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Clarke, Toni-Kim

Division of Psychiatry, University of Edinburgh, Edinburgh, UK

TitleYearPMID
Item-Level Genome-Wide Association Study of the Alcohol Use Disorders Identification Test in Three Population-Based Cohorts. 2022 33985350
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. 2021 34002096
Polygenic contributions to alcohol use and alcohol use disorders across population-based and clinically ascertained samples. 2021 31955720
Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies. 2021 32064741
A large-scale genome-wide association study meta-analysis of cannabis use disorder. 2020 33096046
Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits. 2020 32451486
Minimal phenotyping yields genome-wide association signals of low specificity for major depression. 2020 32231276
Recent Efforts to Dissect the Genetic Basis of Alcohol Use and Abuse. 2020 31733789
Evidence of causal effect of major depression on alcohol dependence: findings from the psychiatric genomics consortium. 2019 30929657
Genome-wide association study identifies 30 loci associated with bipolar disorder. 2019 31043756
Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts. 2019 30336701
Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions. 2019 30718901
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. 2018 29700475
Genome-wide meta-analyses of stratified depression in Generation Scotland and UK Biobank. 2018 29317602
Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders. 2018 30482948
An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype. 2017 28049566
KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference. 2016 27911795
Polygenic risk for alcohol dependence associates with alcohol consumption, cognitive function and social deprivation in a population-based cohort. 2016 25865819
The dopamine receptor D2 (DRD2) SNP rs1076560 is associated with opioid addiction. 2014 24359476
Low frequency genetic variants in the μ-opioid receptor (OPRM1) affect risk for addiction to heroin and cocaine. 2013 23454283
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