GAD1 associated_with alcohol sensitivity
Evidence from:
primary |
all sources
Evidence (3 sources)
Ethanol-Associated Changes in Glutamate Reward Neurocircuitry: A Minireview of Clinical and Preclinical Genetic Findings.
(2016)
PMID:26809998
cited
Two polymorphisms in Gad1 were associated with initial sensitivity to alcohol in the Irish Affected Sib Pair Study of Alcohol Dependence sample.
confidence: 0.85
Associations of glutamate decarboxylase genes with initial sensitivity and age-at-onset of alcohol dependence in the Irish Affected Sib Pair Study of Alcohol Dependence.
(2009)
PMID:19111404
cited
examine evidence that GAD genes are involved with quantitative alcohol-related traits including level of response to ethanol, tolerance, withdrawal and age at onset.
confidence: 0.95
Associations of glutamate decarboxylase genes with initial sensitivity and age-at-onset of alcohol dependence in the Irish Affected Sib Pair Study of Alcohol Dependence.
(2009)
PMID:19111404
cited
they may have impact via their influences on initial sensitivity to ethanol
confidence: 0.90