histone drug
Evidence from:
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Related entities (16)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| acetyl-CoA | interacts_with | histone | — | 1 |
| DNA | interacts_with | histone | — | 1 |
| DNA methylation | associated_with | histone | — | 1 |
| DNA methylation | interacts_with | histone | — | 1 |
| enzyme | regulates | histone | — | 1 |
| Epigenetic modifications | targets | histone | — | 1 |
| histone | associated_with | acetylation | — | 1 |
| histone | expressed_in | brain development | — | 1 |
| histone | associated_with | DNA methylation | — | 1 |
| histone | regulates | gene activation | — | 1 |
| histone | regulates | gene expression | — | 2 |
| histone | interacts_with | nucleosome | — | 1 |
| histone | associated_with | phosphorylation | — | 1 |
| histone | regulates | transcription factors | — | 1 |
| nucleosome | associated_with | histone | — | 1 |
| Sir2 | interacts_with | histone | — | 1 |
Mentioned in (51)
Papers in which this entity is mentioned.
- Integrated in vivo combinatorial functional genomics and spatial transcriptomics of tumours to decode genotype-to-phenotype relationships. (2026)
- Alcohol Exposure May Increase Prenatal Choline Needs Through Redirection of Choline into Lipid Synthesis Rather than Methyl Donation. (2025)
- Cell-Free DNA Fragmentomics: The Novel Promising Biomarker. (2023)
- Impact of alcohol exposure on neural development and network formation in human cortical organoids. (2023)
- Epigenetics in Alzheimer's Disease. (2022)
- Epigenetic analysis of cell-free DNA by fragmentomic profiling. (2022)
- CUT&RUNTools: a flexible pipeline for CUT&RUN processing and footprint analysis. (2019)
- Transient Potassium Channels: Therapeutic Targets for Brain Disorders. (2019)
- Epigenetics and depression . (2019)
- Alcohol metabolism contributes to brain histone acetylation. (2019)
- Epigenetic mechanisms in alcohol- and adversity-induced developmental origins of neurobehavioral functioning. (2018)
- Accurate Recycling of Parental Histones Reproduces the Histone Modification Landscape during DNA Replication. (2018)
- Environmental factors influencing the risk of autism. (2017)
- Cell-free DNA Comprises an In Vivo Nucleosome Footprint that Informs Its Tissues-Of-Origin. (2016)
- Oxidative stress signaling to chromatin in health and disease. (2016)
- Two distinct modes for propagation of histone PTMs across the cell cycle. (2015)
- Epigenomics and the structure of the living genome. (2015)
- Post-translational modifications of histones that influence nucleosome dynamics. (2015)
- A comprehensive view of the epigenetic landscape part I: DNA methylation, passive and active DNA demethylation pathways and histone variants. (2015)
- EWS-FLI1 utilizes divergent chromatin remodeling mechanisms to directly activate or repress enhancer elements in Ewing sarcoma. (2014)
- Fetal alcohol spectrum disorders and their transmission through genetic and epigenetic mechanisms. (2014)
- Comprehensive analysis of the transcriptional landscape of the human FMR1 gene reveals two new long noncoding RNAs differentially expressed in Fragile X syndrome and Fragile X-associated tremor/ataxia syndrome. (2014)
- Choline partially prevents the impact of ethanol on the lipid raft dependent functions of l1 cell adhesion molecule. (2014)
- Cancer genome landscapes. (2013)
- Alcohol metabolism and epigenetics changes. (2013)
- In utero alcohol exposure, epigenetic changes, and their consequences. (2013)
- Coordinated cell type-specific epigenetic remodeling in prefrontal cortex begins before birth and continues into early adulthood. (2013)
- Alcohol exposure during development: Impact on the epigenome. (2013)
- Male germline transmits fetal alcohol adverse effect on hypothalamic proopiomelanocortin gene across generations. (2012)
- Early second trimester maternal plasma choline and betaine are related to measures of early cognitive development in term infants. (2012)
- Histone deacetylases (HDAC)-induced histone modifications in the amygdala: a role in rapid tolerance to the anxiolytic effects of ethanol. (2012)
- Annotation of functional variation in personal genomes using RegulomeDB. (2012)
- Regulation of chromatin by histone modifications. (2011)
- Extensive epigenetic reprogramming in human somatic tissues between fetus and adult. (2011)
- Alcohol exposure decreases CREB binding protein expression and histone acetylation in the developing cerebellum. (2011)
- Gene-environment interaction in psychological traits and disorders. (2011)
- Mechanisms and consequences of alternative polyadenylation. (2011)
- Focus on: epigenetics and fetal alcohol spectrum disorders. (2011)
- An integrated ChIP-seq analysis platform with customizable workflows. (2011)
- Epigenetics and psychoneuroimmunology: mechanisms and models. (2011)
- Replicative age induces mitotic recombination in the ribosomal RNA gene cluster of Saccharomyces cerevisiae. (2011)
- Molecular and phenotypic aspects of CHD7 mutation in CHARGE syndrome. (2010)
- Genetics of psychiatric disorders methods: molecular approaches. (2010)
- Molecular maps of the reorganization of genome-nuclear lamina interactions during differentiation. (2010)
- Histone methylation regulates memory formation. (2010)
- The epigenetics of sex differences in the brain. (2009)
- Effect of in utero and early-life conditions on adult health and disease. (2008)
- Genetic and environmental factors in complex neurodevelopmental disorders. (2007)
- Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. (2007)
- Akt phosphorylation of p300 at Ser-1834 is essential for its histone acetyltransferase and transcriptional activity. (2005)
- Environmental programming of stress responses through DNA methylation: life at the interface between a dynamic environment and a fixed genome. (2005)
Merged raw entities (6)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| histones | drug | 20 | 24 |
| histone | drug | 17 | 31 |
| histone h4 | drug | 16 | 24 |
| histone proteins | drug | 10 | 11 |
| epitope-tagged histone | drug | — | — |
| histone 4 | drug | — | — |