ACTB gene

Aliases

ACTB, actin, beta actin, beta-actin, β actin, β-actin

External links

NCBI Gene · Ensembl · GeneCards · UniProt

Related entities (6)

Mentioned in (135)

Papers in which this entity is mentioned.

• LINE-1 retrotransposons mediate cis-acting transcriptional control in human pluripotent stem cells and regulate early brain development. (2025)
• FET fusion oncoproteins disrupt physiologic DNA repair and create a targetable opportunity for ATR inhibitor therapy. (2025)
• Connectome-seq: High-throughput Mapping of Neuronal Connectivity at Single-Synapse Resolution via Barcode Sequencing. (2025)
• Functional analysis of cancer-associated germline risk variants. (2025)
• Synchronized long-read genome, methylome, epigenome and transcriptome profiling resolve a Mendelian condition. (2025)
• Apolipoprotein E intersects with amyloid-β within neurons. (2023)
• Alcohol blunts pregnancy-mediated insulin resistance and reduces fetal brain glucose despite elevated fetal gluconeogenesis, and these changes associate with fetal weight outcomes. (2023)
• Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders. (2021)
• Tead transcription factors differentially regulate cortical development. (2020)
• Neuroprotective Peptide NAPVSIPQ Antagonizes Ethanol Inhibition of L1 Adhesion by Promoting the Dissociation of L1 and Ankyrin-G. (2020)
• Gene Expression in Patient-Derived Neural Progenitors Implicates WNT5A Signaling in the Etiology of Schizophrenia. (2020)
• Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity. (2019)
• Genetic compensation triggered by mutant mRNA degradation. (2019)
• Prenatal nicotine exposure induces depression‑like behavior in adolescent female rats via modulating neurosteroid in the hippocampus. (2019)
• Programmed increases in LXRα induced by paternal alcohol use enhance offspring metabolic adaptation to high-fat diet induced obesity. (2019)
• CYP2A6 is associated with obesity: studies in human samples and a high fat diet mouse model. (2019)
• Maternal circulating miRNAs that predict infant FASD outcomes influence placental maturation. (2019)
• Rapid and reversible suppression of ALT by DAXX in osteosarcoma cells. (2019)
• RNA-Seq Signatures Normalized by mRNA Abundance Allow Absolute Deconvolution of Human Immune Cell Types. (2019)
• Genome-Informed Targeted Therapy for Osteosarcoma. (2019)
• SK Channel Modulates Synaptic Plasticity by Tuning CaMKIIα/β Dynamics. (2019)
• The role and robustness of the Gini coefficient as an unbiased tool for the selection of Gini genes for normalising expression profiling data. (2019)
• Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells. (2018)
• Mutational processes shape the landscape of TP53 mutations in human cancer. (2018)
• Mental Illnesses-Associated Fxr1 and Its Negative Regulator Gsk3β Are Modulators of Anxiety and Glutamatergic Neurotransmission. (2018)
• Lower mRNA Expression in First-Trimester Decidual Tissue from Uncomplicated Term Pregnancies with a Male Fetus. (2018)
• Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector. (2018)
• Activity-dependent Signaling and Epigenetic Abnormalities in Mice Exposed to Postnatal Ethanol. (2018)
• EWS/FLI Confers Tumor Cell Synthetic Lethality to CDK12 Inhibition in Ewing Sarcoma. (2018)
• ChimeRScope: a novel alignment-free algorithm for fusion transcript prediction using paired-end RNA-Seq data. (2017)
• Maternal choline supplementation during murine pregnancy modulates placental markers of inflammation, apoptosis and vascularization in a fetal sex-dependent manner. (2017)
• The genomic landscape of balanced cytogenetic abnormalities associated with human congenital anomalies. (2017)
• Interaction of glycosphingolipids GD3 and GD2 with growth factor receptors maintains breast cancer stem cell phenotype. (2017)
• PGBD5 promotes site-specific oncogenic mutations in human tumors. (2017)
• B lymphocytes and cancer: a love-hate relationship. (2016)
• Cause and Consequence of Tethering a SubTAD to Different Nuclear Compartments. (2016)
• CB1 cannabinoid receptor-mediated increases in cyclic AMP accumulation are correlated with reduced Gi/o function. (2016)
• Association of germline variants in the APOBEC3 region with cancer risk and enrichment with APOBEC-signature mutations in tumors. (2016)
• Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress. (2016)
• Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer. (2016)
• Experience-Dependent Accumulation of N6-Methyladenosine in the Prefrontal Cortex Is Associated with Memory Processes in Mice. (2016)
• Estimating the population abundance of tissue-infiltrating immune and stromal cell populations using gene expression. (2016)
• Glymphatic distribution of CSF-derived apoE into brain is isoform specific and suppressed during sleep deprivation. (2016)
• CB1-receptor knockout neonatal mice are protected against ethanol-induced impairments of DNMT1, DNMT3A, and DNA methylation. (2015)
• Pioglitazone blocks ethanol induction of microglial activation and immune responses in the hippocampus, cerebellum, and cerebral cortex in a mouse model of fetal alcohol spectrum disorders. (2015)
• The cell cycle regulator CCDC6 is a key target of RNA-binding protein EWS. (2015)
• A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis. (2015)
• Ube3a reinstatement identifies distinct developmental windows in a murine Angelman syndrome model. (2015)
• BET inhibitors induce apoptosis through a MYC independent mechanism and synergise with CDK inhibitors to kill osteosarcoma cells. (2015)
• CtBP2 is an independent prognostic marker that promotes GLI1 induced epithelial-mesenchymal transition in hepatocellular carcinoma. (2015)
• RNA imaging. Spatially resolved, highly multiplexed RNA profiling in single cells. (2015)
• MiR-125b protects against ethanol-induced apoptosis in neural crest cells and mouse embryos by targeting Bak 1 and PUMA. (2015)
• Spontaneous ATM Gene Reversion in A-T iPSC to Produce an Isogenic Cell Line. (2015)
• A germline polymorphism of thymine DNA glycosylase induces genomic instability and cellular transformation. (2014)
• GABA-A and NMDA receptor subunit mRNA expression is altered in the caudate but not the putamen of the postmortem brains of alcoholics. (2014)
• The role of BAF (mSWI/SNF) complexes in mammalian neural development. (2014)
• Pre-administration of G9a/GLP inhibitor during synaptogenesis prevents postnatal ethanol-induced LTP deficits and neurobehavioral abnormalities in adult mice. (2014)
• CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma. (2014)
• Expression of ZNF804A in human brain and alterations in schizophrenia, bipolar disorder, and major depressive disorder: a novel transcript fetally regulated by the psychosis risk variant rs1344706. (2014)
• SRF regulates craniofacial development through selective recruitment of MRTF cofactors by PDGF signaling. (2014)
• PVT1 dependence in cancer with MYC copy-number increase. (2014)
• Inhibition of histone H3K9 acetylation by anacardic acid can correct the over-expression of Gata4 in the hearts of fetal mice exposed to alcohol during pregnancy. (2014)
• Ethanol exposure induces neonatal neurodegeneration by enhancing CB1R Exon1 histone H4K8 acetylation and up-regulating CB1R function causing neurobehavioral abnormalities in adult mice. (2014)
• Long noncoding RNA EWSAT1-mediated gene repression facilitates Ewing sarcoma oncogenesis. (2014)
• Ethanol induced acetylation of histone at G9a exon1 and G9a-mediated histone H3 dimethylation leads to neurodegeneration in neonatal mice. (2014)
• Alcohol modulates expression of DNA methyltranferases and methyl CpG-/CpG domain-binding proteins in murine embryonic fibroblasts. (2013)
• Identification of cell-specific patterns of reference gene stability in quantitative reverse-transcriptase polymerase chain reaction studies of embryonic, placental and neural stem models of prenatal ethanol exposure. (2013)
• Ethanol alters gene expression and cell organization during optic vesicle evagination. (2013)
• G9a-mediated histone methylation regulates ethanol-induced neurodegeneration in the neonatal mouse brain. (2013)
• Alcohol exposure in utero increases susceptibility to prostate tumorigenesis in rat offspring. (2013)
• Positively correlated miRNA-mRNA regulatory networks in mouse frontal cortex during early stages of alcohol dependence. (2013)
• LRP1 is critical for the surface distribution and internalization of the NR2B NMDA receptor subtype. (2013)
• Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition. (2013)
• Interleukin-6 (IL-6) receptor/IL-6 fusion protein (Hyper IL-6) effects on the neonatal mouse brain: possible role for IL-6 trans-signaling in brain development and functional neurobehavioral outcomes. (2013)
• Pdgfra protects against ethanol-induced craniofacial defects in a zebrafish model of FASD. (2013)
• Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas. (2013)
• Moderate prenatal alcohol exposure reduces plasticity and alters NMDA receptor subunit composition in the dentate gyrus. (2013)
• Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy. (2013)
• LIN28B promotes growth and tumorigenesis of the intestinal epithelium via Let-7. (2013)
• Nitric oxide rescues thalidomide mediated teratogenicity. (2012)
• Cannabinoid receptor 1 signaling in embryo neurodevelopment. (2012)
• Strain dependent gene expression and neurochemical levels in the brain of zebrafish: focus on a few alcohol related targets. (2012)
• An Inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia. (2012)
• Male germline transmits fetal alcohol adverse effect on hypothalamic proopiomelanocortin gene across generations. (2012)
• Nicotine induces negative energy balance through hypothalamic AMP-activated protein kinase. (2012)
• Growth cone travel in space and time: the cellular ensemble of cytoskeleton, adhesion, and membrane. (2012)
• FGF21 promotes metabolic homeostasis via white adipose and leptin in mice. (2012)
• Chronic shift-lag alters the circadian clock of NK cells and promotes lung cancer growth in rats. (2012)
• miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2. (2012)
• Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs. (2012)
• Skeletogenic fate of zebrafish cranial and trunk neural crest. (2012)
• Chronic intermittent ethanol exposure and its removal induce a different miRNA expression pattern in primary cortical neuronal cultures. (2012)
• Adolescent binge drinking alters adult brain neurotransmitter gene expression, behavior, brain regional volumes, and neurochemistry in mice. (2011)
• A small-molecule smoothened agonist prevents glucocorticoid-induced neonatal cerebellar injury. (2011)
• Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43. (2011)
• Ethanol-induced microphthalmia is not mediated by changes in retinoic acid or sonic hedgehog signaling during retinal neurogenesis. (2011)
• Habenular α5 nicotinic receptor subunit signalling controls nicotine intake. (2011)
• Prenatal choline deficiency does not enhance hippocampal vulnerability after kainic acid-induced seizures in adulthood. (2011)
• Candidate placental biomarkers for intrauterine alcohol exposure. (2011)
• Functional coupling of transcription factor HiNF-P and histone H4 gene expression during pre- and post-natal mouse development. (2011)
• Alcohol exposure decreases CREB binding protein expression and histone acetylation in the developing cerebellum. (2011)
• Effects of ethanol and NAP on cerebellar expression of the neural cell adhesion molecule L1. (2011)
• Neuronal LRP1 knockout in adult mice leads to impaired brain lipid metabolism and progressive, age-dependent synapse loss and neurodegeneration. (2010)
• Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3beta phosphorylation. (2010)
• PDGF function in diverse neural crest cell populations. (2010)
• Condensin complexes regulate mitotic progression and interphase chromatin structure in embryonic stem cells. (2010)
• Fetal alcohol exposure increases mammary tumor susceptibility and alters tumor phenotype in rats. (2010)
• Dyrk1A overexpression inhibits proliferation and induces premature neuronal differentiation of neural progenitor cells. (2010)
• Effects of moderate drinking during pregnancy on placental gene expression. (2010)
• Conserved role of intragenic DNA methylation in regulating alternative promoters. (2010)
• Cocaine exposure modulates dopamine and adenosine signaling in the fetal brain. (2010)
• The opposite effects of acute and chronic alcohol on lipopolysaccharide-induced inflammation are linked to IRAK-M in human monocytes. (2009)
• The opposite effects of acute and chronic alcohol on lipopolysaccharide-induced inflammation are linked to IRAK-M in human monocytes. (2009)
• Microarray analyses reveal regional astrocyte heterogeneity with implications for neurofibromatosis type 1 (NF1)-regulated glial proliferation. (2009)
• Novel neuroprotective mechanisms of memantine: increase in neurotrophic factor release from astroglia and anti-inflammation by preventing microglial activation. (2009)
• Distinct function of 2 chromatin remodeling complexes that share a common subunit, Williams syndrome transcription factor (WSTF). (2009)
• MicroRNA Mirn140 modulates Pdgf signaling during palatogenesis. (2008)
• Ethanol consumption during early pregnancy alters the disposition of tangentially migrating GABAergic interneurons in the fetal cortex. (2008)
• Molecular specification and patterning of progenitor cells in the lateral and medial ganglionic eminences. (2008)
• Fetal alcohol spectrum disorder-associated depression: evidence for reductions in the levels of brain-derived neurotrophic factor in a mouse model. (2008)
• The role of cytoplasmic serine residues of the cell adhesion molecule L1 in neurite outgrowth, endocytosis, and cell migration. (2007)
• Neuroadaptations in human chronic alcoholics: dysregulation of the NF-kappaB system. (2007)
• Maternal immune activation alters fetal brain development through interleukin-6. (2007)
• Defects in embryonic neurogenesis and initial synapse formation in the forebrain of the Ts65Dn mouse model of Down syndrome. (2007)
• Repression of smoothened by patched-dependent (pro-)vitamin D3 secretion. (2006)
• Perlecan, a candidate gene for the CAPB locus, regulates prostate cancer cell growth via the Sonic Hedgehog pathway. (2006)
• Origin of oligodendrocytes in the subventricular zone of the adult brain. (2006)
• Akt phosphorylation of p300 at Ser-1834 is essential for its histone acetyltransferase and transcriptional activity. (2005)
• Identification of a small molecule inhibitor of the hedgehog signaling pathway: effects on basal cell carcinoma-like lesions. (2003)
• Migration of nerve growth cones requires detergent-resistant membranes in a spatially defined and substrate-dependent manner. (2002)
• Antiepileptic drugs and apoptotic neurodegeneration in the developing brain. (2002)
• Mouse Af9 is a controller of embryo patterning, like Mll, whose human homologue fuses with Af9 after chromosomal translocation in leukemia. (2002)
• Myelination is altered in insulin-like growth factor-I null mutant mice. (2002)
• Extreme hydrops fetalis and cardiovascular abnormalities in mice lacking a functional Adrenomedullin gene. (2001)
• Gestational exposure to ethanol suppresses msx2 expression in developing mouse embryos. (1997)

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