MPEP targets mGluR5

Subject: MPEP
Relation: targets
Object: mGluR5
p-value: —

Evidence from: primary | all sources

Evidence (3 sources)

Ethanol-Associated Changes in Glutamate Reward Neurocircuitry: A Minireview of Clinical and Preclinical Genetic Findings. (2016) PMID:26809998 cited

mGlu5 antagonist 2-methyl-6-(phenylethynyl)pyridine (MPEP)

confidence: 0.96

The role of GABA(A) receptors in the acute and chronic effects of ethanol: a decade of progress. (2009) PMID:19455309 cited

mGluR5 antagonist 2-methyl-6-(2-phenyl-ethynyl)pyridine (MPEP)

confidence: 0.90

Protein kinases and addiction. (2008) PMID:18991950 cited

Systemic administration of the mGluR5 antagonist MPEP.

confidence: 0.95