SLC6A4 interacts_with stressful life events
Evidence from:
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Evidence (5 sources)
Bias in a protocol for a meta-analysis of 5-HTTLPR, stress, and depression.
(2014)
PMID:24939753
cited
interaction between serotonin transporter genotype and life stress
confidence: 0.95
Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis.
(2009)
PMID:19531786
cited
interactive influence between 5-HTTLPR genotype with stressful life events on depression
confidence: 0.85
Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis.
(2009)
PMID:19531786
cited
interaction between genotype and number of life events on risk of depression
confidence: 0.90
Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis.
(2009)
PMID:19531786
cited
Inclusion of the interaction term tests for deviation from a log-additive model of risk ... no interaction between stressful life events and 5-HTTLPR genotype.
confidence: 0.85
Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis.
(2009)
PMID:19531786
cited
a recent critical review of life stressors across these studies... found an interaction effect
confidence: 0.80