ALDH2 risk_factor_for alcoholism
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Evidence (4 sources)
Common liability to addiction and "gateway hypothesis": theoretical, empirical and evolutionary perspective.
(2012)
PMID:22261179
cited
known ... associations for the risk for disorders related to licit compounds (alcoholism ... ALDH ... genes)
confidence: 0.96
known ... aldehyde dehydrogenase 2 (ALDH2) variants in Asians and Jewish Americans
confidence: 0.85
The genetics of alcohol metabolism: role of alcohol dehydrogenase and aldehyde dehydrogenase variants.
(2007)
PMID:17718394
cited
The severe effects of the ALDH2*2 variant on ... alcoholism risk demonstrate ...
confidence: 0.96
The genetics of alcohol metabolism: role of alcohol dehydrogenase and aldehyde dehydrogenase variants.
(2007)
PMID:17718394
cited
ALDH2 ... are the genes most strongly associated with risk for alcoholism.
confidence: 0.95