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apoE risk_factor_for Alzheimer's disease

Subject
apoE
Relation
risk_factor_for
Object
Alzheimer's disease
p-value
Evidence from: primary | all sources

Evidence (7 sources)

Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer's Disease Phenotypes. (2016) PMID:27622770 cited
disease-associated coding variants ... in the APOE gene
confidence: 0.92
Resting-state network disruption and APOE genotype in Alzheimer's disease: a lagged functional connectivity study. (2012) PMID:23050006 cited
APOE-4 is associated with increased vulnerability to AD, as a genetic risk factor
confidence: 0.96
Resting-state network disruption and APOE genotype in Alzheimer's disease: a lagged functional connectivity study. (2012) PMID:23050006 cited
APOE-4, as a susceptibility factor, are seen in different stages of AD severity
confidence: 0.85
Resting-state network disruption and APOE genotype in Alzheimer's disease: a lagged functional connectivity study. (2012) PMID:23050006 cited
APOE-4, as a risk factor for AD
confidence: 0.95
Managing incidental findings and research results in genomic research involving biobanks and archived data sets. (2012) PMID:22436882 cited
REVEAL Study (focusing on APOE and the risk of Alzheimer’s disease)
confidence: 0.94
Resting-state network disruption and APOE genotype in Alzheimer's disease: a lagged functional connectivity study. (2012) PMID:23050006 cited
APOE-4, a major genetic risk factor for sporadic AD
confidence: 0.95
Molecular insights into the pathogenesis of Alzheimer's disease and its relationship to normal aging. (2011) PMID:22216330 cited
activation of APOE ... early precursors of disease
confidence: 0.80