MC4R risk_factor_for obesity
Evidence from:
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Evidence (4 sources)
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
(2010)
PMID:20935630
cited
Each of these genes has been tied to obesity... MC4R ... lead to severe obesity.
confidence: 0.96
Large copy-number variations are enriched in cases with moderate to extreme obesity.
(2010)
PMID:20622171
cited
MC4R has been implicated in monogenic forms of obesity ...
confidence: 0.94
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.
(2009)
PMID:19079261
cited
Disruption in mice of Mc4r ... results in ... obesity
confidence: 0.85
ToppGene Suite for gene list enrichment analysis and candidate gene prioritization.
(2009)
PMID:19465376
cited
Table 2 lists MC4R as a candidate gene for Obesity (Renstrom et al.).
confidence: 0.96