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OPRM1 A118G risk_factor_for Alcohol Use Disorder

Subject
OPRM1 A118G
Relation
risk_factor_for
Object
Alcohol Use Disorder
p-value
Evidence from: primary | all sources

Evidence (4 sources)

Differential sensitivity of human neurons carrying μ opioid receptor (MOR) N40D variants in response to ethanol. (2020) PMID:32561311 primary
the G allele confers genetic vulnerability to alcohol dependence
confidence: 0.90
Differential sensitivity of human neurons carrying μ opioid receptor (MOR) N40D variants in response to ethanol. (2020) PMID:32561311 primary
G minor allele carriers may bestow a genetic susceptibility toward AUDs.
confidence: 0.93
Differential sensitivity of human neurons carrying μ opioid receptor (MOR) N40D variants in response to ethanol. (2020) PMID:32561311 primary
One variant associated with AUDs is ... rs1799971 ...
confidence: 0.90
Differential sensitivity of human neurons carrying μ opioid receptor (MOR) N40D variants in response to ethanol. (2020) PMID:32561311 primary
Extensive work has explored the relationship between OPRM1 A118G and ... alcohol abuse disorders.
confidence: 0.90