CB, Non-CB Cannabinoid Related G-Protein-Coupled Receptors. (2017)
- CB1 cannabinoid receptor-mediated increases in cyclic AMP accumulation are correlated with reduced Gi/o function. (2016)
- Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB1 and Serotonin 5-HT2A Receptors. (2015)
- CB1-receptor knockout neonatal mice are protected against ethanol-induced impairments of DNMT1, DNMT3A, and DNA methylation. (2015)
- Modelling cognitive affective biases in major depressive disorder using rodents. (2014)
- Distinct pharmacology and metabolism of K2 synthetic cannabinoids compared to Δ(9)-THC: mechanism underlying greater toxicity? (2014)
- Ethanol exposure induces neonatal neurodegeneration by enhancing CB1R Exon1 histone H4K8 acetylation and up-regulating CB1R function causing neurobehavioral abnormalities in adult mice. (2014)
- Synthetic Cannabinoids: Pharmacology, Behavioral Effects, and Abuse Potential. (2014)
- Cannabis controversies: how genetics can inform the study of comorbidity. (2014)
- Moving around the molecule: relationship between chemical structure and in vivo activity of synthetic cannabinoids. (2014)
- Baths salts, spice, and related designer drugs: the science behind the headlines. (2014)
- Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity. (2013)
- Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity. (2012)
- Cannabinoid receptor 1 signaling in embryo neurodevelopment. (2012)
- The cannabinoid receptor CB1 modulates the signaling properties of the lysophosphatidylinositol receptor GPR55. (2012)
- Receptor heteromerization expands the repertoire of cannabinoid signaling in rodent neurons. (2012)
- AT1R-CB₁R heteromerization reveals a new mechanism for the pathogenic properties of angiotensin II. (2011)
- Pharmacological treatment of cannabis dependence. (2011)
- Blockade of nicotine reward and reinstatement by activation of alpha-type peroxisome proliferator-activated receptors. (2011)
- Hippocampal CB(1) receptors mediate the memory impairing effects of Delta(9)-tetrahydrocannabinol. (2009)
- Acute ethanol suppresses glutamatergic neurotransmission through endocannabinoids in hippocampal neurons. (2008)
- Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors augments cAMP accumulation in striatal neurons: evidence for a Gs linkage to the CB1 receptor. (1997)
- Effects of chronic treatment with delta9-tetrahydrocannabinol on cannabinoid-stimulated [35S]GTPgammaS autoradiography in rat brain. (1996)
Merged raw entities (7)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| rimonabant | drug | 16 | 59 |
| sr141716a | drug | 11 | 42 |
| 40 mg daily rimonabant | drug | — | — |
| 40‑mg rimonabant | drug | — | — |
| anti-obesity medication rimonabant | drug | — | — |
| cb1 receptor antagonist rimonabant | drug | — | — |
| rimonant | drug | — | — |