Twin cohort associated_with alcohol
Evidence from:
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Evidence (5 sources)
Genomic regions identified by overlapping clusters of nominally-positive SNPs from genome-wide studies of alcohol and illegal substance dependence.
(2011)
PMID:21818250
primary
including alcohol and illegal drugs from several pharmacological classes
confidence: 0.92
Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117).
(2017)
PMID:28937693
cited
A study of 2877 twin pairs estimated the heritability of alcohol consumption to be 0.43 (95% confidence interval 0.31–0.56).
confidence: 0.95
Role of overlapping genetic and environmental factors in the relationship between early adolescent conduct problems and substance use in young adulthood.
(2016)
PMID:26748618
cited
For level of alcohol consumption, genetic factors also appear to have a moderate influence, with estimates around .50.
confidence: 0.80
Alcohol consumption in men is influenced by qualitatively different genetic factors in adolescence and adulthood.
(2013)
PMID:23282961
cited
use a genetically informative, population-based sample of male twins to determine whether genetic influences on alcohol consumption change
confidence: 0.95
Genetic and environmental factors in complex neurodevelopmental disorders.
(2007)
PMID:19412416
cited
twin studies ... indicated heritability levels of 50-60% in alcohol consumption
confidence: 0.94