ADH1B risk_factor_for PAU
Evidence from:
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all sources
Evidence (2 sources)
Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits.
(2020)
PMID:32451486
primary
four significant alcohol dehydrogenase genes ... were associated with expression ... indicating functional consequences of PAU-risk-associated variation.
confidence: 0.70
Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits.
(2020)
PMID:32451486
primary
Ten variants were previously identified ... located in or near the following genes: ADH1B ... and a novel ADH1B variant rs75967634 is GWS for PAU.
confidence: 0.96