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nicotine interacts_with Chrna4

Subject
nicotine
Relation
interacts_with
Object
Chrna4
p-value
Evidence from: primary | all sources

Evidence (4 sources)

Uncovering hidden variance: pair-wise SNP analysis accounts for additional variance in nicotine dependence. (2011) PMID:21079997 cited
biologically active receptors that bind nicotine
confidence: 0.90
New insights into the genetics of addiction. (2009) PMID:19238175 cited
nicotine exerts its biological function by binding to nAChRs, which are composed of five subunits
confidence: 0.70
Protein kinases and addiction. (2008) PMID:18991950 cited
Acute nicotine treatment desensitizes α4β2 nACh receptors
confidence: 0.85
Nicotinic acetylcholine receptor beta2 subunit gene implicated in a systems-based candidate gene study of smoking cessation. (2008) PMID:18593715 cited
nicotine from a single cigarette nearly completely saturates α4β2 nAChRs
confidence: 0.95