ADH1B protective_against alcoholism
Evidence from:
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all sources
Evidence (9 sources)
Review: Pharmacogenetics of alcoholism treatment: Implications of ethnic diversity.
(2017)
PMID:28134463
cited
in Southwest Indians, ADH1 B*3 has shown protective effects against alcoholism
confidence: 0.95
variants ... are protective against alcoholism
confidence: 0.93
The genetics of alcohol dependence: advancing towards systems-based approaches.
(2012)
PMID:22854292
cited
The ADH1B*2 alleles has also been shown to protect against alcoholism in males and females.
confidence: 0.95
The genetics of alcohol metabolism: role of alcohol dehydrogenase and aldehyde dehydrogenase variants.
(2007)
PMID:17718394
cited
Coding variants in both of these genes are strongly protective.
confidence: 0.94
The genetics of alcohol metabolism: role of alcohol dehydrogenase and aldehyde dehydrogenase variants.
(2007)
PMID:17718394
cited
The ADH1B*3 allele also had a protective effect among Southwest California Indians
confidence: 0.96
Variations in alcohol-metabolizing enzymes in people of East Indian and African descent from Trinidad and Tobago.
(2007)
PMID:17718398
cited
the presence of ADH1B*3 in Afro-Trinidadians ... is associated with reduced risk for alcoholism
confidence: 0.96
The genetics of alcohol metabolism: role of alcohol dehydrogenase and aldehyde dehydrogenase variants.
(2007)
PMID:17718394
cited
Among people of Jewish descent ... reduces risk for alcoholism.
confidence: 0.96
The genetics of alcohol metabolism: role of alcohol dehydrogenase and aldehyde dehydrogenase variants.
(2007)
PMID:17718394
cited
the ADH1B*2 allele ... reduces ... risk for alcoholism (Hasin et al. 2002)
confidence: 0.96
The genetics of alcohol metabolism: role of alcohol dehydrogenase and aldehyde dehydrogenase variants.
(2007)
PMID:17718394
cited
...the protective ADH1B*2 allele...
confidence: 0.85