nicotine interacts_with nucleus accumbens
Evidence from:
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all sources
Evidence (5 sources)
Genetic and environmental contributions to the relationships between brain structure and average lifetime cigarette use.
(2015)
PMID:25690561
cited
important in pathways involved in the processing of the effects of nicotine administration
confidence: 0.90
Structural and functional imaging studies in chronic cannabis users: a systematic review of adolescent and adult findings.
(2013)
PMID:23390554
cited
anticipation activity in these regions may be attenuated by both cannabis and nicotine
confidence: 0.88
COMT Val158Met modulates subjective responses to intravenous nicotine and cognitive performance in abstinent smokers.
(2013)
PMID:23459442
cited
Both the aversive and rewarding effects of nicotine are likely be mediated by DA release in the nucleus accumbens.
confidence: 0.88
Acetylcholine as a neuromodulator: cholinergic signaling shapes nervous system function and behavior.
(2012)
PMID:23040810
cited
increases release of DA from the midbrain projections to the NAc through actions on terminal nAChRs
confidence: 0.90
Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes.
(2012)
PMID:22290489
cited
resulting in dopamine release in the nucleus accumbens
confidence: 0.90