The association marked by rs16969968 is correlated with genetic variants ... include the α5-α3-β4 nicotinic receptor gene cluster (CHRNA5-CHRNA3-CHRNB4).

confidence: 0.96

Convergence of genetic findings for nicotine dependence and smoking related diseases with chromosome 15q24-25. (2010) PMID:19896728 cited

variant rs16969968, which causes the amino acid change in the α5 nicotinic receptor

confidence: 0.85

Variants in nicotinic acetylcholine receptors alpha5 and alpha3 increase risks to nicotine dependence. (2009) PMID:19132693 cited

rs16969968 is a non-synonymous polymorphism ... of the CHRNA5 gene

confidence: 0.93

Variants in nicotinic acetylcholine receptors alpha5 and alpha3 increase risks to nicotine dependence. (2009) PMID:19132693 cited

Markers with positive reports of association (rs16969968 ...) were included for the interval covering the CHRNA5, CHRNA3, and CHRNB4 genes.

confidence: 0.90

The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans. (2009) PMID:19706762 cited

rs16969968, which causes an amino acid change in CHRNA5

confidence: 0.93

The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans. (2009) PMID:19706762 cited

a nonsynonymous SNP in the alpha5 cholinergic nicotinic receptor subunit gene (CHRNA5)

confidence: 0.90

Association of a single nucleotide polymorphism in neuronal acetylcholine receptor subunit alpha 5 (CHRNA5) with smoking status and with 'pleasurable buzz' during early experimentation with smoking. (2008) PMID:18783506 cited

the alpha 5 polymorphism, rs16969968, a non‑synonymous coding SNP in exon 4 of CHRNA5

confidence: 0.90