FTO risk_factor_for obesity
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Evidence (5 sources)
Large-scale genotyping identifies 41 new loci associated with breast cancer risk.
(2013)
PMID:23535729
cited
Two of the newly associated SNPs lie within the TCF7L2 and FTO genes, previously associated with type 2 diabetes and/or obesity through GWAS.
confidence: 0.93
Large copy-number variations are enriched in cases with moderate to extreme obesity.
(2010)
PMID:20622171
cited
FTO represents consistently the strongest gene in many association studies ... for obesity.
confidence: 0.95
Large copy-number variations are enriched in cases with moderate to extreme obesity.
(2010)
PMID:20622171
cited
the OR for FTO is 1.3
confidence: 0.85
FTO locus, the first robustly replicating obesity susceptibility locus
confidence: 0.95
Heterogeneity in meta-analyses of genome-wide association investigations.
(2007)
PMID:17786212
cited
In the case of FTO, it probably reflected the fact it was associated with type 2 diabetes through its effect on the correlated phenotype of obesity.
confidence: 0.93