neuroticism risk_factor_for mood disorders

Subject: neuroticism
Relation: risk_factor_for
Object: mood disorders
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Neuroticism as a common dimension in the internalizing disorders. (2010) PMID:19903363 cited

neuroticism accounted for 20-45% of comorbidity among various mood and anxiety disorders

confidence: 0.85

Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo. (2009) PMID:19065144 cited

Cases scored much higher on the NEO-FFI neuroticism scale, a known correlate of MDD.

confidence: 0.95