Fkbp5 regulates Nr3c1

Subject: Fkbp5
Relation: regulates
Object: Nr3c1
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Evidence for a Link Between Fkbp5/FKBP5, Early Life Social Relations and Alcohol Drinking in Young Adult Rats and Humans. (2017) PMID:27709495 cited

Since FKBP5 is a negative regulator of GR

confidence: 0.93

Evidence for a Link Between Fkbp5/FKBP5, Early Life Social Relations and Alcohol Drinking in Young Adult Rats and Humans. (2017) PMID:27709495 cited

FKBP5 also promotes the internalization of the immature GR complex, thus reducing the GR complex’s activity

confidence: 0.90