ADH1B associated_with AUDIT-C
Evidence from:
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Evidence (4 sources)
Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.
(2019)
PMID:30940813
primary
including the two most commonly identified alcohol metabolism genes (ADH1B and ADH1C) ... associated with AUDIT-C score
confidence: 0.95
Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.
(2019)
PMID:30940813
primary
rs1229984 in ADH1B shows increased significance for AUDIT-C after BMI correction
confidence: 0.88
Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.
(2019)
PMID:30940813
primary
found a stronger association between age-adjusted mean AUDIT-C score and ADH1B minor allele frequency
confidence: 0.93
Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.
(2019)
PMID:30940813
primary
Meta-analysis ... yielded 13 independent loci, 5 of which were previously associated with a self-reported measure of alcohol consumption: GCKR, KLB, ADH1B, ADH1C, and SLC39A8.
confidence: 0.96