nicotine interacts_with Chrnb4
Evidence from:
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all sources
Evidence (4 sources)
Nicotine ... binding of the nicotinic acetylcholine receptors ... including CHRNB4
confidence: 0.90
Nicotine induces negative energy balance through hypothalamic AMP-activated protein kinase.
(2012)
PMID:22315316
cited
antagonism of α3β4 nicotinic acetylcholine receptors ... demonstrated to be involved in the action of nicotine
confidence: 0.90
Genetic polymorphisms in 15q25 and 19q13 loci, cotinine levels, and risk of lung cancer in EPIC.
(2011)
PMID:21862624
cited
Nicotine binds to the nAChR causing its activation
confidence: 0.85
nicotine exerts its biological function by binding to nAChRs, which are composed of five subunits
confidence: 0.70