ethanol group risk_factor_for alcohol dependence
Evidence from:
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all sources
Evidence (4 sources)
Alcohol dependent individuals are chronically exposed to large quantities of ethanol.
confidence: 0.92
Ethanol-Associated Changes in Glutamate Reward Neurocircuitry: A Minireview of Clinical and Preclinical Genetic Findings.
(2016)
PMID:26809998
cited
central glutamatergic system ... role in alcohol dependence (ethanol affects this system)
confidence: 0.70
Persistent EtOH exposure produces both tolerance and dependence.
confidence: 0.98
Adolescent but not adult rats exhibit ethanol-mediated appetitive second-order conditioning.
(2008)
PMID:18782343
cited
progressing from drug use to abuse and dependence
confidence: 0.95