ADH1B risk_factor_for alcohol dependence
Evidence from:
primary |
all sources
Evidence (3 sources)
Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.
(2019)
PMID:30940813
primary
Three previously associated with alcohol dependence—ADH1B, ADH1C, and ADH4.
confidence: 0.97
The largest meta-analysis ... found only one gene associated with the disorder at genome-wide significance, ADH1B.
confidence: 0.96
Genomewide Association Study for Maximum Number of Alcoholic Drinks in European Americans and African Americans.
(2015)
PMID:26036284
primary
All four SNPs in ADH1B were previously shown to be significantly associated with AD.
confidence: 0.90