alcohol self-administration regulates GRM1

Subject: alcohol self-administration
Relation: regulates
Object: GRM1
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Ethanol-Associated Changes in Glutamate Reward Neurocircuitry: A Minireview of Clinical and Preclinical Genetic Findings. (2016) PMID:26809998 cited

operant ethanol self‑administration ... significantly reduced mGlu1 (~20% decrease) expression levels in the AcbSh

confidence: 0.93

Ethanol-Associated Changes in Glutamate Reward Neurocircuitry: A Minireview of Clinical and Preclinical Genetic Findings. (2016) PMID:26809998 cited

operant ethanol self-administration by adult P rats significantly reduced mGlu1 (~20% decrease) expression levels in the AcbSh, relative to ethanol‑naive P rats.

confidence: 0.90