IL6 gene

Aliases

IL-6, Il6, interleukin-6

External links

NCBI Gene · Ensembl · GeneCards · UniProt

Related entities (4)

Mentioned in (60)

Papers in which this entity is mentioned.

• DrBioRight 2.0: an LLM-powered bioinformatics chatbot for large-scale cancer functional proteomics analysis. (2025)
• Chromosomal instability as a driver of cancer progression. (2025)
• Oral supplementation of choline attenuates the development of alcohol-related liver disease (ALD). (2024)
• Desmoplastic stromal signatures predict patient outcomes in pancreatic ductal adenocarcinoma. (2023)
• Epsin Nanotherapy Regulates Cholesterol Transport to Fortify Atheroma Regression. (2023)
• Osteoclasts in Osteosarcoma: Mechanisms, Interactions, and Therapeutic Prospects. (2023)
• Rodent models in placental research. Implications for fetal origins of adult disease. (2022)
• Beneficial Effects of Betaine: A Comprehensive Review. (2021)
• Macrophage Polarization States in the Tumor Microenvironment. (2021)
• Immuno-genomic landscape of osteosarcoma. (2020)
• Gene Expression in Patient-Derived Neural Progenitors Implicates WNT5A Signaling in the Etiology of Schizophrenia. (2020)
• Murine Models for the Study of Fetal Alcohol Spectrum Disorders: An Overview. (2020)
• Single-cell RNA landscape of intratumoral heterogeneity and immunosuppressive microenvironment in advanced osteosarcoma. (2020)
• Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations. (2020)
• Relationship of prenatal maternal obesity and diabetes to offspring neurodevelopmental and psychiatric disorders: a narrative review. (2020)
• Peripheral Biomarkers for First-Episode Psychosis-Opportunities from the Neuroinflammatory Hypothesis of Schizophrenia. (2019)
• Prenatal Stress and Maternal Immune Dysregulation in Autism Spectrum Disorders: Potential Points for Intervention. (2019)
• Programmed increases in LXRα induced by paternal alcohol use enhance offspring metabolic adaptation to high-fat diet induced obesity. (2019)
• Ethanol activates immune response in lymphoblastoid cells. (2019)
• The Gene Encoding Protocadherin 9 (PCDH9), a Novel Risk Factor for Major Depressive Disorder. (2018)
• Implications of altered maternal cytokine concentrations on infant outcomes in children with prenatal alcohol exposure. (2018)
• Lower mRNA Expression in First-Trimester Decidual Tissue from Uncomplicated Term Pregnancies with a Male Fetus. (2018)
• PI3K Signaling in Neurons: A Central Node for the Control of Multiple Functions. (2018)
• Diving into the world of alcohol teratogenesis: a review of zebrafish models of fetal alcohol spectrum disorder. (2018)
• Immune Dysfunction and Autoimmunity as Pathological Mechanisms in Autism Spectrum Disorders. (2018)
• Demystifying the cytokine network: Mathematical models point the way. (2017)
• Maternal choline supplementation during murine pregnancy modulates placental markers of inflammation, apoptosis and vascularization in a fetal sex-dependent manner. (2017)
• The effect of alcohol on the differential expression of cluster of differentiation 14 gene, associated pathways, and genetic network. (2017)
• Evidence for an immune signature of prenatal alcohol exposure in female rats. (2016)
• Efficient derivation of microglia-like cells from human pluripotent stem cells. (2016)
• H3K9me3 Inhibition Improves Memory, Promotes Spine Formation, and Increases BDNF Levels in the Aged Hippocampus. (2016)
• Direct Transcriptional Effects of Apolipoprotein E. (2016)
• Fetal sex-based differences in maternal hormones, angiogenic factors, and immune mediators during pregnancy and the postpartum period. (2015)
• A review of the nonpressor and nonantidiuretic actions of the hormone vasopressin. (2015)
• Activation of the FGFR-STAT3 pathway in breast cancer cells induces a hyaluronan-rich microenvironment that licenses tumor formation. (2014)
• The CXCL12/CXCR4 chemokine ligand/receptor axis in cardiovascular disease. (2014)
• Genetic influences on brain developmental trajectories on neuroimaging studies: from infancy to young adulthood. (2014)
• Neonatal cytokines and chemokines and risk of Autism Spectrum Disorder: the Early Markers for Autism (EMA) study: a case-control study. (2014)
• Plasma cytokine profiling in sibling pairs discordant for autism spectrum disorder. (2013)
• Interleukin-6 (IL-6) receptor/IL-6 fusion protein (Hyper IL-6) effects on the neonatal mouse brain: possible role for IL-6 trans-signaling in brain development and functional neurobehavioral outcomes. (2013)
• Differential expression profiles of glycosphingolipids in human breast cancer stem cells vs. cancer non-stem cells. (2013)
• An Inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia. (2012)
• Inflammaging: disturbed interplay between autophagy and inflammasomes. (2012)
• Oncostatin M decreases interleukin-1 β secretion by human synovial fibroblasts and attenuates an acute inflammatory reaction in vivo. (2012)
• Plasma cytokine levels in children with autistic disorder and unrelated siblings. (2012)
• Differential oestrogen receptor binding is associated with clinical outcome in breast cancer. (2012)
• Regulation of cancer progression by β-endorphin neuron. (2012)
• Maternal immune activation by LPS selectively alters specific gene expression profiles of interneuron migration and oxidative stress in the fetus without triggering a fetal immune response. (2012)
• Significant differences in global genomic DNA methylation by gender and race/ethnicity in peripheral blood. (2011)
• Neuronal LRP1 knockout in adult mice leads to impaired brain lipid metabolism and progressive, age-dependent synapse loss and neurodegeneration. (2010)
• Phosphatidylinositol 3-kinase/protein kinase Cdelta activation induces close homolog of adhesion molecule L1 (CHL1) expression in cultured astrocytes. (2010)
• Novel roles for immune molecules in neural development: implications for neurodevelopmental disorders. (2010)
• Cellular metabolic stress: considering how cells respond to nutrient excess. (2010)
• Microarray analyses reveal regional astrocyte heterogeneity with implications for neurofibromatosis type 1 (NF1)-regulated glial proliferation. (2009)
• Peroxisome proliferator-activated receptor and retinoic x receptor in alcoholic liver disease. (2009)
• Neurotoxic effects and biomarkers of lead exposure: a review. (2009)
• Maternal immune activation alters fetal brain development through interleukin-6. (2007)
• Estrogen inhibits GH signaling by suppressing GH-induced JAK2 phosphorylation, an effect mediated by SOCS-2. (2003)
• C-reactive protein: a critical update. (2003)
• Reduced striatal dopamine transporter density in abstinent methamphetamine and methcathinone users: evidence from positron emission tomography studies with [11C]WIN-35,428. (1998)

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