GAD1 associated_with alcohol dependence
Evidence from:
primary |
all sources
Evidence (4 sources)
Ethanol-Associated Changes in Glutamate Reward Neurocircuitry: A Minireview of Clinical and Preclinical Genetic Findings.
(2016)
PMID:26809998
cited
Three polymorphisms of Gad1, but no polymorphisms of Gad2, were significantly associated with alcohol dependence in Han Taiwanese men.
confidence: 0.90
Associations of glutamate decarboxylase genes with initial sensitivity and age-at-onset of alcohol dependence in the Irish Affected Sib Pair Study of Alcohol Dependence.
(2009)
PMID:19111404
cited
Loh et al. (2006) found evidence of association with AD in GAD1 but not GAD2.
confidence: 0.95
Associations of glutamate decarboxylase genes with initial sensitivity and age-at-onset of alcohol dependence in the Irish Affected Sib Pair Study of Alcohol Dependence.
(2009)
PMID:19111404
cited
Case-control association analyses for AD were conducted ... for GAD1 ... genes.
confidence: 0.95
Associations of glutamate decarboxylase genes with initial sensitivity and age-at-onset of alcohol dependence in the Irish Affected Sib Pair Study of Alcohol Dependence.
(2009)
PMID:19111404
cited
The first aim of the present study was to test the association of GAD genes with AD
confidence: 0.95