common variants risk_factor_for alcohol dependence
Evidence from:
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Evidence (3 sources)
Common biological networks underlie genetic risk for alcoholism in African- and European-American populations.
(2013)
PMID:23607416
primary
significant proportion of variance in AD risk can be explained by common SNPs of small effect
confidence: 0.96
Common biological networks underlie genetic risk for alcoholism in African- and European-American populations.
(2013)
PMID:23607416
primary
a skew in the R2 distribution towards more common markers... suggesting an important role for highly common variants in the liability of AD (P = 0.0047 for EA; P = 0.00013 for AA)
confidence: 0.94
Common biological networks underlie genetic risk for alcoholism in African- and European-American populations.
(2013)
PMID:23607416
primary
we aggregated genotypic data ... to test their association to AD, estimating the variance in AD liability accounted by common SNPs
confidence: 0.95