SLC6A4 risk_factor_for MD

Subject: SLC6A4
Relation: risk_factor_for
Object: MD
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

The relationship of 5HTT (SLC6A4) methylation and genotype on mRNA expression and liability to major depression and alcohol dependence in subjects from the Iowa Adoption Studies. (2008) PMID:17987668 cited

gene expression at this locus may be associated with altered vulnerability to MD

confidence: 0.80

The relationship of 5HTT (SLC6A4) methylation and genotype on mRNA expression and liability to major depression and alcohol dependence in subjects from the Iowa Adoption Studies. (2008) PMID:17987668 cited

GxE effects at SLC6A4 are particularly pivotal in the development of MD.

confidence: 0.95