GABRA2 associated_with alcoholism
Evidence from:
primary |
all sources
Evidence (8 sources)
Clinically relevant genetic biomarkers from the brain in alcoholism with representation on high resolution chromosome ideograms.
(2015)
PMID:25655461
cited
Human genetic studies have identified alcoholism candidate genes ... GABAergic (e.g., GABRA1, GABRA2)
confidence: 0.90
GABA-A and NMDA receptor subunit mRNA expression is altered in the caudate but not the putamen of the postmortem brains of alcoholics.
(2014)
PMID:25538565
cited
The α2β1γ1 gene cluster ... was identified as being influenced by chronic alcohol exposure.
confidence: 0.80
Heritability and molecular-genetic basis of resting EEG activity: a genome-wide association study.
(2014)
PMID:25387704
cited
GABRA2 contains ... a haplotype that is correlated with severity of alcoholism
confidence: 0.93
Impulsiveness and insula activation during reward anticipation are associated with genetic variants in GABRA2 in a family sample enriched for alcoholism.
(2012)
PMID:21483437
cited
GABRA2 variants were previously found to be associated with alcoholism
confidence: 0.90
Impulsiveness and insula activation during reward anticipation are associated with genetic variants in GABRA2 in a family sample enriched for alcoholism.
(2012)
PMID:21483437
cited
variation in GABRA2 has been associated with ... alcoholism
confidence: 0.95
Impulsiveness and insula activation during reward anticipation are associated with genetic variants in GABRA2 in a family sample enriched for alcoholism.
(2012)
PMID:21483437
cited
Genetic variation in GABRA2 ... has been reproducibly associated with both alcoholism
confidence: 0.95
The role of GABA(A) receptors in the acute and chronic effects of ethanol: a decade of progress.
(2009)
PMID:19455309
cited
association of the GABRA2 gene with alcoholism may be complicated by moderate linkage disequilibrium of GABRA2 markers with a functional genetic variation in the adjacent GABRG1 gene
confidence: 0.95
Variants in GABRA2 are strongly associated with alcoholism
confidence: 0.96