ADH1B protective_against alcohol dependence
Evidence from:
primary |
all sources
Evidence (2 sources)
Variations in alcohol-metabolizing enzymes in people of East Indian and African descent from Trinidad and Tobago.
(2007)
PMID:17718398
cited
people with at least one ADH1B*3 allele were significantly less likely to be alcohol dependent
confidence: 0.96
The genetics of alcohol metabolism: role of alcohol dehydrogenase and aldehyde dehydrogenase variants.
(2007)
PMID:17718394
cited
If the man also carries at least one overactive ADH1B*2 allele, the odds ratio declines even further, to 0.05.
confidence: 0.92