alcohol associated_with prefrontal cortex
Evidence from:
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Evidence (4 sources)
Integrated single-cell multiomic profiling of caudate nucleus suggests key mechanisms in alcohol use disorder.
(2025)
PMID:41083468
primary
Chronic alcohol use ... inflammatory signaling ... prefrontal cortex
confidence: 0.90
Polygenic risk for alcohol dependence associates with alcohol consumption, cognitive function and social deprivation in a population-based cohort.
(2016)
PMID:25865819
primary
chronic alcohol consumption is associated with metabolic and morphological changes ... particularly the prefrontal cortex.
confidence: 0.90
Sex/gender differences in brain function and structure in alcohol use: A narrative review of neuroimaging findings over the last 10 years.
(2021)
PMID:32333417
cited
Brain regions such as the PFC ... demonstrate alterations in volume and activation ... as a function of alcohol use (e.g., AUD vs. healthy controls)
confidence: 0.90
prefrontal cortex ... is particularly susceptible to the effects of long-term alcohol abuse
confidence: 0.85