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Goate, Alison M

Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA

TitleYearPMID
Interplay of Genetic Risk Factors and Parent Monitoring in Risk for Nicotine Dependence. 2009 20871796
Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes. 2009 19259974
Nicotine is a selective pharmacological chaperone of acetylcholine receptor number and stoichiometry. Implications for drug discovery. 2009 19280351
Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5. 2009 19443489
The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans. 2009 19706762
Variants weakly correlated with CHRNA5 D398N polymorphism should be considered in transcriptional deregulation at the 15q25 locus associated with lung cancer risk. 2009 19706810
An autosomal linkage scan for cannabis use disorders in the nicotine addiction genetics project. 2008 18519829
A risk allele for nicotine dependence in CHRNA5 is a protective allele for cocaine dependence. 2008 18519132
In search of causal variants: refining disease association signals using cross-population contrasts. 2008 18759969
Linkage scan for quantitative traits identifies new regions of interest for substance dependence in the Collaborative Study on the Genetics of Alcoholism (COGA) sample. 2008 17942244
Systematic biological prioritization after a genome-wide association study: an application to nicotine dependence. 2008 18565990
Variants in nicotinic receptors and risk for nicotine dependence. 2008 18519524
Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs. 2007 17135278
Functional variants in TAS2R38 and TAS2R16 influence alcohol consumption in high-risk families of African-American origin. 2007 17250611
Genetic linkage to chromosome 22q12 for a heavy-smoking quantitative trait in two independent samples. 2007 17436240
Novel genes identified in a high-density genome wide association study for nicotine dependence. 2007 17158188
Functional variant in a bitter-taste receptor (hTAS2R16) influences risk of alcohol dependence. 2006 16385453
Evidence of common and specific genetic effects: association of the muscarinic acetylcholine receptor M2 (CHRM2) gene with alcohol dependence and major depressive syndrome. 2004 15229186
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