nicotine interacts_with CHRNA5
Evidence from:
primary |
all sources
Evidence (4 sources)
Nicotine ... binding of the nicotinic acetylcholine receptors ... including CHRNA5
confidence: 0.90
Uncovering hidden variance: pair-wise SNP analysis accounts for additional variance in nicotine dependence.
(2011)
PMID:21079997
cited
biologically active receptors that bind nicotine
confidence: 0.90
Genetic polymorphisms in 15q25 and 19q13 loci, cotinine levels, and risk of lung cancer in EPIC.
(2011)
PMID:21862624
cited
Nicotine binds to the nAChR causing its activation
confidence: 0.85
nicotine exerts its biological function by binding to nAChRs, which are composed of five subunits
confidence: 0.70