Chrna7 associated_with nicotine
Evidence from:
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all sources
Evidence (4 sources)
Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes.
(2012)
PMID:22290489
cited
CHRNA7 SNPs are associated with severity of nicotine dependence in females (Greenbaum et al. 2006).
confidence: 0.95
Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes.
(2012)
PMID:22290489
cited
The role of the α7 subunit, encoded by the CHRNA7 gene, in nicotine dependence ... is not fully understood.
confidence: 0.90
Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans.
(2010)
PMID:20584212
cited
CHRNA7 is nominally associated with nicotine dependence in African-Americans, with little evidence of association in European-Americans.
confidence: 0.80
KO mice for nAChR subunits α3–α9 ... deletion of these genes alters many effects of nicotine.
confidence: 0.90