NRXN1 associated_with nicotine

Subject: NRXN1
Relation: associated_with
Object: nicotine
p-value: 0.0001

Evidence from: primary | all sources

Evidence (2 sources)

New insights into the genetics of addiction. (2009) PMID:19238175 cited

neurexin 1 for ND

confidence: 0.90

Association of a single nucleotide polymorphism in neuronal acetylcholine receptor subunit alpha 5 (CHRNA5) with smoking status and with 'pleasurable buzz' during early experimentation with smoking. (2008) PMID:18783506 cited

most significant associations were for SNPs in ... NRXN1 ... showing P-values less than 10−4 ... associated with nicotine dependence in Caucasians

confidence: 0.95