alcoholism associated_with alcohol dependence
Evidence from:
primary |
all sources
Evidence (7 sources)
Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts.
(2010)
PMID:20468071
primary
Alcoholism was defined by the presence of a DSM-IIIR alcohol dependence diagnosis.
confidence: 0.94
Delta, theta, and alpha event-related oscillations in alcoholics during Go/NoGo task: Neurocognitive deficits in execution, inhibition, and attention processing.
(2016)
PMID:26456730
cited
The alcoholic subjects (Alcohol Dependence as per DSM‑IV criteria) were recruited from alcoholism treatment centers...
confidence: 0.96
GABA-A and NMDA receptor subunit mRNA expression is altered in the caudate but not the putamen of the postmortem brains of alcoholics.
(2014)
PMID:25538565
cited
from alcoholics and individuals without alcohol dependence
confidence: 0.90
GABA-A and NMDA receptor subunit mRNA expression is altered in the caudate but not the putamen of the postmortem brains of alcoholics.
(2014)
PMID:25538565
cited
from alcoholics and individuals without alcohol dependence
confidence: 0.97
Pilot study of iPS-derived neural cells to examine biologic effects of alcohol on human neurons in vitro.
(2012)
PMID:22486492
cited
neural cells derived from alcoholic subjects
confidence: 0.90
Frontally mediated inhibitory processing and white matter microstructure: age and alcoholism effects.
(2011)
PMID:21161189
cited
identify study volunteers who met criteria for alcohol dependence or abuse
confidence: 0.96
Extensive family, twin and adoption study literatures have documented the strong familial transmission of alcoholism... genetic contributions to variation in alcohol dependence (AD), typically accounting for 40–60% of variation in risk.
confidence: 0.90