glutamate interacts_with GRM8

Subject: glutamate
Relation: interacts_with
Object: GRM8
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Ethanol-Associated Changes in Glutamate Reward Neurocircuitry: A Minireview of Clinical and Preclinical Genetic Findings. (2016) PMID:26809998 cited

glutamate interacts with both metabotropic mGlu1–mGlu8 (Grm1–Grm8 = mGluR1–mGluR8)

confidence: 0.96

Genome-wide association study identifies genes that may contribute to risk for developing heroin addiction. (2010) PMID:20520587 cited

Binding of glutamate to mGluR8 inhibits cAMP production.

confidence: 0.96