5HTTLPR regulates SLC6A4
Evidence from:
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Evidence (2 sources)
The relationship of 5HTT (SLC6A4) methylation and genotype on mRNA expression and liability to major depression and alcohol dependence in subjects from the Iowa Adoption Studies.
(2008)
PMID:17987668
cited
variance in mRNA and protein production accounted for by the 5HTTLPR is relatively modest (<10%)
confidence: 0.80
The relationship of 5HTT (SLC6A4) methylation and genotype on mRNA expression and liability to major depression and alcohol dependence in subjects from the Iowa Adoption Studies.
(2008)
PMID:17987668
cited
effect size of the 5HTTLPR on mRNA expression
confidence: 0.90