Genome-wide association study identifies 30 loci associated with bipolar disorder.
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- Stahl, Eli A; Breen, Gerome; Forstner, Andreas J; McQuillin, Andrew; Ripke, Stephan; Trubetskoy, Vassily; Mattheisen, Manuel; Wang, Yunpeng; Coleman, Jonathan R I; Gaspar, Héléna A; de Leeuw, Christiaan A; Steinberg, Stacy; Pavlides, Jennifer M Whitehead; Trzaskowski, Maciej; Byrne, Enda M; Pers, Tune H; Holmans, Peter A; Richards, Alexander L; Abbott, Liam; Agerbo, Esben; Akil, Huda; Albani, Diego; Alliey-Rodriguez, Ney; Als, Thomas D; Anjorin, Adebayo; Antilla, Verneri; Awasthi, Swapnil; Badner, Judith A; Bækvad-Hansen, Marie; Barchas, Jack D; Bass, Nicholas; Bauer, Michael; Belliveau, Richard; Bergen, Sarah E; Pedersen, Carsten Bøcker; Bøen, Erlend; Boks, Marco P; Boocock, James; Budde, Monika; Bunney, William; Burmeister, Margit; Bybjerg-Grauholm, Jonas; Byerley, William; Casas, Miquel; Cerrato, Felecia; Cervantes, Pablo; Chambert, Kimberly; Charney, Alexander W; Chen, Danfeng; Churchhouse, Claire; Clarke, Toni-Kim; Coryell, William; Craig, David W; Cruceanu, Cristiana; Curtis, David; Czerski, Piotr M; Dale, Anders M; de Jong, Simone; Degenhardt, Franziska; Del-Favero, Jurgen; DePaulo, J Raymond; Djurovic, Srdjan; Dobbyn, Amanda L; Dumont, Ashley; Elvsåshagen, Torbjørn; Escott-Price, Valentina; Fan, Chun Chieh; Fischer, Sascha B; Flickinger, Matthew; Foroud, Tatiana M; Forty, Liz; Frank, Josef; Fraser, Christine; Freimer, Nelson B; Frisén, Louise; Gade, Katrin; Gage, Diane; Garnham, Julie; Giambartolomei, Claudia; Pedersen, Marianne Giørtz; Goldstein, Jaqueline; Gordon, Scott D; Gordon-Smith, Katherine; Green, Elaine K; Green, Melissa J; Greenwood, Tiffany A; Grove, Jakob; Guan, Weihua; Guzman-Parra, José; Hamshere, Marian L; Hautzinger, Martin; Heilbronner, Urs; Herms, Stefan; Hipolito, Maria; Hoffmann, Per; Holland, Dominic; Huckins, Laura; Jamain, Stéphane; Johnson, Jessica S; Juréus, Anders; Kandaswamy, Radhika; Karlsson, Robert; Kennedy, James L; Kittel-Schneider, Sarah; Knowles, James A; Kogevinas, Manolis; Koller, Anna C; Kupka, Ralph; Lavebratt, Catharina; Lawrence, Jacob; Lawson, William B; Leber, Markus; Lee, Phil H; Levy, Shawn E; Li, Jun Z; Liu, Chunyu; Lucae, Susanne; Maaser, Anna; MacIntyre, Donald J; Mahon, Pamela B; Maier, Wolfgang; Martinsson, Lina; McCarroll, Steve; McGuffin, Peter; McInnis, Melvin G; McKay, James D; Medeiros, Helena; Medland, Sarah E; Meng, Fan; Milani, Lili; Montgomery, Grant W; Morris, Derek W; Mühleisen, Thomas W; Mullins, Niamh; Nguyen, Hoang; Nievergelt, Caroline M; Adolfsson, Annelie Nordin; Nwulia, Evaristus A; O'Donovan, Claire; Loohuis, Loes M Olde; Ori, Anil P S; Oruc, Lilijana; Ösby, Urban; Perlis, Roy H; Perry, Amy; Pfennig, Andrea; Potash, James B; Purcell, Shaun M; Regeer, Eline J; Reif, Andreas; Reinbold, Céline S; Rice, John P; Rivas, Fabio; Rivera, Margarita; Roussos, Panos; Ruderfer, Douglas M; Ryu, Euijung; Sánchez-Mora, Cristina; Schatzberg, Alan F; Scheftner, William A; Schork, Nicholas J; Shannon Weickert, Cynthia; Shehktman, Tatyana; Shilling, Paul D; Sigurdsson, Engilbert; Slaney, Claire; Smeland, Olav B; Sobell, Janet L; Søholm Hansen, Christine; Spijker, Anne T; St Clair, David; Steffens, Michael; Strauss, John S; Streit, Fabian; Strohmaier, Jana; Szelinger, Szabolcs; Thompson, Robert C; Thorgeirsson, Thorgeir E; Treutlein, Jens; Vedder, Helmut; Wang, Weiqing; Watson, Stanley J; Weickert, Thomas W; Witt, Stephanie H; Xi, Simon; Xu, Wei; Young, Allan H; Zandi, Peter; Zhang, Peng; Zöllner, Sebastian; eQTLGen Consortium; BIOS Consortium; Adolfsson, Rolf; Agartz, Ingrid; Alda, Martin; Backlund, Lena; Baune, Bernhard T; Bellivier, Frank; Berrettini, Wade H; Biernacka, Joanna M; Blackwood, Douglas H R; Boehnke, Michael; Børglum, Anders D; Corvin, Aiden; Craddock, Nicholas; Daly, Mark J; Dannlowski, Udo; Esko, Tõnu; Etain, Bruno; Frye, Mark; Fullerton, Janice M; Gershon, Elliot S; Gill, Michael; Goes, Fernando; Grigoroiu-Serbanescu, Maria; Hauser, Joanna; Hougaard, David M; Hultman, Christina M; Jones, Ian; Jones, Lisa A; Kahn, René S; Kirov, George; Landén, Mikael; Leboyer, Marion; Lewis, Cathryn M; Li, Qingqin S; Lissowska, Jolanta; Martin, Nicholas G; Mayoral, Fermin; McElroy, Susan L; McIntosh, Andrew M; McMahon, Francis J; Melle, Ingrid; Metspalu, Andres; Mitchell, Philip B; Morken, Gunnar; Mors, Ole; Mortensen, Preben Bo; Müller-Myhsok, Bertram; Myers, Richard M; Neale, Benjamin M; Nimgaonkar, Vishwajit; Nordentoft, Merete; Nöthen, Markus M; O'Donovan, Michael C; Oedegaard, Ketil J; Owen, Michael J; Paciga, Sara A; Pato, Carlos; Pato, Michele T; Posthuma, Danielle; Ramos-Quiroga, Josep Antoni; Ribasés, Marta; Rietschel, Marcella; Rouleau, Guy A; Schalling, Martin; Schofield, Peter R; Schulze, Thomas G; Serretti, Alessandro; Smoller, Jordan W; Stefansson, Hreinn; Stefansson, Kari; Stordal, Eystein; Sullivan, Patrick F; Turecki, Gustavo; Vaaler, Arne E; Vieta, Eduard; Vincent, John B; Werge, Thomas; Nurnberger, John I; Wray, Naomi R; Di Florio, Arianna; Edenberg, Howard J; Cichon, Sven; Ophoff, Roel A; Scott, Laura J; Andreassen, Ole A; Kelsoe, John; Sklar, Pamela; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium
- Year
- 2019
- Journal
- Nature genetics
- PMID
- 31043756
- DOI
- 10.1038/s41588-019-0397-8
- PMCID
- PMC6956732
Bipolar disorder is a highly heritable psychiatric disorder. We performed a genome-wide association study (GWAS) including 20,352 cases and 31,358 controls of European descent, with follow-up analysis of 822 variants with P < 1 × 10 in an additional 9,412 cases and 137,760 controls. Eight of the 19 variants that were genome-wide significant (P < 5 × 10) in the discovery GWAS were not genome-wide significant in the combined analysis, consistent with small effect sizes and limited power but also with genetic heterogeneity. In the combined analysis, 30 loci were genome-wide significant, including 20 newly identified loci. The significant loci contain genes encoding ion channels, neurotransmitter transporters and synaptic components. Pathway analysis revealed nine significantly enriched gene sets, including regulation of insulin secretion and endocannabinoid signaling. Bipolar I disorder is strongly genetically correlated with schizophrenia, driven by psychosis, whereas bipolar II disorder is more strongly correlated with major depressive disorder. These findings address key clinical questions and provide potential biological mechanisms for bipolar disorder.
Manhattan plot for our primary genomewide association analysis of 20,352 cases and 31,358 controls. GWAS -log10P-values are plotted for all SNPs across chromosomes 1-22 (diamonds, green for loci with lead SNP GWAS P < 10−6). Combined GWAS+followup −log10P-values for lead SNPs reaching genome-wide significance in either GWAS or combined analysis (triangles, inverted if GWAS+followup −log10P > GWAS -log10P). Labels correspond to gene symbols previously reported for published loci (black) and the nearest genes for novel loci (blue), at top if GWAS+followup P < 5×10−8. Loci with one-tailed follow-up p > 0.05 (Table 1) have dotted underlined locus names.
Association of BD1 and BD2 subtypes with schizophrenia (SCZ) and major depression (DEPR) polygenic risk scores (PRS). Shown are mean PRS values (1 s.e. error bars), adjusted for study and ancestry covariates and scaled to the PRS mean and sd in control subjects, in BD1 (red) and BD2 (blue) cases, for increasing source GWAS P-value thresholds (increasing grey) as indicated. P-values (italics) test BD1 vs BD2 mean PRS, in logistic regression of case subtype on PRS with covariates. Results are detailed in Supplementary Table 13.
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| Citation | PMID | DOI | Status |
|---|---|---|---|
| 1000 Genomes Project Consortium A global reference for human genetic variation. Nature 526, 68–74 (2015).2643224510.1038/nature15393PMC4750478 | — | — | — |
| AllardyceJ Association Between Schizophrenia-Related Polygenic Liability and the Occurrence and Level of Mood-Incongruent Psychotic Symptoms in Bipolar Disorder. JAMA Psychiatry 75, 28–35 (2018).2916788010.1001/jamapsychiatry.2017.3485PMC5833541 | — | — | — |
| American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders (DSM-5®). (American Psychiatric Pub, 2013). | — | — | — |
| BaumAE A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder. Mol. Psychiatry 13, 197–207 (2008).1748610710.1038/sj.mp.4002012PMC2527618 | — | — | — |
| BenyaminB Childhood intelligence is heritable, highly polygenic and associated with FNBP1L. Mol. Psychiatry 19, 253–258 (2014).2335815610.1038/mp.2012.184PMC3935975 | — | — | — |
| Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium. Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes. Cell 173, 1705–1715.e16 (2018).2990644810.1016/j.cell.2018.05.046PMC6432650 | — | — | — |
| Bulik-SullivanBK LD Score regression distinguishes confounding from polygenicity in genome-wide association studies. Nat. Genet 47, 291–295 (2015).2564263010.1038/ng.3211PMC4495769 | — | — | — |
| BurtonPR Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447, 661–678 (2007).1755430010.1038/nature05911PMC2719288 | — | — | — |
| CamandolaS & MattsonMP Aberrant subcellular neuronal calcium regulation in aging and Alzheimer’s disease. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1813, 965–973 (2011).2095065610.1016/j.bbamcr.2010.10.005PMC3032815 | — | — | — |
| ChangCC Second-generation PLINK: rising to the challenge of larger and richer datasets. Gigascience 4, 7 (2015).2572285210.1186/s13742-015-0047-8PMC4342193 | — | — | — |
| CharneyAW Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder. Transl. Psychiatry 7, e993 (2017).2807241410.1038/tp.2016.242PMC5545718 | — | — | — |
| ChenDT Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder. Mol. Psychiatry 18, 195–205 (2013).2218293510.1038/mp.2011.157 | — | — | — |
| CichonS Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder. Am. J. Hum. Genet 88, 372–381 (2011).2135319410.1016/j.ajhg.2011.01.017PMC3059436 | — | — | — |
| CraddockN & OwenMJ The Kraepelinian dichotomy - going, going… but still not gone. Br. J. Psychiatry 196, 92–95 (2010).2011845010.1192/bjp.bp.109.073429PMC2815936 | — | — | — |
| Cross-Disorder Group of the Psychiatric Genomics Consortium Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat. Genet 45, 984–994 (2013).2393382110.1038/ng.2711PMC3800159 | — | — | — |
| de LeeuwCA, MooijJM, HeskesT & PosthumaD MAGMA: generalized gene-set analysis of GWAS data. PLoS Comput. Biol 11, e1004219 (2015).2588571010.1371/journal.pcbi.1004219PMC4401657 | — | — | — |
| DesfossésJ, StipE, BentalebLA & PotvinS Endocannabinoids and Schizophrenia. Pharmaceuticals 3, 3101–3126 (2010). | — | — | — |
| DuncanL Significant Locus and Metabolic Genetic Correlations Revealed in Genome-Wide Association Study of Anorexia Nervosa. Am. J. Psychiatry appiajp201716121402 (2017).10.1176/appi.ajp.2017.16121402PMC558121728494655 | — | — | — |
| EdvardsenJ Heritability of bipolar spectrum disorders. Unity or heterogeneity? J. Affect. Disord 106, 229–240 (2008).1769238910.1016/j.jad.2007.07.001 | — | — | — |
| EuesdenJ, LewisCM & O’ReillyPF PRSice: Polygenic Risk Score software. Bioinformatics 31, 1466–1468 (2015).2555032610.1093/bioinformatics/btu848PMC4410663 | — | — | — |
| FerrariAJ The prevalence and burden of bipolar disorder: findings from the Global Burden of Disease Study 2013. Bipolar Disord. 18, 440–450 (2016).2756628610.1111/bdi.12423 | — | — | — |
| FerreiraMAR Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nat. Genet 40, 1056–1058 (2008).1871136510.1038/ng.209PMC2703780 | — | — | — |
| FinucaneH Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types. doi:10.1101/103069PMC589679529632380 | — | — | — |
| FinucaneHK Partitioning heritability by functional annotation using genome-wide association summary statistics. Nat. Genet 47, 1228–1235 (2015).2641467810.1038/ng.3404PMC4626285 | — | — | — |
| GaleCR Pleiotropy between neuroticism and physical and mental health: findings from 108 038 men and women in UK Biobank. Transl. Psychiatry 6, e791 (2016).2711512210.1038/tp.2016.56PMC4872414 | — | — | — |
| GaoX, StarmerJ & MartinER A multiple testing correction method for genetic association studies using correlated single nucleotide polymorphisms. Genet. Epidemiol 32, 361–369 (2008).1827102910.1002/gepi.20310 | — | — | — |
| GasparHA & BreenG Pathways analyses of schizophrenia GWAS focusing on known and novel drug targets. Biorxiv (2017). doi:10.1101/091264 | — | — | — |
| GoesFS Genome-wide association of mood-incongruent psychotic bipolar disorder. Transl. Psychiatry 2, e180 (2012).2309298410.1038/tp.2012.106PMC3565814 | — | — | — |
| GoesFS Genome-wide association study of schizophrenia in Ashkenazi Jews. Am. J. Med. Genet. B Neuropsychiatr. Genet 168, 649–659 (2015).2619876410.1002/ajmg.b.32349 | — | — | — |
| GrattenJ, WrayNR, KellerMC & VisscherPM Large-scale genomics unveils the genetic architecture of psychiatric disorders. Nat. Neurosci 17, 782–790 (2014).2486604410.1038/nn.3708PMC4112149 | — | — | — |
| GreenEK Association at SYNE1 in both bipolar disorder and recurrent major depression. Mol. Psychiatry 18, 614–617 (2013).2256578110.1038/mp.2012.48 | — | — | — |
| GreenEK Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample. Mol. Psychiatry 18, 1302–1307 (2013).2307007510.1038/mp.2012.142PMC3971368 | — | — | — |
| HollandD Beyond SNP Heritability: Polygenicity and Discoverability Estimated for Multiple Phenotypes with a Univariate Gaussian Mixture Model. bioRxiv 133132 (2018). doi:10.1101/133132PMC727210132427991 | — | — | — |
| HouL Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder. Hum. Mol. Genet 25, 3383–3394 (2016).2732976010.1093/hmg/ddw181PMC5179929 | — | — | — |
| IkedaM A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder. Mol. Psychiatry (2017). doi:10.1038/mp.2016.259PMC582244828115744 | — | — | — |
| LeeS-H, ZabolotnyJM, HuangH, LeeH & KimY-B Insulin in the nervous system and the mind: Functions in metabolism, memory, and mood. Mol Metab 5, 589–601 (2016).2765639710.1016/j.molmet.2016.06.011PMC5021669 | — | — | — |
| LeeSH Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat. Genet 45, 984–994 (2013).2393382110.1038/ng.2711PMC3800159 | — | — | — |
| LeeSH, GoddardME, WrayNR & VisscherPM A better coefficient of determination for genetic profile analysis. Genet. Epidemiol 36, 214–224 (2012).2271493510.1002/gepi.21614 | — | — | — |
| LichtensteinP Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study. Lancet 373, 234–239 (2009).1915070410.1016/S0140-6736(09)60072-6PMC3879718 | — | — | — |
| MacArthurJ The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog). Nucleic Acids Res. 45, D896–D901 (2017).2789967010.1093/nar/gkw1133PMC5210590 | — | — | — |
| MacCabeJH Excellent school performance at age 16 and risk of adult bipolar disorder: national cohort study. Br. J. Psychiatry 196, 109–115 (2010).2011845410.1192/bjp.bp.108.060368 | — | — | — |
| McGuffinP The heritability of bipolar affective disorder and the genetic relationship to unipolar depression. Arch. Gen. Psychiatry 60, 497–502 (2003).1274287110.1001/archpsyc.60.5.497 | — | — | — |
| McIntyreRS A randomized, double-blind, controlled trial evaluating the effect of intranasal insulin on neurocognitive function in euthymic patients with bipolar disorder. Bipolar Disord. 14, 697–706 (2012).2310722010.1111/bdi.12006 | — | — | — |
| MertensJ Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder. Nature 527, 95–99 (2015).2652452710.1038/nature15526PMC4742055 | — | — | — |
| MühleisenTW Genome-wide association study reveals two new risk loci for bipolar disorder. Nat. Commun 5, 3339 (2014).2461889110.1038/ncomms4339 | — | — | — |
| OkbayA Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nat. Genet (2016). doi:10.1038/ng.3552PMC488415227089181 | — | — | — |
| OkbayA Genome-wide association study identifies 74 loci associated with educational attainment. Nature 533, 539–542 (2016).2722512910.1038/nature17671PMC4883595 | — | — | — |
| OlierI, VellidoA & GiraldoJ Kernel generative topographic mapping. in ESANN 2010, 481–486 (2010). | — | — | — |
| OtowaT Meta-analysis of genome-wide association studies of anxiety disorders. Mol. Psychiatry 21, 1391–1399 (2016).2675495410.1038/mp.2015.197PMC4940340 | — | — | — |
| O’DushlaineC Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. Nat. Neurosci 18, 199–209 (2015).2559922310.1038/nn.3922PMC4378867 | — | — | — |
| PalmerC & Pe’erI Statistical Correction of the Winner9s Curse Explains Replication Variability in Quantitative Trait Genome-Wide Association Studies. bioRxiv 104786 (2017).10.1371/journal.pgen.1006916PMC553639428715421 | — | — | — |
| PalmerC & Pe’erI Statistical correction of the Winner’s Curse explains replication variability in quantitative trait genome-wide association studies. PLoS Genet. 13, e1006916 (2017).2871542110.1371/journal.pgen.1006916PMC5536394 | — | — | — |
| PavlidesJMW Predicting gene targets from integrative analyses of summary data from GWAS and eQTL studies for 28 human complex traits. Genome Med. 8, 84 (2016).2750638510.1186/s13073-016-0338-4PMC4979185 | — | — | — |
| PersTH Biological interpretation of genome-wide association studies using predicted gene functions. Nat. Commun 6, 5890 (2015).2559783010.1038/ncomms6890PMC4420238 | — | — | — |
| PurcellS PLINK: a tool set for whole-genome association and population-based linkage analyses. Am. J. Hum. Genet 81, 559–575 (2007).1770190110.1086/519795PMC1950838 | — | — | — |
| QiT Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood. Nat. Commun 9, 2282 (2018).2989197610.1038/s41467-018-04558-1PMC5995828 | — | — | — |
| RietveldCA GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science 340, 1467–1471 (2013).2372242410.1126/science.1235488PMC3751588 | — | — | — |
| RipkeS Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat. Genet 45, 1150–1159 (2013).2397487210.1038/ng.2742PMC3827979 | — | — | — |
| RipkeS Ricopili: a tool for visualizing regions of interest in select GWAS data sets. (2014). | — | — | — |
| Schizophrenia Working Group of the Psychiatric Genomics Consortium. Biological insights from 108 schizophrenia-associated genetic loci. Nature 511, 421–427 (2014).2505606110.1038/nature13595PMC4112379 | — | — | — |
| SchulzeTG Two variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorder. Mol. Psychiatry 14, 487–491 (2009).1908873910.1038/mp.2008.134PMC2793269 | — | — | — |
| ScottLJ Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry. Proc. Natl. Acad. Sci. U. S. A 106, 7501–7506 (2009).1941692110.1073/pnas.0813386106PMC2678639 | — | — | — |
| SerraG & FrattaW A possible role for the endocannabinoid system in the neurobiology of depression. Clin. Pract. Epidemiol. Ment. Health 3, 25 (2007).1802143910.1186/1745-0179-3-25PMC2169225 | — | — | — |
| SimonsenC Neurocognitive dysfunction in bipolar and schizophrenia spectrum disorders depends on history of psychosis rather than diagnostic group. Schizophr. Bull 37, 73–83 (2011).1944361610.1093/schbul/sbp034PMC3004191 | — | — | — |
| SklarP Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. Nat. Genet 43, 977–U162 (2011).2192697210.1038/ng.943PMC3637176 | — | — | — |
| SklarP Whole-genome association study of bipolar disorder. Mol. Psychiatry 13, 558–569 (2008).1831746810.1038/sj.mp.4002151PMC3777816 | — | — | — |
| SmithEN Genome-wide association study of bipolar disorder in European American and African American individuals. Mol. Psychiatry 14, 755–763 (2009).1948804410.1038/mp.2009.43PMC3035981 | — | — | — |
| SniekersS Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence. Nat. Genet 49, 1107–1112 (2017).2853067310.1038/ng.3869PMC5665562 | — | — | — |
| VreekerA High educational performance is a distinctive feature of bipolar disorder: a study on cognition in bipolar disorder, schizophrenia patients, relatives and controls. Psychol. Med 46, 807–818 (2016).2662161610.1017/S0033291715002299PMC5824688 | — | — | — |
| World Health Organization. The ICD-10 Classification of Mental and Behavioural Disorders: Clinical Descriptions and Diagnostic Guidelines. (World Health Organization, 1992). | — | — | — |
| WrayNR & SullivanPF Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. bioRxiv (2017).10.1038/s41588-018-0090-3PMC593432629700475 | — | — | — |
| YangC-P Comprehensive integrative analyses identify GLT8D1 and CSNK2B as schizophrenia risk genes. Nat. Commun 9, 838 (2018).2948353310.1038/s41467-018-03247-3PMC5826945 | — | — | — |
| ZamberlettiE, RubinoT & ParolaroD The endocannabinoid system and schizophrenia: integration of evidence. Curr. Pharm. Des 18, 4980–4990 (2012).2271615910.2174/138161212802884744 | — | — | — |
| ZhengJ LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis. Bioinformatics 33, 272–279 (2017).2766350210.1093/bioinformatics/btw613PMC5542030 | — | — | — |
| ZhongH & PrenticeRL Bias-reduced estimators and confidence intervals for odds ratios in genome-wide association studies. Biostatistics 9, 621–634 (2008).1831005910.1093/biostatistics/kxn001PMC2536726 | — | — | — |
| ZhuZ Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets. Nat. Genet 48, 481–487 (2016).2701911010.1038/ng.3538 | — | — | — |
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| Role of onset polarity in the risk of parental severe mental disorders among offspring with bipolar disorder. | Li DJ et al. | — | 2026 | → |
| "SHANK3 deficiency alters early progenitor dynamics and reveals shared pathways with neurodegeneration". | Varella-Branco E et al. | — | 2026 | → |
| Spatiotemporal brain transcriptomics reveal risk gene hot-spots in major neuropsychiatric disorders. | Liu W et al. | — | 2026 | → |
| The genetic relationships between post-traumatic stress disorder and its corresponding neural circuit structures. | Gong Q et al. | — | 2026 | → |
| Whole-genome sequence-based association analysis of African American individuals with bipolar disorder and schizophrenia. | Li R et al. | — | 2026 | → |
| A bipolar disorder-associated missense variant alters adenylyl cyclase 2 activity and promotes mania-like behavior. | Sen P et al. | — | 2025 | → |
| A Brief Introduction to Genomics and Single-cell Analysis for Psychiatric Disorders. | Nishioka M | — | 2025 | → |
| A computational framework for defining and validating reproducible phenotyping algorithms of 313 diseases in the UK Biobank. | Torralbo A et al. | — | 2025 | → |
| A Critical Overview of the Validity of the Current Concept of Bipolar Disorder. | Martino DJ et al. | — | 2025 | → |
| A cross-tissue transcriptome-wide association study identifies new susceptibility genes for insomnia. | Li L et al. | — | 2025 | → |
| Advances in discerning the mechanisms underlying depression and resiliency: relation to the neurobiology of stress and the effects of antidepressants. | Gold PW et al. | — | 2025 | → |
| A map of enhancer regions in primary human neural progenitor cells using capture STARR-seq. | Gaynor-Gillett SC et al. | — | 2025 | → |
| Analyses of GWAS and Sub-Threshold Loci Lead to the Discovery of Dendrite Development and Morphology Dysfunction Underlying Schizophrenia Genetic Risk. | Chen R et al. | — | 2025 | → |
| A plasma proteome-mediated Mendelian randomization study reveals the impact of rheumatoid arthritis on mental disorders in a European population. | Wang J et al. | — | 2025 | → |
| Association between frailty and common psychiatric disorders: A bidirectional Mendelian randomization study. | Xiao H et al. | — | 2025 | → |
| Association between keloid and mental disorders: perspective from genetic evidence. | Zhan Y et al. | — | 2025 | → |
| Association Between Socioeconomic Status and Neuropsychiatric Symptoms in the UK Biobank: The Moderating Role of Sociability. | Xiao J et al. | — | 2025 | → |
| Associations of Rare Variants in the <i>AKAP11</i> Gene with Bipolar Disorder in Chinese Population. | Zhang Y et al. | — | 2025 | → |
| Atlas of Proteomic signatures of brain structure and its links to brain disorders. | Ren P et al. | — | 2025 | → |
| Bidirectional causal associations between plasma metabolites and bipolar disorder. | Zhao Q et al. | — | 2025 | → |
| Bipolar Disorders in Saudi Arabia: What Do We Know So Far? | Almadani AH et al. | — | 2025 | → |
| Bipolar II disorder: a state-of-the-art review. | Berk M et al. | — | 2025 | → |
| Blood lipid profiles and mood disorders: A principal component analysis of UK Biobank data reveals distinct associations with depression and bipolar disorder. | Liu X et al. | — | 2025 | → |
| Brain region and cell type-specific DNA methylation profiles in association with ADHD. | Meijer M et al. | — | 2025 | → |
| Causal relationship between mental disorders and abdominal aortic aneurysm: Insights from the genetic perspective. | Deng MG et al. | — | 2025 | → |
| Causal Relationships Between Retinal Diseases and Psychiatric Disorders Have Implications for Precision Psychiatry. | Zhang Z et al. | — | 2025 | → |
| Characterizing Genetic-Predisposed Proteins Involving Insomnia by Integrating Genome-Wide Association Study Summary Statistics. | Long J et al. | — | 2025 | → |
| Chromatin accessibility during human first-trimester neurodevelopment. | Mannens CCA et al. | — | 2025 | → |
| Comparing Alzheimer's genes in African, European, and Amerindian induced pluripotent stem cell-derived microglia. | Moura S et al. | — | 2025 | → |
| Copy number variations in RNF216 and postsynaptic membrane-associated genes are associated with bipolar disorder: a case-control study in the Japanese population. | Nakatochi M et al. | — | 2025 | → |
| Deciphering the shared genetic architecture between bipolar disorder and body mass index. | Ma H et al. | — | 2025 | → |
| Dietary intake and five types of mental disorders: a bidirectional Mendelian randomization study. | Zhang Y et al. | — | 2025 | → |
| Differential Association of the <i>DISC1</i> Interactome in Hallucinations and Delusions. | Gutiérrez-RodrÃguez A et al. | — | 2025 | → |
| Dissecting causal relationships between cortical morphology and neuropsychiatric disorders: a bidirectional Mendelian randomization study. | Lin BD et al. | — | 2025 | → |
| Dissociable genetic influences on eye movements during abstract versus naturalistic social scene viewing in infancy. | Portugal AM et al. | — | 2025 | → |
| Dysfunction of the rostral lateral septum GABAergic neurons induces mania-like behavior in male mice. | Zhou Y et al. | — | 2025 | → |
| Enhancing the discriminatory power of polygenic scores for ADHD and autism in clinical and non-clinical samples. | Li JJ et al. | — | 2025 | → |
| Evaluation of retinal layer thickness in patients with bipolar disorder, their relatives, and healthy controls using optical coherence tomography. | Seven E et al. | — | 2025 | → |
| Exploring the genetic landscape of the brain-heart axis: A comprehensive analysis of pleiotropic effects between heart disease and psychiatric disorders. | Song Q et al. | — | 2025 | → |
| Extracellular Vesicles for Disease Treatment. | Wang F et al. | — | 2025 | → |
| Family study of bipolar disorder with comorbid anxiety disorder points to <i>THSD7A</i> with possible role of parent-of-origin effect. | Maki H et al. | — | 2025 | → |
| Fine-mapping genomic loci refines bipolar disorder risk genes. | Koromina M et al. | — | 2025 | → |
| From Mind to Liver: Exploring the Causal Relationship Between Anxiety Disorders and Non-Alcoholic Fatty Liver Disease Through Mendelian Randomization and UK Biobank Validation. | Song H et al. | — | 2025 | → |
| Genetic analysis of psychosis Biotypes: shared Ancestry-adjusted polygenic risk and unique genomic associations. | Xia C et al. | — | 2025 | → |
| Genetic and Environmental Effects on Parent-Rated Adaptive Behaviour in Infancy. | Halkola H et al. | — | 2025 | → |
| Genetic factors predicting risk of mood disorders in adolescents. | Gangaraju SH et al. | — | 2025 | → |
| Genome-wide association study unravels mechanisms of brain glymphatic activity. | Huang SY et al. | — | 2025 | → |
| Genomic and transcriptomic analyses reveal the genetic basis of leg diseases in laying hens. | Guo M et al. | — | 2025 | → |
| Genomics of Bipolar Disorder: What the Clinician Needs to Know. | McQuillin A et al. | — | 2025 | → |
| Genomics yields biological and phenotypic insights into bipolar disorder. | O'Connell KS et al. | — | 2025 | → |
| Heterogeneity analysis provides evidence for a genetically homogeneous subtype of bipolar-disorder. | McGrouther CC et al. | — | 2025 | → |
| Identification of candidate genes associated with bipolar disorder by whole-exome sequencing of a Chinese multi-affected pedigree. | Wang Y et al. | — | 2025 | → |
| Identification of Mood Disorders Causal Genes by Integrating the Brain Proteome and Transcriptome. | Zhu RK et al. | — | 2025 | → |
| Identifying genetic differences between bipolar disorder and major depression through multiple genome-wide association analyses. | Panagiotaropoulou G et al. | — | 2025 | → |
| Improving Machine Learning Prediction of ADHD Using Gene Set Polygenic Risk Scores and Risk Scores From Genetically Correlated Phenotypes. | Barnett EJ et al. | — | 2025 | → |
| Increased somatic mosaicism in autosomal and X chromosomes for suicide death. | Otsuka I et al. | — | 2025 | → |
| Independent inheritance of cognition and bipolar disorder in a family sample. | D'Amico A et al. | — | 2025 | → |
| Interaction of early life stress and NAD + /SIRT1 pathway genetic risk promotes depression. | Torok D et al. | — | 2025 | → |
| Limbic-Sensorimotor Tug of War for the Hippocampus: Dynamic Functional Connectivity as a Transdiagnostic Vulnerability Marker in Offspring of Patients With Emotion Dysregulation. | Saccaro LF et al. | — | 2025 | → |
| Linking Genome-Wide Association Studies to Pharmacological Treatments for Psychiatric Disorders. | Arnatkeviciute A et al. | — | 2025 | → |
| Linking Mitochondrial Dysfunction, Neurotransmitter, and Neural Network Abnormalities and Mania: Elucidating Neurobiological Mechanisms of the Therapeutic Effect of the Ketogenic Diet in Bipolar Disorder. | Freyberg Z et al. | — | 2025 | → |
| Lithium partially rescues gene expression and enhancer activity from heterozygous knockout of AKAP11 while inducing novel differential changes. | Farhangdoost N et al. | — | 2025 | → |
| Lithium restores inhibitory function and neuronal excitability through GSK-3β inhibition in a bipolar disorder-associated Ank3 variant mouse model. | Caballero-Florán RN et al. | — | 2025 | → |
| Long-read sequencing reveals the RNA isoform repertoire of neuropsychiatric risk genes in human brain. | De Paoli-Iseppi R et al. | — | 2025 | → |
| Mediating Role of Trauma Connecting Psychiatric Family History and Adolescent Mental Health. | Chaiyachati BH et al. | — | 2025 | → |
| Mendelian Randomization Analyses Support Causal Relationships Between Psychiatric Disorders and Risk of Urinary Tract Infections. | Ke M et al. | — | 2025 | → |
| Mendelian Randomization Analysis of the Possible Causal Relationships Between Neurodevelopment-Related Proteins and Bipolar Disorder. | Li Y et al. | — | 2025 | → |
| Mendelian randomization analysis unveiling the genetic connection: How psychiatric disorders heighten cancer risk. | Wang J et al. | — | 2025 | → |
| Mental health and sleep correlates of self-reported outdoor daylight exposure in over 13,000 adults with depression. | Crouse JJ et al. | — | 2025 | → |
| MicroRNAs as potential diagnostic biomarkers for bipolar disorder. | Martinez B et al. | — | 2025 | → |
| MIR124 polygenic risk and functional connectivity of the striatum in patients with bipolar disorder: mediation by childhood trauma. | Zhong S et al. | — | 2025 | → |
| Mitochondrial translation impairment-triggered neuroinflammation mediates fluoride-induced cognitive deficits. | Liu W et al. | — | 2025 | → |
| Multitrait Analysis to Decipher the Intertwined Genetic Architecture of Neuroanatomical Phenotypes and Psychiatric Disorders. | Auvergne A et al. | — | 2025 | → |
| Network localization of genetic risk for schizophrenia and bipolar disorder. | Yao S et al. | — | 2025 | → |
| Neurocognitive correlates of polygenic risk for bipolar disorder among youth with and without bipolar disorder. | Jiang X et al. | — | 2025 | → |
| Neuroglia in mood disorders. | Snijders GJLJ et al. | — | 2025 | → |
| Neuroimaging changes in pre-treatment and post-treatment patients with bipolar disorder and their relationship with genetic characteristics. | Zhang C et al. | — | 2025 | → |
| Neuroimaging Changes in the Sensorimotor Network and Visual Network in Bipolar Disorder and Their Relationship with Genetic Characteristics. | Zhang C et al. | — | 2025 | → |
| New Genomics Discoveries Across the Bipolar Disorder Spectrum Implicate Neurobiological and Developmental Pathways. | O'Connell KS et al. | — | 2025 | → |
| Polygenic and Polyenvironment Interplay in Schizophrenia-Spectrum Disorder and Affective Psychosis; the EUGEI First Episode Study. | Rodriguez V et al. | — | 2025 | → |
| Polygenic architecture of brain structure and function, behaviors, and psychopathologies in children. | Joo YY et al. | — | 2025 | → |
| Polygenic scores and symptom severity change after internet-delivered cognitive behaviour therapy for depression and anxiety. | Bäckman J et al. | — | 2025 | → |
| POU3F2 regulates canonical Wnt signalling via SOX13 and ADNP to expand the neural progenitor population. | Benoit CR et al. | — | 2025 | → |
| Predicting mental health disorder onsets with Fibonacci sequencing: A genetic and epigenetic perspective. | Sacco RG et al. | — | 2025 | → |
| Preliminary exploration of potential biomarkers for heart failure and bipolar disorder: an exploratory study based on bioinformatics. | Zhang W et al. | — | 2025 | → |
| Rare loss-of-function variants in HECTD2 and AKAP11 confer risk of bipolar disorder. | Thorgeirsson TE et al. | — | 2025 | → |
| Recent advances on the physiological and pathophysiological roles of polyunsaturated fatty acids and their biosynthetic pathway. | Lee-Okada HC et al. | — | 2025 | → |
| Roluperidone monotherapy, a treatment for negative symptoms in schizophrenia. | Davidson M et al. | — | 2025 | → |
| SETD1A regulates psychiatric gene networks involved in genomic stability and synaptic function in rare and sporadic schizophrenia. | Sawada T et al. | — | 2025 | → |
| Shared Overall Topological Impairments of Functional Brain Networks Across Diverse State of Bipolar Disorder With Relevance to Cognitive Deficits and Genetic and Transcriptomic Variations. | Ding Y et al. | — | 2025 | → |
| Single-molecule DNA analysis implicates brain mitochondria pathology in bipolar disorder. | Ohtani H et al. | — | 2025 | → |
| Single-nucleus chromatin accessibility profiling identifies cell types and functional variants contributing to major depression. | Chawla A et al. | — | 2025 | → |
| Sociodemographic, clinical, and genetic factors associated with self-reported antidepressant response outcomes in the UK Biobank. | Kamp M et al. | — | 2025 | → |
| Specification of claustro-amygdalar and palaeocortical neurons and circuits. | Kaur N et al. | — | 2025 | → |
| Spousal correlations for nine psychiatric disorders are consistent across cultures and persistent over generations. | Fan CC et al. | — | 2025 | → |
| Structure of a polymorphic repeat at the <i>CACNA1C</i> schizophrenia locus. | Moya R et al. | — | 2025 | → |
| Targeting the Roots of Psychosis: The Role of Aberrant Salience. | Marano G et al. | — | 2025 | → |
| The Association Among Bipolar Disorder, Mitochondrial Dysfunction, and Reactive Oxygen Species. | Kageyama Y et al. | — | 2025 | → |
| The Balance in the Head: How Developmental Factors Explain Relationships Between Brain Asymmetries and Mental Diseases. | Manns M et al. | — | 2025 | → |
| The breakthrough discoveries for thriving with bipolar disorder (BD<sup>2</sup>) integrated network longitudinal cohort protocol. | Baxi EG et al. | — | 2025 | → |
| The chloride intracellular channel 1 (CLIC1) is essential for microglial morphodynamics and neuroinflammation. | Rifat A et al. | — | 2025 | → |
| The left amygdala is genetically sexually-dimorphic: multi-omics analysis of structural MRI volumes. | Gui Y et al. | — | 2025 | → |
| The neuronal chromatin landscape in brains from individuals with schizophrenia is linked to early fetal development. | Girdhar K et al. | — | 2025 | → |
| The Swedish bipolar collection (SWEBIC). | Landén M et al. | — | 2025 | → |
| Three Distinct Pathways to First Episode Mania and Psychosis: Latent Class Analysis of Antecedent Psychopathology. | Ercis M et al. | — | 2025 | → |
| Transcriptional and epigenetic targets of MEF2C in human microglia contribute to cellular functions related to autism risk and age-related disease. | Nguyen C et al. | — | 2025 | → |
| Transdiagnostic findings across major depressive disorder, bipolar disorder and schizophrenia: A qualitative review. | Stein F et al. | — | 2025 | → |
| Underlying biological mechanisms of emotion dysregulation in bipolar disorder. | Durdurak BB et al. | — | 2025 | → |
| Unveiling genetic and biological links: exploring the intersection of autoimmune and psychiatric disorders. | Liwayiding A et al. | — | 2025 | → |
| Using multiomic integration to improve blood biomarkers of major depressive disorder: a case-control study. | Mokhtari A et al. | — | 2025 | → |
| Aberrant encoding of event saliency in the orbitofrontal cortex following loss of the psychiatric-associated circular RNA, circHomer1. | Zimmerman AJ et al. | — | 2024 | → |
| Advances in the understanding of the pathophysiology of schizophrenia and bipolar disorder through induced pluripotent stem cell models. | Perrottelli A et al. | — | 2024 | → |
| Alcohol drinking, DNA methylation and psychiatric disorders: A multi-omics Mendelian randomization study to investigate causal pathways. | Shi X et al. | — | 2024 | → |
| Altered Rhythmicity, Depressive Ruminative Thinking and Suicidal Ideation as Possible Correlates of an Unrecognized Autism Spectrum in Patients with Borderline Personality Disorder. | Cremone IM et al. | — | 2024 | → |
| A mammalian-specific Alex3/Gα<sub>q</sub> protein complex regulates mitochondrial trafficking, dendritic complexity, and neuronal survival. | Izquierdo-Villalba I et al. | — | 2024 | → |
| A multi-ancestry cerebral cortex transcriptome-wide association study identifies genes associated with smoking behaviors. | Tan Q et al. | — | 2024 | → |
| An evolutionary perspective on complex neuropsychiatric disease. | McClellan JM et al. | — | 2024 | → |
| A Plea for Nuance: Should People with a Family History of Bipolar Disorder Be Excluded from Clinical Trials of Psilocybin Therapy? | Downey AE et al. | — | 2024 | → |
| A Single-Nucleus Transcriptome-Wide Association Study Implicates Novel Genes in Depression Pathogenesis. | Zeng L et al. | — | 2024 | → |
| Assessing the validity of a self-reported clinical diagnosis of schizophrenia. | Woolway GE et al. | — | 2024 | → |
| Association of 11 variants of the dopaminergic and cognitive pathways genes with major depression, schizophrenia and bipolar disorder in the Pakistani population. | Nasir Hashmi A et al. | — | 2024 | → |
| Association of Chronic Obstructive Pulmonary Disease with Risk of Psychiatric Disorders: A Two-Sample Mendelian Randomization Study. | Zhang Q et al. | — | 2024 | → |
| Association of major depression, schizophrenia and bipolar disorder with thyroid cancer: a bidirectional two-sample mendelian randomized study. | Qiu R et al. | — | 2024 | → |
| Association of prescription data with clinical manifestations and polygenic risk scores in patients with bipolar I disorder: An exploratory study. | Park YM et al. | — | 2024 | → |
| Associations between benign paroxysmal positional vertigo and seven mental disorders: a two-sample Mendelian randomization study. | Liu S et al. | — | 2024 | → |
| Associations between Sjogren syndrome and psychiatric disorders in European populations: a 2-sample bidirectional Mendelian randomization study. | Pan L et al. | — | 2024 | → |
| Bipolar disorders and schizophrenia: discrete disorders? | Dines M et al. | — | 2024 | → |
| Bipolar disorder staging and the impact it has on its management: an update. | Dell'Osso B et al. | — | 2024 | → |
| Bipolar patients display stoichiometric imbalance of gene expression in post-mortem brain samples. | Holmgren A et al. | — | 2024 | → |
| Causal Association Between Sedentary Behaviors and Health Outcomes: A Systematic Review and Meta-Analysis of Mendelian Randomization Studies. | Gao Y et al. | — | 2024 | → |
| Causal effects between personality and psychiatric traits and lung cancer: a bidirectional two-sample Mendelian randomization and bibliometric study. | Chen S et al. | — | 2024 | → |
| Causal relationships between atopic dermatitis and psychiatric disorders: a bidirectional two-sample Mendelian randomization study. | Cao S et al. | — | 2024 | → |
| Central Channelopathies in Obesity. | Li AH et al. | — | 2024 | → |
| Changes in sleep patterns in people with a history of depression during the COVID-19 pandemic: a natural experiment. | Shin M et al. | — | 2024 | → |
| CircRNAs as a Novel Class of Potential Diagnostic Biomarkers in Bipolar Disorders. | Asemi R et al. | — | 2024 | → |
| Codes between Poles: Linking Transcriptomic Insights into the Neurobiology of Bipolar Disorder. | Garcia JPT et al. | — | 2024 | → |
| Common mental disorders and risk of female infertility: a two-sample Mendelian randomization study. | Mao D et al. | — | 2024 | → |
| Cortico-striatal differences in the epigenome in attention-deficit/ hyperactivity disorder. | Shastri GG et al. | — | 2024 | → |
| Discrimination between healthy participants and people with panic disorder based on polygenic scores for psychiatric disorders and for intermediate phenotypes using machine learning. | Ohi K et al. | — | 2024 | → |
| Emergence of Extracellular Vesicles as "Liquid Biopsy" for Neurological Disorders: Boom or Bust. | Kumar A et al. | — | 2024 | → |
| Emerging psychopathology and clinical staging in adolescent offspring of parents with bipolar disorder or schizophrenia-A longitudinal study. | Setiaman N et al. | — | 2024 | → |
| Epilepsy and psychiatric comorbidities: A bidirectional mendelian randomization study. | Chu H et al. | — | 2024 | → |
| Evidence for the additivity of rare and common variant burden throughout the spectrum of intellectual disability. | Urpa L et al. | — | 2024 | → |
| Exploring PDE5A upregulation in bipolar disorder: insights from single-nucleus RNA sequencing of human basal ganglia. | Bai Z et al. | — | 2024 | → |
| Exploring the intersection of polygenic risk scores and prenatal alcohol exposure: Unraveling the mental health equation. | Gerlikhman L et al. | — | 2024 | → |
| Factor analysis of lifetime psychopathology and its brain morphometric and genetic correlates in a transdiagnostic sample. | Krug A et al. | — | 2024 | → |
| Female genital prolapse and risk of psychiatric disorders: A two-sample Mendelian randomization analysis. | Zhou Q et al. | — | 2024 | → |
| Fibroblasts as an in vitro model of circadian genetic and genomic studies. | Francia M et al. | — | 2024 | → |
| Focal adhesion is associated with lithium response in bipolar disorder: evidence from a network-based multi-omics analysis. | Niemsiri V et al. | — | 2024 | → |
| Frailty and psychiatric disorders: A bidirectional Mendelian randomization study. | Chen JH et al. | — | 2024 | → |
| Functional classes of SNPs related to psychiatric disorders and behavioral traits contrast with those related to neurological disorders. | Reimers MA et al. | — | 2024 | → |
| Gain of bipolar disorder-related lncRNA AP1AR-DT in mice induces depressive and anxiety-like behaviors by reducing Negr1-mediated excitatory synaptic transmission. | Li S et al. | — | 2024 | → |
| Gene-environment interactions in the influence of maternal education on adolescent neurodevelopment using ABCD study. | Shi R et al. | — | 2024 | → |
| Gene-gene interaction analysis for age at onset of bipolar disorder in a Korean population. | Park M et al. | — | 2024 | → |
| Genetically predicted fatty liver disease and risk of psychiatric disorders: A mendelian randomization study. | Xu WM et al. | — | 2024 | → |
| Genetically predicted major depression causally increases the risk of temporomandibular joint disorders. | Wu S et al. | — | 2024 | → |
| Genetic architectures of cerebral ventricles and their overlap with neuropsychiatric traits. | Ge YJ et al. | — | 2024 | → |
| Genetic associations and potential mediators between psychiatric disorders and irritable bowel syndrome: a Mendelian randomization study with mediation analysis. | Zhang T et al. | — | 2024 | → |
| Genetic-epigenetic-neuropeptide associations in mood and anxiety disorders: Toward personalized medicine. | Gilani M et al. | — | 2024 | → |
| Genetic evidence for causal effects of immune dysfunction in psychiatric disorders: where are we? | Iakunchykova O et al. | — | 2024 | → |
| Genetic evidence for the causal relations between metabolic syndrome and psychiatric disorders: a Mendelian randomization study. | Gao X et al. | — | 2024 | → |
| Genetic risk for hospitalization of African American patients with severe mental illness reveals HLA loci. | Lori A et al. | — | 2024 | → |
| Genetics of cell-type-specific post-transcriptional gene regulation during human neurogenesis. | Aygün N et al. | — | 2024 | → |
| Genome-wide association study of early-onset and late-onset postpartum depression: the IGEDEPP prospective study. | Tebeka S et al. | — | 2024 | → |
| Genome-wide DNA methylation risk scores for schizophrenia derived from blood and brain tissues further explain the genetic risk in patients stratified by polygenic risk scores for schizophrenia and bipolar disorder. | Ohi K et al. | — | 2024 | → |
| Genomic structural equation modeling reveals latent phenotypes in the human cortex with distinct genetic architecture. | Morey RA et al. | — | 2024 | → |
| Identifying novel proteins underlying bipolar disorder via integrating pQTLs of the plasma, CSF, and brain with GWAS summary data. | Xiao Z et al. | — | 2024 | → |
| Immunogenetics of lithium response and psychiatric phenotypes in patients with bipolar disorder. | Herrera-Rivero M et al. | — | 2024 | → |
| Impaired neural stress resistance and loss of REST in bipolar disorder. | Meyer K et al. | — | 2024 | → |
| Infants' looking preferences for social versus non-social objects reflect genetic variation. | Portugal AM et al. | — | 2024 | → |
| Investigation of Genetic Changes in Three Families with Bipolar Disease. | Çolak-Geniş E et al. | — | 2024 | → |
| Ketogenic Diet as a Nutritional Metabolic Intervention for Obsessive-Compulsive Disorder: A Narrative Review. | Lounici A et al. | — | 2024 | → |
| Leveraging single-cell ATAC-seq and RNA-seq to identify disease-critical fetal and adult brain cell types. | Kim SS et al. | — | 2024 | → |
| Lifestyle Factors Counteract the Neurodevelopmental Impact of Genetic Risk for Accelerated Brain Aging in Adolescence. | Petrican R et al. | — | 2024 | → |
| Meta-analysis of set-based multiple phenotype association test based on GWAS summary statistics from different cohorts. | Zhu L et al. | — | 2024 | → |
| Mismatch negativity and polygenic risk scores for schizophrenia and bipolar disorder. | Pentz AB et al. | — | 2024 | → |
| Mitochondrial dysfunction in psychiatric disorders. | Ni P et al. | — | 2024 | → |
| Multimodal Neuroimaging Summary Scores as Neurobiological Markers of Psychosis. | Rodrigue AL et al. | — | 2024 | → |
| Multiomic profiling of transcription factor binding and function in human brain. | Loupe JM et al. | — | 2024 | → |
| NEK4 modulates circadian fluctuations of emotional behaviors and synaptogenesis in male mice. | Yang ZH et al. | — | 2024 | → |
| Network-wide risk convergence in gene co-expression identifies reproducible genetic hubs of schizophrenia risk. | Borcuk C et al. | — | 2024 | → |
| Oxidation of DNA and RNA in young patients with newly diagnosed bipolar disorder and relatives. | Coello K et al. | — | 2024 | → |
| Pathophysiological relationships between cognitive deficit in bipolar affective disorder and metabolic syndrome. | PiedrahÃta Palacio N et al. | — | 2024 | → |
| Patterns of stressful life events and polygenic scores for five mental disorders and neuroticism among adults with depression. | Crouse JJ et al. | — | 2024 | → |
| Pharmacogenomic overlap between antidepressant treatment response in major depression & antidepressant associated treatment emergent mania in bipolar disorder. | Nuñez NA et al. | — | 2024 | → |
| Pharmacogenomics and response to lithium in bipolar disorder. | Paribello P et al. | — | 2024 | → |
| Polygenic risk for major depression, attention deficit hyperactivity disorder, neuroticism, and schizophrenia are correlated with experience of intimate partner violence. | Ratanatharathorn A et al. | — | 2024 | → |
| Polygenic risk for schizophrenia and bipolar disorder in relation to cardiovascular biomarkers. | Reponen EJ et al. | — | 2024 | → |
| Polygenic risk of social isolation behavior and its influence on psychopathology and personality. | Socrates AJ et al. | — | 2024 | → |
| Processing speed mediates the relationship between DDR1 and psychosocial functioning in euthymic patients with bipolar disorder presenting psychotic symptoms. | Aranda S et al. | — | 2024 | → |
| Progress and Implications from Genetic Studies of Bipolar Disorder. | Kong L et al. | — | 2024 | → |
| Progress and trends of research on mineral elements for depression. | Gao B et al. | — | 2024 | → |
| Psychiatric Polygenic Risk Scores Across Youth With Bipolar Disorder, Youth at High Risk for Bipolar Disorder, and Controls. | Jiang X et al. | — | 2024 | → |
| Psychiatric polygenic risk scores: Experience, hope for utility, and concerns among child and adolescent psychiatrists. | Merner AR et al. | — | 2024 | → |
| Replication of previous autism-GWAS hits suggests the association between <i>NAA1, SORCS3,</i> and <i>GSDME</i> and autism in the Han Chinese population. | Lin F et al. | — | 2024 | → |
| Scaled and efficient derivation of loss-of-function alleles in risk genes for neurodevelopmental and psychiatric disorders in human iPSCs. | Zhang H et al. | — | 2024 | → |
| Schizophrenia polygenic risk scores, clinical variables and genetic pathways as predictors of phenotypic traits of bipolar I disorder. | Grigoroiu-Serbanescu M et al. | — | 2024 | → |
| Sex affects transcriptional associations with schizophrenia across the dorsolateral prefrontal cortex, hippocampus, and caudate nucleus. | Benjamin KJM et al. | — | 2024 | → |
| Sex-Specific Association Between Genetic Risk of Psychiatric Disorders and Cardiovascular Diseases. | Jiang JC et al. | — | 2024 | → |
| Single-cell multi-cohort dissection of the schizophrenia transcriptome. | Ruzicka WB et al. | — | 2024 | → |
| SnapHiC-G: identifying long-range enhancer-promoter interactions from single-cell Hi-C data via a global background model. | Liu W et al. | — | 2024 | → |
| Socioeconomic status, personality, and major mental disorders: a bidirectional Mendelian randomization study. | Xu Q et al. | — | 2024 | → |
| Spatial, transcriptomic, and epigenomic analyses link dorsal horn neurons to chronic pain genetic predisposition. | Arokiaraj CM et al. | — | 2024 | → |
| Subset-based method for cross-tissue transcriptome-wide association studies improves power and interpretability. | Guo X et al. | — | 2024 | → |
| The Association of Hippocampal Long-Term Potentiation-Induced Gene Expression with Genetic Risk for Psychosis. | Wellard NL et al. | — | 2024 | → |
| The causal relationship between severe mental illness and risk of lung carcinoma. | Chen X et al. | — | 2024 | → |
| The causal relationship of female infertility and psychiatric disorders in the European population: a bidirectional two-sample Mendelian randomization study. | Zeng P et al. | — | 2024 | → |
| The effect of polygenic risk score and childhood adversity on transdiagnostic symptom dimensions at first-episode psychosis: evidence for an affective pathway to psychosis. | Alameda L et al. | — | 2024 | → |
| The effects of psychiatric disorders on the risk of chronic heart failure: a univariable and multivariable Mendelian randomization study. | Chen Y et al. | — | 2024 | → |
| The Genetic Architecture of Amygdala Nuclei. | Mufford MS et al. | — | 2024 | → |
| The genetic architecture of substance use and its diverse correlations with mental health traits. | Wormington B et al. | — | 2024 | → |
| The genetic architecture of the human hypothalamus and its involvement in neuropsychiatric behaviours and disorders. | Chen SD et al. | — | 2024 | → |
| The genetic association between bipolar disorder and dementia: a qualitative review. | Hirakawa H et al. | — | 2024 | → |
| The impact of assortative mating, participation bias and socioeconomic status on the polygenic risk of behavioural and psychiatric traits. | Cabrera-Mendoza B et al. | — | 2024 | → |
| The interaction effects of age, APOE and common environmental risk factors on human brain structure. | Chen J et al. | — | 2024 | → |
| The link between alterations in circadian rhythms and lipid metabolism in bipolar disorder: the hypothesis of lipid droplets. | Pereira AC et al. | — | 2024 | → |
| The relationship between emotional disorders and heart rate variability: A Mendelian randomization study. | Luo X et al. | — | 2024 | → |
| The shared genetic etiology of antisocial behavior and psychiatric disorders: Insights from pleiotropy and causality analysis. | Wang S et al. | — | 2024 | → |
| The structure of psychiatric comorbidity without selection and assortative mating. | Ayorech Z et al. | — | 2024 | → |
| Transcriptomics : Approaches to Quantifying Gene Expression and Their Application to Studying the Human Brain. | Liharska L et al. | — | 2024 | → |
| Unique genetic and risk-factor profiles in clusters of major depressive disorder-related multimorbidity trajectories. | Gezsi A et al. | — | 2024 | → |
| Whole-exome sequencing identifies protein-coding variants associated with brain iron in 29,828 individuals. | Gong W et al. | — | 2024 | → |
| Whole-exome sequencing in UK Biobank reveals rare genetic architecture for depression. | Tian R et al. | — | 2024 | → |
| 150 risk variants for diverticular disease of intestine prioritize cell types and enable polygenic prediction of disease susceptibility. | Wu Y et al. | — | 2023 | → |
| Aberrant functional connectivity within and between brain networks in patients with early-onset bipolar disorder. | Hu Z et al. | — | 2023 | → |
| Advances in the pathophysiology of bipolar disorder. | Wartchow KM et al. | — | 2023 | → |
| A genetically informed Registered Report on adverse childhood experiences and mental health. | Baldwin JR et al. | — | 2023 | → |
| Alternative polyadenylation transcriptome-wide association study identifies APA-linked susceptibility genes in brain disorders. | Cui Y et al. | — | 2023 | → |
| Alternative splicing in mouse brains affected by psychological stress is enriched in the signaling, neural transmission and blood-brain barrier pathways. | Wang F et al. | — | 2023 | → |
| Annotating genetic variants to target genes using H-MAGMA. | Sey NYA et al. | — | 2023 | → |
| A pilot investigation of differential hydroxymethylation levels in patient-derived neural stem cells implicates altered cortical development in bipolar disorder. | Kumar A et al. | — | 2023 | → |
| A pilot pharmacogenetic study of calcium channel blocker treatment of bipolar mania. | Li M et al. | — | 2023 | → |
| A preliminary composite of blood-based biomarkers to distinguish major depressive disorder and bipolar disorder in adolescents and adults. | Huang J et al. | — | 2023 | → |
| A resource of induced pluripotent stem cell (iPSC) lines including clinical, genomic, and cellular data from genetically isolated families with mood and psychotic disorders. | Detera-Wadleigh SD et al. | — | 2023 | → |
| Assessing the causal association of trauma with subsequent psychiatric disorders by a Mendelian randomization study trauma and common psychiatric disorders. | Gu D et al. | — | 2023 | → |
| Associated Genetics and Connectomic Circuitry in Schizophrenia and Bipolar Disorder. | Wei Y et al. | — | 2023 | → |
| Association between 14 candidate genes, PM2.5, and affective disorders: a study of the Taiwan Biobank. | Ma KJ et al. | — | 2023 | → |
| Association between brain similarity to severe mental illnesses and comorbid cerebral, physical, and cognitive impairments. | Ma Y et al. | — | 2023 | → |
| BrainGENIE: The Brain Gene Expression and Network Imputation Engine. | Hess JL et al. | — | 2023 | → |
| Brain-gut microbiota multimodal predictive model in patients with bipolar depression. | Xi C et al. | — | 2023 | → |
| Brain insulin signaling as a potential mediator of early life adversity effects on physical and mental health. | Alberry B et al. | — | 2023 | → |
| Brain Lipids and Lipid Droplet Dysregulation in Alzheimer's Disease and Neuropsychiatric Disorders. | Zhao X et al. | — | 2023 | → |
| Calcium Homeostasis and Psychiatric Disorders: A Mendelian Randomization Study. | Jiang M et al. | — | 2023 | → |
| Causal relationship between psychiatric traits and temporomandibular disorders: a bidirectional two-sample Mendelian randomization study. | Xiang Y et al. | — | 2023 | → |
| Cellular Diversity in Human Subgenual Anterior Cingulate and Dorsolateral Prefrontal Cortex by Single-Nucleus RNA-Sequencing. | Kim B et al. | — | 2023 | → |
| Circulating S100B levels at birth and risk of six major neuropsychiatric or neurological disorders: a two-sample Mendelian Randomization Study. | Pan M et al. | — | 2023 | → |
| Clinical characteristics indexing genetic differences in bipolar disorder - a systematic review. | van Loo HM et al. | — | 2023 | → |
| Clinical utility of polygenic risk scores: a critical 2023 appraisal. | Koch S et al. | — | 2023 | → |
| Co-Aggregation and Parallel Aggregation of Specific Proteins in Major Mental Illness. | Samardžija B et al. | — | 2023 | → |
| Co-development of attention deficit hyperactivity disorder and autistic trait trajectories from childhood to early adulthood. | Shakeshaft A et al. | — | 2023 | → |
| Cognitive performances across individuals at high genetic risk for schizophrenia, high genetic risk for bipolar disorder, and low genetic risks: a combined polygenic risk score approach. | Ohi K et al. | — | 2023 | → |
| Combinations of genes at the 16p11.2 and 22q11.2 CNVs contribute to neurobehavioral traits. | Vysotskiy M et al. | — | 2023 | → |
| Computational Modeling of the n-Back Task in the ABCD Study: Associations of Drift Diffusion Model Parameters to Polygenic Scores of Mental Disorders and Cardiometabolic Diseases. | Pedersen ML et al. | — | 2023 | → |
| Consensus molecular environment of schizophrenia risk genes in coexpression networks shifting across age and brain regions. | Pergola G et al. | — | 2023 | → |
| Contributions of circadian clock genes to cell survival in fibroblast models of lithium-responsive bipolar disorder. | Mishra HK et al. | — | 2023 | → |
| CRISPRi screening reveals regulators of tau pathology shared between exosomal and vesicle-free tau. | Polanco JC et al. | — | 2023 | → |
| Cross-disorder GWAS meta-analysis of endocannabinoid DNA variations in major depressive disorder, bipolar disorder, attention deficit hyperactivity disorder, autism spectrum disorder, and schizophrenia. | Kim HK et al. | — | 2023 | → |
| Deep exome sequencing identifies enrichment of deleterious mosaic variants in neurodevelopmental disorder genes and mitochondrial tRNA regions in bipolar disorder. | Nishioka M et al. | — | 2023 | → |
| Deep proteomics identifies shared molecular pathway alterations in synapses of patients with schizophrenia and bipolar disorder and mouse model. | Aryal S et al. | — | 2023 | → |
| Depressive symptoms and neuroticism-related traits are the main factors associated with wellbeing independent of the history of lifetime depression in the UK Biobank. | Fabbri C et al. | — | 2023 | → |
| Differential characteristics of bipolar I and II disorders: a retrospective, cross-sectional evaluation of clinical features, illness course, and response to treatment. | Brancati GE et al. | — | 2023 | → |
| Discovery and replication of blood-based proteomic signature of PTSD in 9/11 responders. | Waszczuk MA et al. | — | 2023 | → |
| Distributed genetic effects of the corpus callosum subregions suggest links to neuropsychiatric disorders and related traits. | Campbell ML et al. | — | 2023 | → |
| Does circadian dysrhythmia drive the switch into high- or low-activation states in bipolar I disorder? | Hickie IB et al. | — | 2023 | → |
| Effects of Exercise on Functional Recovery in Patients with Bipolar Depression: A Study Protocol for a Randomized Controlled Trial. | Hamada F et al. | — | 2023 | → |
| Effects of major depression and bipolar disorder on erectile dysfunction: a two-sample mendelian randomization study. | Chen WK et al. | — | 2023 | → |
| Emerging trends in gene and bipolar disorder research: a bibliometric analysis and network visualisation. | Zakaria WNA et al. | — | 2023 | → |
| Evidence for a causal association between psoriasis and psychiatric disorders using a bidirectional Mendelian randomization analysis in up to 902,341 individuals. | Wang Y et al. | — | 2023 | → |
| Exploratory factor analysis of shared and specific genetic associations in depression and anxiety. | Li C et al. | — | 2023 | → |
| Exploring the Genetic Link Between Thyroid Dysfunction and Common Psychiatric Disorders: A Specific Hormonal or a General Autoimmune Comorbidity. | Soheili-Nezhad S et al. | — | 2023 | → |
| Exploring the Hypothesis of a Schizophrenia and Bipolar Disorder Continuum: Biological, Genetic and Pharmacologic Data. | de Sousa TR et al. | — | 2023 | → |
| Expression of ANK3 moderates the association between childhood trauma and affective traits in severe mental disorders. | Aas M et al. | — | 2023 | → |
| Family environment and polygenic risk in the bipolar high-risk context. | Stapp EK et al. | — | 2023 | → |
| First-Episode Psychosis Patients Who Deteriorated in the Premorbid Period Do Not Have Higher Polygenic Risk Scores Than Others: A Cluster Analysis of EU-GEI Data. | Ferraro L et al. | — | 2023 | → |
| Functional Alterations in Patients with Bipolar Disorder and Their Unaffected First-Degree Relatives: Insight from Genetic, Epidemiological, and Neuroimaging Data. | Zhang H et al. | — | 2023 | → |
| General <i>v</i>. specific vulnerabilities: polygenic risk scores and higher-order psychopathology dimensions in the Adolescent Brain Cognitive Development (ABCD) Study. | Waszczuk MA et al. | — | 2023 | → |
| Genetic and Geographical Associations With Six Dimensions of Psychotic Experiences in Adolesence. | Maxwell J et al. | — | 2023 | → |
| Genetic and Structural Brain Correlates of Cognitive Subtypes Across Youth at Family Risk for Schizophrenia and Bipolar Disorder. | Valli I et al. | — | 2023 | → |
| Genetic architecture of the white matter connectome of the human brain. | Sha Z et al. | — | 2023 | → |
| Genetic examination of the Mood Disorder Questionnaire and its relationship with bipolar disorder. | Mundy J et al. | — | 2023 | → |
| Genetic, individual, and familial risk correlates of brain network controllability in major depressive disorder. | Hahn T et al. | — | 2023 | → |
| Genetic liability to bipolar disorder and body mass index: A bidirectional two-sample Mendelian randomization study. | Byg LM et al. | — | 2023 | → |
| Genetic modifiers of synucleinopathies-lessons from experimental models. | Lee RMQ et al. | — | 2023 | → |
| Genetic nurture versus genetic transmission of risk for ADHD traits in the Norwegian Mother, Father and Child Cohort Study. | Pingault JB et al. | — | 2023 | → |
| Genetic patterning for child psychopathology is distinct from that for adults and implicates fetal cerebellar development. | Hughes DE et al. | — | 2023 | → |
| Genetics of bipolar disorder: insights into its complex architecture and biology from common and rare variants. | Hara T et al. | — | 2023 | → |
| Genetic substrates of bipolar disorder risk in Latino families. | Escamilla M et al. | — | 2023 | → |
| Genetic variations in the retrograde endocannabinoid signaling pathway in Chinese patients with major depressive disorder. | Xu H et al. | — | 2023 | → |
| Genome-wide association study identifies four pan-ancestry loci for suicidal ideation in the Million Veteran Program. | Ashley-Koch AE et al. | — | 2023 | → |
| Genome-wide association study of brain biochemical phenotypes reveals distinct genetic architecture of Alzheimer's disease related proteins. | Oatman SR et al. | — | 2023 | → |
| Genome-wide association study of cerebellar white matter microstructure and genetic overlap with common brain disorders. | Wu BS et al. | — | 2023 | → |
| Genome-wide significant risk loci for mood disorders in the Old Order Amish founder population. | Humphries EM et al. | — | 2023 | → |
| Genomic Investigation of Remission and Relapse of Psychotic Depression Treated with Sertraline plus Olanzapine: The STOP-PD II Study. | Men X et al. | — | 2023 | → |
| Genomic regulatory sequences in the pathogenesis of bipolar disorder. | Levchenko A et al. | — | 2023 | → |
| GWAS-identified bipolar disorder risk allele in the FADS1/2 gene region links mood episodes and unsaturated fatty acid metabolism in mutant mice. | Yamamoto H et al. | — | 2023 | → |
| GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors. | Docherty AR et al. | — | 2023 | → |
| Heterozygosity for neuronal ceroid lipofuscinosis predisposes to bipolar disorder. | Privitera F et al. | — | 2023 | → |
| Identification of four novel loci associated with psychotropic drug-induced weight gain in a Swiss psychiatric longitudinal study: A GWAS analysis. | Sjaarda J et al. | — | 2023 | → |
| Identification of Novel, Replicable Genetic Risk Loci for Suicidal Thoughts and Behaviors Among US Military Veterans. | Kimbrel NA et al. | — | 2023 | → |
| Immunoglobulin genes expressed in lymphoblastoid cell lines discern and predict lithium response in bipolar disorder patients. | Mizrahi L et al. | — | 2023 | → |
| Impact of Copy Number Variants and Polygenic Risk Scores on Psychopathology in the UK Biobank. | Mollon J et al. | — | 2023 | → |
| Increase in power by obtaining 10 or more controls per case when type-1 error is small in large-scale association studies. | Katki HA et al. | — | 2023 | → |
| Induction of dopaminergic neurons for neuronal subtype-specific modeling of psychiatric disease risk. | Powell SK et al. | — | 2023 | → |
| Inferring cell-type-specific causal gene regulatory networks during human neurogenesis. | Aygün N et al. | — | 2023 | → |
| Insomnia and circadian rhythm: a bibliometrics study and visualization analysis <i>via</i> CiteSpace. | He QY et al. | — | 2023 | → |
| Investigating Direct and Indirect Genetic Effects in Attention-Deficit/Hyperactivity Disorder Using Parent-Offspring Trios. | Martin J et al. | — | 2023 | → |
| Investigation of convergent and divergent genetic influences underlying schizophrenia and alcohol use disorder. | Johnson EC et al. | — | 2023 | → |
| Is adjustment disorder genetically correlated with depression, anxiety, or risk-tolerant personality trait? | Ohi K et al. | — | 2023 | → |
| Kynurenine pathway abnormalities are state-specific but not diagnosis-specific in schizophrenia and bipolar disorder. | Skorobogatov K et al. | — | 2023 | → |
| Leukocyte telomere length and bipolar disorder risk: evidence from Mendelian randomization analysis. | Lu L et al. | — | 2023 | → |
| Leveraging genetic overlap between irritability and psychiatric disorders to identify genetic variants of major psychiatric disorders. | Jung K et al. | — | 2023 | → |
| Lineage specific 3D genome structure in the adult human brain and neurodevelopmental changes in the chromatin interactome. | Rahman S et al. | — | 2023 | → |
| Lithium rescues dendritic abnormalities in Ank3 deficiency models through the synergic effects of GSK3β and cyclic AMP signaling pathways. | Piguel NH et al. | — | 2023 | → |
| Long-term exposure to ambient air pollution, genetic susceptibility, and the incidence of bipolar disorder: A prospective cohort study. | Li D et al. | — | 2023 | → |
| Mapping anorexia nervosa genes to clinical phenotypes. | Johnson JS et al. | — | 2023 | → |
| Mapping Normative Trajectories of Cognitive Function and Its Relation to Psychopathology Symptoms and Genetic Risk in Youth. | Kjelkenes R et al. | — | 2023 | → |
| Mapping the cortico-striatal transcriptome in attention deficit hyperactivity disorder. | Sudre G et al. | — | 2023 | → |
| Mapping the scientific research on bipolar disorder: A scientometric study of hotspots, bursts, and trends. | Zhu W et al. | — | 2023 | → |
| Maternal depression and the polygenic p factor: A family perspective on direct and indirect effects. | Ayorech Z et al. | — | 2023 | → |
| Mendelian randomization investigation highlights different roles of selenium status in mental disorders. | Guo X et al. | — | 2023 | → |
| Mendelian randomization shows depression increases the risk of type 2 diabetes. | Jin H et al. | — | 2023 | → |
| Methylation in MAD1L1 is associated with the severity of suicide attempt and phenotypes of depression. | Sokolov AV et al. | — | 2023 | → |
| Microbiota-gut-brain axis mechanisms in the complex network of bipolar disorders: potential clinical implications and translational opportunities. | Ortega MA et al. | — | 2023 | → |
| Molecular programs of regional specification and neural stem cell fate progression in macaque telencephalon. | Micali N et al. | — | 2023 | → |
| Multimodal mapping of regional brain vulnerability to focal cortical dysplasia. | Lee HM et al. | — | 2023 | → |
| Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neurons. | Zhang S et al. | — | 2023 | → |
| Multivariate analyses of molecular genetic associations between childhood psychopathology and adult mood disorders and related traits. | Akingbuwa WA et al. | — | 2023 | → |
| Neural progenitor cells derived from lithium responsive and non-responsive bipolar disorder patients exhibit distinct sensitivity to cell death following methamphetamine. | Mishra HK et al. | — | 2023 | → |
| Neurite outgrowth deficits caused by rare PLXNB1 mutation in pediatric bipolar disorder. | Yang G et al. | — | 2023 | → |
| New and emerging approaches to treat psychiatric disorders. | Scangos KW et al. | — | 2023 | → |
| New insights from the last decade of research in psychiatric genetics: discoveries, challenges and clinical implications. | Andreassen OA et al. | — | 2023 | → |
| Ocular and neural genes jointly regulate the visuospatial working memory in ADHD children. | Zhao Y et al. | — | 2023 | → |
| Opportunities and limitations for studying neuropsychiatric disorders using patient-derived induced pluripotent stem cells. | Hong Y et al. | — | 2023 | → |
| Overlap of Neuroanatomical Involvement in Frontotemporal Dementia and Primary Psychiatric Disorders: A Meta-analysis. | Ulugut H et al. | — | 2023 | → |
| Pathophysiological Roles of Auxiliary Calcium Channel α<sub>2</sub>δ Subunits. | Hessenberger M et al. | — | 2023 | → |
| Phenotypic and genetic factors associated with donation of DNA and consent to record linkage for prescription history in the Australian Genetics of Depression Study. | Gomez L et al. | — | 2023 | → |
| Phosphodiesterase and psychiatric disorders: a two-sample Mendelian randomization study. | Jiang M et al. | — | 2023 | → |
| Polygenic contributions to performance on the Balloon Analogue Risk Task. | Nurmi EL et al. | — | 2023 | → |
| Polygenic risk of major depressive disorder as a risk factor for venous thromboembolism. | Ward J et al. | — | 2023 | → |
| Polygenic risk scores of lithium response and treatment resistance in major depressive disorder. | Xiong Y et al. | — | 2023 | → |
| Polygenic scores for psychiatric disorders in a diverse postmortem brain tissue cohort. | Duncan L et al. | — | 2023 | → |
| Preliminary Evidence for Genetic Nurture in Depression and Neuroticism Through Polygenic Scores. | Tubbs JD et al. | — | 2023 | → |
| Prioritizing genes associated with brain disorders by leveraging enhancer-promoter interactions in diverse neural cells and tissues. | Zhao X et al. | — | 2023 | → |
| Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders. | Pintacuda G et al. | — | 2023 | → |
| RNA Biomarkers in Bipolar Disorder and Response to Mood Stabilizers. | Pisanu C et al. | — | 2023 | → |
| Schizophrenia-associated NRXN1 deletions induce developmental-timing- and cell-type-specific vulnerabilities in human brain organoids. | Sebastian R et al. | — | 2023 | → |
| Severe mental illness and the risk of breast cancer: A two-sample, two-step multivariable Mendelian randomization study. | Cui Y et al. | — | 2023 | → |
| Shared genetics of psychiatric disorders and type 2 diabetes:a large-scale genome-wide cross-trait analysis. | Ding H et al. | — | 2023 | → |
| Subcortical volumetric alterations in four major psychiatric disorders: a mega-analysis study of 5604 subjects and a volumetric data-driven approach for classification. | Okada N et al. | — | 2023 | → |
| Swedish multimodal cohort of patients with anxiety or depression treated with internet-delivered psychotherapy (MULTI-PSYCH). | Boberg J et al. | — | 2023 | → |
| Symptom dimensions of major depression in a large community-based cohort. | Wainberg M et al. | — | 2023 | → |
| The association between polygenic risk scores for mental disorders and social cognition: A scoping review. | Fusar-Poli L et al. | — | 2023 | → |
| The Big (Genetic) Sort? A Research Note on Migration Patterns and Their Genetic Imprint in the United Kingdom. | Furuya S et al. | — | 2023 | → |
| The causal relationship between circulating biomarkersand the risk of bipolar disorder: A two-sample Mendelian randomization study. | Hu JJ et al. | — | 2023 | → |
| The genetic architecture of fornix white matter microstructure and their involvement in neuropsychiatric disorders. | Ou YN et al. | — | 2023 | → |
| The genetic architecture of human amygdala volumes and their overlap with common brain disorders. | Ou YN et al. | — | 2023 | → |
| The Genetic Side of the Mood: A Scientometric Review of the Genetic Basis of Mood Disorders. | Bonacina G et al. | — | 2023 | → |
| The higher the household income, the lower the possibility of depression and anxiety disorder: evidence from a bidirectional Mendelian randomization study. | Liu G et al. | — | 2023 | → |
| The impact of rare protein coding genetic variation on adult cognitive function. | Chen CY et al. | — | 2023 | → |
| The Role of the Gut Microbiome in Bipolar Disorder and its Common Medical Comorbidities. | Jones GH et al. | — | 2023 | → |
| The shared genetic architecture of smoking behaviours and psychiatric disorders: evidence from a population-based longitudinal study in England. | Ajnakina O et al. | — | 2023 | → |
| The shared genetic landscape of blood cell traits and risk of neurological and psychiatric disorders. | Yang Y et al. | — | 2023 | → |
| Towards the First Biomarker Test for Bipolar Spectrum Disorder: An Evaluation of 199 Patients in an Outpatient Setting. | Zamar A et al. | — | 2023 | → |
| Transcriptional and functional effects of lithium in bipolar disorder iPSC-derived cortical spheroids. | Osete JR et al. | — | 2023 | → |
| Transferability of the PRS estimates for height and BMI obtained from the European ethnic groups to the Western Russian populations. | Albert EA et al. | — | 2023 | → |
| Understanding the relationship between loneliness, substance use traits and psychiatric disorders: A genetically informed approach. | Martin E et al. | — | 2023 | → |
| Unraveling shared susceptibility loci and Mendelian genetic associations linking educational attainment with multiple neuropsychiatric disorders. | Chen D et al. | — | 2023 | → |
| Use of multiple polygenic risk scores for distinguishing schizophrenia-spectrum disorder and affective psychosis categories in a first-episode sample; the EU-GEI study. | Rodriguez V et al. | — | 2023 | → |
| Using allele scores to identify confounding by reverse causation: studies of alcohol consumption as an exemplar. | Sallis HM et al. | — | 2023 | → |
| Youth Team Sports Participation Associates With Reduced Dimensional Psychopathology Through Interaction With Biological Risk Factors. | Kunitoki K et al. | — | 2023 | → |
| Accounting for age of onset and family history improves power in genome-wide association studies. | Pedersen EM et al. | — | 2022 | → |
| A data harmonization pipeline to leverage external controls and boost power in GWAS. | Chen D et al. | — | 2022 | → |
| A genome-wide association study of suicide attempts in the million veterans program identifies evidence of pan-ancestry and ancestry-specific risk loci. | Kimbrel NA et al. | — | 2022 | → |
| Allopurinol, dipyridamole and calcium channel blockers in the treatment of bipolar disorder - A nationwide cohort study. | Lintunen J et al. | — | 2022 | → |
| Altered dynamic amplitude of low-frequency fluctuation between bipolar type I and type II in the depressive state. | Liu W et al. | — | 2022 | → |
| Amygdala and anterior cingulate transcriptomes from individuals with bipolar disorder reveal downregulated neuroimmune and synaptic pathways. | Zandi PP et al. | — | 2022 | → |
| An atlas of genetic correlations between gestational age and common psychiatric disorders. | Yao Y et al. | — | 2022 | → |
| An atlas of transcriptionally defined cell populations in the rat ventral tegmental area. | Phillips RA et al. | — | 2022 | → |
| A Novel Framework for Analysis of the Shared Genetic Background of Correlated Traits. | Svishcheva GR et al. | — | 2022 | → |
| Applications of Mendelian randomization in psychiatry: a comprehensive systematic review. | Saccaro LF et al. | — | 2022 | → |
| Assessment of the relationships between genetic determinants of thyroid functions and bipolar disorder: A mendelian randomization study. | Chen G et al. | — | 2022 | → |
| Association between CACNA1C gene rs100737 polymorphism and glutamatergic neurometabolites in bipolar disorder. | Scotti-Muzzi E et al. | — | 2022 | → |
| Association Between Polygenic Risk Scores and Outcome of ECT. | Sigström R et al. | — | 2022 | → |
| Association of Etiological Factors for Hypomanic Symptoms, Bipolar Disorder, and Other Severe Mental Illnesses. | Hosang GM et al. | — | 2022 | → |
| Association of maternal polygenic risk scores for mental illness with perinatal risk factors for offspring mental illness. | Ratanatharathorn A et al. | — | 2022 | → |
| Association of polygenic risk for schizophrenia with fast sleep spindle density depends on pro-cognitive variants. | Schilling C et al. | — | 2022 | → |
| Association of polygenic risk scores and hair cortisol with mental health trajectories during COVID lockdown. | Ahrens KF et al. | — | 2022 | → |
| Associations and limited shared genetic aetiology between bipolar disorder and cardiometabolic traits in the UK Biobank. | Fürtjes AE et al. | — | 2022 | → |
| Associations between brain imaging and polygenic scores of mental health and educational attainment in children aged 9-11. | Fernandez-Cabello S et al. | — | 2022 | → |
| A Systematic Review of Genetic Polymorphisms Associated with Bipolar Disorder Comorbid to Substance Abuse. | de Marco A et al. | — | 2022 | → |
| Blood and brain gene expression signatures of chronic intermittent ethanol consumption in mice. | Ferguson LB et al. | — | 2022 | → |
| Causal relationship between bipolar disorder and inflammatory bowel disease: A bidirectional two-sample mendelian randomization study. | Wang Z et al. | — | 2022 | → |
| Characterizing mood disorders in the AFFECT study: a large, longitudinal, and phenotypically rich genetic cohort in the US. | Dalby M et al. | — | 2022 | → |
| Characterizing the polygenic overlaps of bipolar disorder subtypes with schizophrenia and major depressive disorder. | Li Z et al. | — | 2022 | → |
| Chronbiologically-based sub-groups in bipolar I disorder: A latent profile analysis. | Gonzalez R et al. | — | 2022 | → |
| Circulating miRNAs as Potential Biomarkers for Patient Stratification in Bipolar Disorder: A Combined Review and Data Mining Approach. | Clausen AR et al. | — | 2022 | → |
| Cohort profile: the Swedish National Quality Register for bipolar disorder(BipoläR). | Pålsson E et al. | — | 2022 | → |
| Collective genomic segments with differential pleiotropic patterns between cognitive dimensions and psychopathology. | Lam M et al. | — | 2022 | → |
| Comprehensive exploration of the genetic contribution of the dopaminergic and serotonergic pathways to psychiatric disorders. | Cabana-DomÃnguez J et al. | — | 2022 | → |
| Convergence of case-specific epigenetic alterations identify a confluence of genetic vulnerabilities tied to opioid overdose. | Corradin O et al. | — | 2022 | → |
| Cross-Disorder Analysis of Genic and Regulatory Copy Number Variations in Bipolar Disorder, Schizophrenia, and Autism Spectrum Disorder. | Kushima I et al. | — | 2022 | → |
| Cross-tissue transcriptome-wide association studies identify susceptibility genes shared between schizophrenia and inflammatory bowel disease. | Uellendahl-Werth F et al. | — | 2022 | → |
| dbBIP: a comprehensive bipolar disorder database for genetic research. | Li X et al. | — | 2022 | → |
| Deep learning predicts DNA methylation regulatory variants in the human brain and elucidates the genetics of psychiatric disorders. | Zhou J et al. | — | 2022 | → |
| Deep proteomics identifies shared molecular pathway alterations in synapses of schizophrenia and bipolar disorder patients and mouse model | Aryal S et al. | — | 2022 | — |
| Depression and bipolar disorder subtypes differ in their genetic correlations with biological rhythms. | Sirignano L et al. | — | 2022 | → |
| Developmental disorders caused by haploinsufficiency of transcriptional regulators: a perspective based on cell fate determination. | Zug R | — | 2022 | → |
| Differences in mitochondrial DNA copy number between patients with bipolar I and II disorders. | Chung JK et al. | — | 2022 | → |
| Differences in subcortical brain volumes among patients with schizophrenia and bipolar disorder and healthy controls. | Ohi K et al. | — | 2022 | → |
| Differences in the genetic architecture of common and rare variants in childhood, persistent and late-diagnosed attention-deficit hyperactivity disorder. | Rajagopal VM et al. | — | 2022 | → |
| Differential genetic associations and expression of PAPST1/SLC35B2 in bipolar disorder and schizophrenia. | Uezato A et al. | — | 2022 | → |
| Dissecting the association between psychiatric disorders and neurological proteins: a genetic correlation and two-sample bidirectional Mendelian randomization study. | Huang H et al. | — | 2022 | → |
| Dissecting the genetic architecture of suicide attempt and repeated attempts in Korean patients with bipolar disorder using polygenic risk scores. | Lee D et al. | — | 2022 | → |
| Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors. | Mullins N et al. | — | 2022 | → |
| Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools. | Bahrami S et al. | — | 2022 | → |
| Dynamic proteomic and phosphoproteomic atlas of corticostriatal axons in neurodevelopment. | Dumrongprechachan V et al. | — | 2022 | → |
| Eating disorder symptoms and their associations with anthropometric and psychiatric polygenic scores. | Abdulkadir M et al. | — | 2022 | → |
| Effects of copy number variations on brain structure and risk for psychiatric illness: Large-scale studies from the ENIGMA working groups on CNVs. | Sønderby IE et al. | — | 2022 | → |
| Effects of polygenic risk for major mental disorders and cross-disorder on cortical complexity. | Schmitt S et al. | — | 2022 | → |
| EPIC: Inferring relevant cell types for complex traits by integrating genome-wide association studies and single-cell RNA sequencing. | Wang R et al. | — | 2022 | → |
| Epigenetic signatures relating to disease-associated genotypic burden in familial risk of bipolar disorder. | Hesam-Shariati S et al. | — | 2022 | → |
| Evaluating brain structure traits as endophenotypes using polygenicity and discoverability. | Matoba N et al. | — | 2022 | → |
| Examining the association between childhood autistic traits and adolescent hypomania: a longitudinal twin study. | Taylor MJ et al. | — | 2022 | → |
| Exome sequencing in bipolar disorder identifies AKAP11 as a risk gene shared with schizophrenia. | Palmer DS et al. | — | 2022 | → |
| Facial Emotion Recognition in Psychosis and Associations With Polygenic Risk for Schizophrenia: Findings From the Multi-Center EU-GEI Case-Control Study. | Tripoli G et al. | — | 2022 | → |
| Five Major Psychiatric Disorders and Alzheimer's Disease: A Bidirectional Mendelian Randomization Study. | Wei T et al. | — | 2022 | → |
| Functional genomic analysis delineates regulatory mechanisms of GWAS-identified bipolar disorder risk variants. | Chen R et al. | — | 2022 | → |
| Functional variant rs2270363 on 16p13.3 confers schizophrenia risk by regulating NMRAL1. | Wang J et al. | — | 2022 | → |
| Further delineation of phenotypic spectrum of SCN2A-related disorder. | Richardson R et al. | — | 2022 | → |
| Gene networks under circadian control exhibit diurnal organization in primate organs. | Li J et al. | — | 2022 | → |
| Gene Set Enrichment Analsyes Identify Pathways Involved in Genetic Risk for Diabetic Retinopathy. | Sobrin L et al. | — | 2022 | → |
| Genetic analysis of the human microglial transcriptome across brain regions, aging and disease pathologies. | Lopes KP et al. | — | 2022 | → |
| Genetic and environment effects on structural neuroimaging endophenotype for bipolar disorder: a novel molecular approach. | Hu B et al. | — | 2022 | → |
| Genetic and functional analyses implicate microRNA 499A in bipolar disorder development. | Tielke A et al. | — | 2022 | → |
| Genetic and psychosocial influence on the association between early childhood infections and later psychiatric disorders. | Debost JPG et al. | — | 2022 | → |
| Genetic architecture of 11 major psychiatric disorders at biobehavioral, functional genomic and molecular genetic levels of analysis. | Grotzinger AD et al. | — | 2022 | → |
| Genetic assortative mating for schizophrenia and bipolar disorder. | Jefsen OH et al. | — | 2022 | → |
| Genetic common variants associated with cerebellar volume and their overlap with mental disorders: a study on 33,265 individuals from the UK-Biobank. | Chambers T et al. | — | 2022 | → |
| Genetic correlation between female infertility and mental health and lifestyle factors: A linkage disequilibrium score regression study. | Ma M et al. | — | 2022 | → |
| Genetic correlation, pleiotropy, and causal associations between substance use and psychiatric disorder. | Jang SK et al. | — | 2022 | → |
| Genetic estimates of correlation and causality between blood-based biomarkers and psychiatric disorders. | Reay WR et al. | — | 2022 | → |
| Genetic evidence for a potential causal relationship between insomnia symptoms and suicidal behavior: a Mendelian randomization study. | Nassan M et al. | — | 2022 | → |
| Genetic heterogeneity and subtypes of major depression. | Nguyen TD et al. | — | 2022 | → |
| Genetic Liabilities Differentiating Bipolar Disorder, Schizophrenia, and Major Depressive Disorder, and Phenotypic Heterogeneity in Bipolar Disorder. | Richards AL et al. | — | 2022 | → |
| Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence. | Rao S et al. | — | 2022 | → |
| Genetic risk for psychiatric illness is associated with the number of hospitalizations of bipolar disorder patients. | Kalman JL et al. | — | 2022 | → |
| Genetics and Brain Transcriptomics of Completed Suicide. | Punzi G et al. | — | 2022 | → |
| Genetics-informed precision treatment formulation in schizophrenia and bipolar disorder. | Reay WR et al. | — | 2022 | → |
| Genetics of social anxiety disorder: a systematic review. | Baba A et al. | — | 2022 | → |
| Genetic variants associated with psychiatric disorders are enriched at epigenetically active sites in lymphoid cells. | Lynall ME et al. | — | 2022 | → |
| Genome-Transcriptome-Functional Connectivity-Cognition Link Differentiates Schizophrenia From Bipolar Disorder. | Chen J et al. | — | 2022 | → |
| Genome-wide analysis reveals genetic overlap between alcohol use behaviours, schizophrenia and bipolar disorder and identifies novel shared risk loci. | Wiström ED et al. | — | 2022 | → |
| Genome-Wide Association Study and Genetic Correlation Scan Provide Insights into Its Genetic Architecture of Sleep Health Score in the UK Biobank Cohort. | Yao Y et al. | — | 2022 | → |
| Genome-wide DNA methylation profiling in anorexia nervosa discordant identical twins. | Iranzo-Tatay C et al. | — | 2022 | → |
| Genomic and neuroimaging approaches to bipolar disorder. | Oraki Kohshour M et al. | — | 2022 | → |
| How genetic analysis may contribute to the understanding of avoidant/restrictive food intake disorder (ARFID). | Kennedy HL et al. | — | 2022 | → |
| Identification of genetic variants influencing methylation in brain with pleiotropic effects on psychiatric disorders. | Pineda-Cirera L et al. | — | 2022 | → |
| Identification of shared and differentiating genetic architecture for autism spectrum disorder, attention-deficit hyperactivity disorder and case subgroups. | Mattheisen M et al. | — | 2022 | → |
| Identifying enhancer properties associated with genetic risk for complex traits using regulome-wide association studies. | Casella AM et al. | — | 2022 | → |
| Identifying pleiotropic genes for complex phenotypes with summary statistics from a perspective of composite null hypothesis testing. | Wang T et al. | — | 2022 | → |
| Identifying the Common Genetic Basis of Antidepressant Response. | Pain O et al. | — | 2022 | → |
| Inhibition of glycogen synthase kinase 3 by lithium, a mechanism in search of specificity. | Chatterjee D et al. | — | 2022 | → |
| Integrative genomics reveals pathogenic mediator of valproate-induced neurodevelopmental disability. | Feleke R et al. | — | 2022 | → |
| Investigating genetic overlaps of the genetic factor differentiating schizophrenia from bipolar disorder with cognitive function and hippocampal volume. | Ohi K et al. | — | 2022 | → |
| Investigating the Impact of a Curse: Diseases, Population Isolation, Evolution and the Mother's Curse. | Kyrgiafini MA et al. | — | 2022 | → |
| Lithium as a Neuroprotective Agent for Bipolar Disorder: An Overview. | Ochoa ELM | — | 2022 | → |
| Mapping brain gene coexpression in daytime transcriptomes unveils diurnal molecular networks and deciphers perturbation gene signatures. | Wang N et al. | — | 2022 | → |
| Mapping Complex Brain Torque Components and Their Genetic Architecture and Phenomic Associations in 24,112 Individuals. | Zhao L et al. | — | 2022 | → |
| Mapping the expression of an ANK3 isoform associated with bipolar disorder in the human brain. | Holmgren A et al. | — | 2022 | → |
| Measuring mania-like elevated mood through amphetamine-induced 50-kHz ultrasonic vocalizations in rats. | Wöhr M | — | 2022 | → |
| Mendelian randomization analyses support causal relationships between brain imaging-derived phenotypes and risk of psychiatric disorders. | Guo J et al. | — | 2022 | → |
| Metabolic polygenic risk scores effect on antipsychotic-induced metabolic dysregulation: A longitudinal study in a first episode psychosis cohort. | Segura ÀG et al. | — | 2022 | → |
| Meta-imputation: An efficient method to combine genotype data after imputation with multiple reference panels. | Yu K et al. | — | 2022 | → |
| MicroRNA binding site variation is enriched in psychiatric disorders. | Geaghan MP et al. | — | 2022 | → |
| Multivariate genome-wide association study on tissue-sensitive diffusion metrics highlights pathways that shape the human brain. | Fan CC et al. | — | 2022 | → |
| Multivariate GWAS of psychiatric disorders and their cardinal symptoms reveal two dimensions of cross-cutting genetic liabilities. | Mallard TT et al. | — | 2022 | → |
| Neural Correlates of the Risk for Schizophrenia and Bipolar Disorder: A Meta-analysis of Structural and Functional Neuroimaging Studies. | Cattarinussi G et al. | — | 2022 | → |
| Neurobiological and behavioral mechanisms of circadian rhythm disruption in bipolar disorder: A critical multi-disciplinary literature review and agenda for future research from the ISBD task force on chronobiology. | McCarthy MJ et al. | — | 2022 | → |
| Neurocognition, functional outcome, and quality of life in remitted and non-remitted schizophrenia: A comparison with euthymic bipolar I disorder and a control group. | Jiménez-López E et al. | — | 2022 | → |
| Neurophysiology in psychosis: The quest for disease biomarkers. | Wang B et al. | — | 2022 | → |
| Neurostructural correlates of BDNF rs6265 genotype in youth bipolar disorder. | Kennedy KG et al. | — | 2022 | → |
| Novel loci and potential mechanisms of major depressive disorder, bipolar disorder, and schizophrenia. | Wang H et al. | — | 2022 | → |
| Novel open reading frames in human accelerated regions and transposable elements reveal new leads to understand schizophrenia and bipolar disorder. | Erady C et al. | — | 2022 | → |
| Overview of CAPICE-Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe-an EU Marie Skłodowska-Curie International Training Network. | Rajula HSR et al. | — | 2022 | → |
| Oxidative Stress and Psychiatric Disorders: Evidence from the Bidirectional Mendelian Randomization Study. | Lu Z et al. | — | 2022 | → |
| P2X7 Receptor-Related Genetic Mouse Models - Tools for Translational Research in Psychiatry. | Urbina-Treviño L et al. | — | 2022 | → |
| Patterns of Convergence and Divergence Between Bipolar Disorder Type I and Type II: Evidence From Integrative Genomic Analyses. | Huang Y et al. | — | 2022 | → |
| Pedigree-based study to identify GOLGB1 as a risk gene for bipolar disorder. | Liu FR et al. | — | 2022 | → |
| Perinatal depression is associated with a higher polygenic risk for major depressive disorder than non-perinatal depression. | Kiewa J et al. | — | 2022 | → |
| Peripheral lymphocyte signaling pathway deficiencies predict treatment response in first-onset drug-naïve schizophrenia. | Lago SG et al. | — | 2022 | → |
| Personality traits differentiate patients with bipolar disorder and healthy controls - A meta-analytic approach. | Hanke N et al. | — | 2022 | → |
| Phenotypes, mechanisms and therapeutics: insights from bipolar disorder GWAS findings. | Li M et al. | — | 2022 | → |
| Polygenic association with severity and long-term outcome in eating disorder cases. | Johansson T et al. | — | 2022 | → |
| Polygenic risk for mental disorder reveals distinct association profiles across social behaviour in the general population. | Schlag F et al. | — | 2022 | → |
| Population-level variation in enhancer expression identifies disease mechanisms in the human brain. | Dong P et al. | — | 2022 | → |
| Powerful and robust inference of complex phenotypes' causal genes with dependent expression quantitative loci by a median-based Mendelian randomization. | Jiang L et al. | — | 2022 | → |
| Precision medicine in mood disorders. | Serretti A | — | 2022 | → |
| Preliminary studies on apparent mendelian psychotic disorders in consanguineous families. | Kanwal A et al. | — | 2022 | → |
| Proteins associated with future suicide attempts in bipolar disorder: A large-scale biomarker discovery study. | Sandberg JV et al. | — | 2022 | → |
| Psychiatric manifestations of rare variation in medically actionable genes: a PheWAS approach. | Feng YA et al. | — | 2022 | → |
| Psychiatric polygenic risk scores: Child and adolescent psychiatrists' knowledge, attitudes, and experiences. | Pereira S et al. | — | 2022 | → |
| Psychiatric traits and intracerebral hemorrhage: A Mendelian randomization study. | Wang Q et al. | — | 2022 | → |
| Pupil size and pupillary light reflex in early infancy: heritability and link to genetic liability to schizophrenia. | Portugal AM et al. | — | 2022 | → |
| Recent Developments in Autism Genetic Research: A Scientometric Review from 2018 to 2022. | Lim M et al. | — | 2022 | → |
| Reconceptualizing schizophrenia in the Hierarchical Taxonomy Of Psychopathology (HiTOP). | Kotov R et al. | — | 2022 | → |
| Reconstructing SNP allele and genotype frequencies from GWAS summary statistics. | Yang Z et al. | — | 2022 | → |
| Regulatory Variant rs2535629 in ITIH3 Intron Confers Schizophrenia Risk By Regulating CTCF Binding and SFMBT1 Expression. | Li Y et al. | — | 2022 | → |
| Regulatory variants at 2q33.1 confer schizophrenia risk by modulating distal gene TYW5 expression. | Li S et al. | — | 2022 | → |
| Research Status in Clinical Practice Regarding Pediatric and Adolescent Bipolar Disorders. | Liu L et al. | — | 2022 | → |
| Risk factor profiles for depression following childbirth or a chronic disease diagnosis: case-control study. | Jermy BS et al. | — | 2022 | → |
| Role of Polygenic Risk Score in the Familial Transmission of Bipolar Disorder in Youth. | Birmaher B et al. | — | 2022 | → |
| scGWAS: landscape of trait-cell type associations by integrating single-cell transcriptomics-wide and genome-wide association studies. | Jia P et al. | — | 2022 | → |
| Schizophrenia and Bipolar Polygenic Risk Scores in Relation to Intracranial Volume. | de Zwarte SMC et al. | — | 2022 | → |
| Sensitive period-regulating genetic pathways and exposure to adversity shape risk for depression. | Zhu Y et al. | — | 2022 | → |
| Serum concentration of zinc is elevated in clinically stable bipolar disorder patients. | Jonsson BH et al. | — | 2022 | → |
| Sex differences in gene regulatory networks during mid-gestational brain development. | de Toledo VHC et al. | — | 2022 | → |
| Sex-specific genetic association between psychiatric disorders and cognition, behavior and brain imaging in children and adults. | Gui Y et al. | — | 2022 | → |
| Shared genetic influences on resting-state functional networks of the brain. | P O F T Guimarães J et al. | — | 2022 | → |
| Shared genetic links between frontotemporal dementia and psychiatric disorders. | Li C et al. | — | 2022 | → |
| Shared mechanisms across the major psychiatric and neurodegenerative diseases. | Wingo TS et al. | — | 2022 | → |
| Single nucleus multi-omics identifies human cortical cell regulatory genome diversity. | Luo C et al. | — | 2022 | → |
| Socioeconomic status, individual behaviors and risk for mental disorders: A Mendelian randomization study. | Cai J et al. | — | 2022 | → |
| Sodium-calcium exchanger-3 regulates pain "wind-up": From human psychophysics to spinal mechanisms. | Trendafilova T et al. | — | 2022 | → |
| Spatiotemporal and genetic regulation of A-to-I editing throughout human brain development. | Dredge WH et al. | — | 2022 | → |
| Stratification of individuals with lifetime depression and low wellbeing in the UK Biobank. | Fabbri C et al. | — | 2022 | → |
| Structural network alterations in focal and generalized epilepsy assessed in a worldwide ENIGMA study follow axes of epilepsy risk gene expression. | Larivière S et al. | — | 2022 | → |
| Systematic Review: Molecular Studies of Common Genetic Variation in Child and Adolescent Psychiatric Disorders. | Akingbuwa WA et al. | — | 2022 | → |
| Systemic inflammatory regulators and 7 major psychiatric disorders: A two-sample Mendelian randomization study. | Chen X et al. | — | 2022 | → |
| Ten challenges for clinical translation in psychiatric genetics. | Derks EM et al. | — | 2022 | → |
| The addiction risk factor: A unitary genetic vulnerability characterizes substance use disorders and their associations with common correlates. | Hatoum AS et al. | — | 2022 | → |
| The Australian Genetics of Depression Study: New Risk Loci and Dissecting Heterogeneity Between Subtypes. | Mitchell BL et al. | — | 2022 | → |
| The benefit of diagnostic whole genome sequencing in schizophrenia and other psychotic disorders. | Alkelai A et al. | — | 2022 | → |
| The consequences of a year of the COVID-19 pandemic for the mental health of young adult twins in England and Wales. | Rimfeld K et al. | — | 2022 | → |
| The Current Progress of Psychiatric Genomics. | Nishioka M | — | 2022 | → |
| The detrimental effects of smoking on the course and outcome in adults with bipolar disorder-A narrative review. | Grunze A et al. | — | 2022 | → |
| The effect of polygenic risk scores for major depressive disorder, bipolar disorder and schizophrenia on morphological brain measures: A systematic review of the evidence. | Cattarinussi G et al. | — | 2022 | → |
| The Effects of Plasma Homocysteine Level on the Risk of Three Major Psychiatric Disorders: A Mendelian Randomization Study. | Yu J et al. | — | 2022 | → |
| The genetic architecture of pneumonia susceptibility implicates mucin biology and a relationship with psychiatric illness. | Reay WR et al. | — | 2022 | → |
| The genetics of bipolar disorder with obesity and type 2 diabetes. | Miola A et al. | — | 2022 | → |
| The next 10 years of behavioural genomic research. | Plomin R | — | 2022 | → |
| The shared genetic basis of mood instability and psychiatric disorders: A cross-trait genome-wide association analysis. | Hindley G et al. | — | 2022 | → |
| Thirteen Independent Genetic Loci Associated with Preserved Processing Speed in a Study of Cognitive Resilience in 330,097 Individuals in the UK Biobank. | Fitzgerald J et al. | — | 2022 | → |
| Thirty novel sequence variants impacting human intracranial volume. | Nawaz MS et al. | — | 2022 | → |
| Transcriptional programs regulating neuronal differentiation are disrupted in DLG2 knockout human embryonic stem cells and enriched for schizophrenia and related disorders risk variants. | Sanders B et al. | — | 2022 | → |
| Ubiquitin Binding Protein 2-Like (UBAP2L): is it so NICE After All? | Guerber L et al. | — | 2022 | → |
| Using DNA to predict behaviour problems from preschool to adulthood. | Gidziela A et al. | — | 2022 | → |
| Using Stem Cell Models to Explore the Genetics Underlying Psychiatric Disorders: Linking Risk Variants, Genes, and Biology in Brain Disease. | Brennand KJ | — | 2022 | → |
| Validity and utility of Hierarchical Taxonomy of Psychopathology (HiTOP): III. Emotional dysfunction superspectrum. | Watson D et al. | — | 2022 | → |
| What we learn about bipolar disorder from large-scale neuroimaging: Findings and future directions from the ENIGMA Bipolar Disorder Working Group. | Ching CRK et al. | — | 2022 | → |
| Zika virus-induced TNF-α signaling dysregulates expression of neurologic genes associated with psychiatric disorders. | Kung PL et al. | — | 2022 | → |
| 30 years of repeat expansion disorders: What have we learned and what are the remaining challenges? | Depienne C et al. | — | 2021 | → |
| 3D promoter architecture re-organization during iPSC-derived neuronal cell differentiation implicates target genes for neurodevelopmental disorders. | Su C et al. | — | 2021 | → |
| A Comprehensive Evaluation of Cross-Omics Blood-Based Biomarkers for Neuropsychiatric Disorders. | Song W et al. | — | 2021 | → |
| A comprehensive gene-centric pleiotropic association analysis for 14 psychiatric disorders with GWAS summary statistics. | Lu H et al. | — | 2021 | → |
| A Comprehensive Review on the Role of Non-Coding RNAs in the Pathophysiology of Bipolar Disorder. | Ghafouri-Fard S et al. | — | 2021 | → |
| Advances toward precision medicine for bipolar disorder: mechanisms & molecules. | Haggarty SJ et al. | — | 2021 | → |
| Akt-mTOR hypoactivity in bipolar disorder gives rise to cognitive impairments associated with altered neuronal structure and function. | Vanderplow AM et al. | — | 2021 | → |
| A linkage and exome study of multiplex families with bipolar disorder implicates rare coding variants of ANK3 and additional rare alleles at 10q11-q21. | Toma C et al. | — | 2021 | → |
| Alu element in the RNA binding motif protein, X-linked 2 (RBMX2) gene found to be linked to bipolar disorder. | Laine P et al. | — | 2021 | → |
| A missense variant in NDUFA6 confers schizophrenia risk by affecting YY1 binding and NAGA expression. | Li Y et al. | — | 2021 | → |
| ANK3 Gene Polymorphism Rs10994336 Influences Executive Functions by Modulating Methylation in Patients With Bipolar Disorder. | Tang L et al. | — | 2021 | → |
| Ankyrin-G Heterozygous Knockout Mice Display Increased Sensitivity to Social Defeat Stress. | Cordner ZA et al. | — | 2021 | → |
| "Apples and pears are similar, but still different things." Bipolar disorder and schizophrenia- discrete disorders or just dimensions ? | Grunze H et al. | — | 2021 | → |
| Are psychiatric disorders risk factors for COVID-19 susceptibility and severity? a two-sample, bidirectional, univariable, and multivariable Mendelian Randomization study. | Luykx JJ et al. | — | 2021 | → |
| Association Between Genetic Risk for Psychiatric Disorders and the Probability of Living in Urban Settings. | Maxwell JM et al. | — | 2021 | → |
| Association between polygenic propensity for psychiatric disorders and nutrient intake. | Hunjan AK et al. | — | 2021 | → |
| Association of accelerometer-derived sleep measures with lifetime psychiatric diagnoses: A cross-sectional study of 89,205 participants from the UK Biobank. | Wainberg M et al. | — | 2021 | → |
| Association of Antihypertensive Drug Target Genes With Psychiatric Disorders: A Mendelian Randomization Study. | Chauquet S et al. | — | 2021 | → |
| Association of genetic liability for psychiatric disorders with accelerometer-assessed physical activity in the UK Biobank. | Dennison CA et al. | — | 2021 | → |
| Associations between patterns in comorbid diagnostic trajectories of individuals with schizophrenia and etiological factors. | Krebs MD et al. | — | 2021 | → |
| Associations Between Schizophrenia Polygenic Liability, Symptom Dimensions, and Cognitive Ability in Schizophrenia. | Legge SE et al. | — | 2021 | → |
| Bipolar Depression: A Historical Perspective of the Current Concept, with a Focus on Future Research. | Martino DJ et al. | — | 2021 | → |
| Bipolar disorder and cannabis use: A bidirectional two-sample Mendelian randomization study. | Jefsen OH et al. | — | 2021 | → |
| Brain gene co-expression networks link complement signaling with convergent synaptic pathology in schizophrenia. | Kim M et al. | — | 2021 | → |
| Brain regionalization by Polycomb-group proteins and chromatin accessibility. | Eto H et al. | — | 2021 | → |
| Brain-trait-associated variants impact cell-type-specific gene regulation during neurogenesis. | Aygün N et al. | — | 2021 | → |
| Can polygenic risk scores help identify pediatric bipolar spectrum and related disorders?: A systematic review. | Biederman J et al. | — | 2021 | → |
| Cascading epigenomic analysis for identifying disease genes from the regulatory landscape of GWAS variants. | Ng B et al. | — | 2021 | → |
| Cataloging recent advances in epigenetic alterations in major mental disorders and autism. | Abdolmaleky HM et al. | — | 2021 | → |
| Causal associations of intelligence with schizophrenia and bipolar disorder: A Mendelian randomization analysis. | Ohi K et al. | — | 2021 | → |
| Causal inference for heritable phenotypic risk factors using heterogeneous genetic instruments. | Wang J et al. | — | 2021 | → |
| Cell-type-specific effects of genetic variation on chromatin accessibility during human neuronal differentiation. | Liang D et al. | — | 2021 | → |
| Cell-Type-Specific Gene Modules Related to the Regional Homogeneity of Spontaneous Brain Activity and Their Associations With Common Brain Disorders. | Shen J et al. | — | 2021 | → |
| Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations. | Panyard DJ et al. | — | 2021 | → |
| Characterisation of age and polarity at onset in bipolar disorder. | Kalman JL et al. | — | 2021 | → |
| Characterising the shared genetic determinants of bipolar disorder, schizophrenia and risk-taking. | Hindley G et al. | — | 2021 | → |
| Characterizing the Genetic Overlap Between Psychiatric Disorders and Sleep-Related Phenotypes. | O'Connell KS et al. | — | 2021 | → |
| Chronic lithium treatment alters the excitatory/ inhibitory balance of synaptic networks and reduces mGluR5-PKC signalling in mouse cortical neurons. | Khayachi A et al. | — | 2021 | → |
| Clinical and genetic differences between bipolar disorder type 1 and 2 in multiplex families. | Guzman-Parra J et al. | — | 2021 | → |
| Combined change of behavioral traits for domestication and gene-networks in mice selectively bred for active tameness. | Matsumoto Y et al. | — | 2021 | → |
| Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients. | Schubert KO et al. | — | 2021 | → |
| Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology. | van Rheenen W et al. | — | 2021 | → |
| Contribution of birth weight to mental health, cognitive and socioeconomic outcomes: two-sample Mendelian randomisation. | Orri M et al. | — | 2021 | → |
| Convergence and Divergence in the Genetics of Psychiatric Disorders From Pathways to Developmental Stages. | Shohat S et al. | — | 2021 | → |
| Convergent genomic and pharmacological evidence of PI3K/GSK3 signaling alterations in neurons from schizophrenia patients. | Stertz L et al. | — | 2021 | → |
| Cooperation of LIM domain-binding 2 (LDB2) with EGR in the pathogenesis of schizophrenia. | Ohnishi T et al. | — | 2021 | → |
| Cooperative Studies Program (CSP) #572: A Study of Serious Mental Illness in Veterans as a Pathway to personalized medicine in Schizophrenia and Bipolar Illness. | Harvey PD et al. | — | 2021 | → |
| Could Polygenic Risk Scores Be Useful in Psychiatry?: A Review. | Murray GK et al. | — | 2021 | → |
| Decreased DNA methylation at promoters and gene-specific neuronal hypermethylation in the prefrontal cortex of patients with bipolar disorder. | Bundo M et al. | — | 2021 | → |
| Deep transcriptome sequencing of subgenual anterior cingulate cortex reveals cross-diagnostic and diagnosis-specific RNA expression changes in major psychiatric disorders. | Akula N et al. | — | 2021 | → |
| Detecting local genetic correlations with scan statistics. | Guo H et al. | — | 2021 | → |
| Developmental Profile of Psychiatric Risk Associated With Voltage-Gated Cation Channel Activity. | Clifton NE et al. | — | 2021 | → |
| Diacylglycerol lipase alpha in astrocytes is involved in maternal care and affective behaviors. | Schuele LL et al. | — | 2021 | → |
| Differentiating between bipolar and unipolar depression using prefrontal activation patterns: Promising results from functional near infrared spectroscopy (fNIRS) findings. | Feng K et al. | — | 2021 | → |
| Discordant associations of educational attainment with ASD and ADHD implicate a polygenic form of pleiotropy. | Verhoef E et al. | — | 2021 | → |
| Dissecting polygenic signals from genome-wide association studies on human behaviour. | Abdellaoui A et al. | — | 2021 | → |
| Dissect Relationships Between Gene Co-expression and Functional Connectivity in Human Brain. | Zhang X et al. | — | 2021 | → |
| Distinct effect of prenatal and postnatal brain expression across 20 brain disorders and anthropometric social traits: a systematic study of spatiotemporal modularity. | Jia P et al. | — | 2021 | → |
| Duration of Untreated Psychosis in First-Episode Psychosis is not Associated With Common Genetic Variants for Major Psychiatric Conditions: Results From the Multi-Center EU-GEI Study. | Ajnakina O et al. | — | 2021 | → |
| E-MAGMA: an eQTL-informed method to identify risk genes using genome-wide association study summary statistics. | Gerring ZF et al. | — | 2021 | → |
| Epigenetic Element-Based Transcriptome-Wide Association Study Identifies Novel Genes for Bipolar Disorder. | Yao S et al. | — | 2021 | → |
| Epigenetic marks in suicide: a review. | Ramos-Rosales DF et al. | — | 2021 | → |
| Evidence for Reduced Long-Term Potentiation-Like Visual Cortical Plasticity in Schizophrenia and Bipolar Disorder. | Valstad M et al. | — | 2021 | → |
| Examining sex differences in neurodevelopmental and psychiatric genetic risk in anxiety and depression. | Martin J et al. | — | 2021 | → |
| Exploring brain insulin resistance in adults with bipolar depression using extracellular vesicles of neuronal origin. | Mansur RB et al. | — | 2021 | → |
| Extensive bidirectional genetic overlap between bipolar disorder and cardiovascular disease phenotypes. | Rødevand L et al. | — | 2021 | → |
| From genetics to systems biology of stress-related mental disorders. | Dalvie S et al. | — | 2021 | → |
| Functional and behavioral effects of de novo mutations in calcium-related genes in patients with bipolar disorder. | Nakamura T et al. | — | 2021 | → |
| Functional brain defects in a mouse model of a chromosomal t(1;11) translocation that disrupts DISC1 and confers increased risk of psychiatric illness. | Bonneau M et al. | — | 2021 | → |
| Functional patient-derived cellular models for neuropsychiatric drug discovery. | Lago SG et al. | — | 2021 | → |
| Gene-environment correlations and causal effects of childhood maltreatment on physical and mental health: a genetically informed approach. | Warrier V et al. | — | 2021 | → |
| Genes influenced by MEF2C contribute to neurodevelopmental disease via gene expression changes that affect multiple types of cortical excitatory neurons. | Cosgrove D et al. | — | 2021 | → |
| Genetically predicted bipolar disorder is causally associated with an increased risk of breast cancer: a two-sample Mendelian randomization analysis. | Peng H et al. | — | 2021 | → |
| Genetically predicted education attainment in relation to somatic and mental health. | Yuan S et al. | — | 2021 | → |
| Genetic and clinical analyses of psychosis spectrum symptoms in a large multiethnic youth cohort reveal significant link with ADHD. | Olde Loohuis LM et al. | — | 2021 | → |
| Genetic and clinical characteristics of treatment-resistant depression using primary care records in two UK cohorts. | Fabbri C et al. | — | 2021 | → |
| Genetic architecture of Tourette syndrome: our current understanding. | Domènech L et al. | — | 2021 | → |
| Genetic association of FMRP targets with psychiatric disorders. | Clifton NE et al. | — | 2021 | → |
| Genetic contributions to bipolar disorder: current status and future directions. | O'Connell KS et al. | — | 2021 | → |
| Genetic factors influencing a neurobiological substrate for psychiatric disorders. | Andlauer TFM et al. | — | 2021 | → |
| Genetic neuroimaging of bipolar disorder: a systematic 2017-2020 update. | Janiri D et al. | — | 2021 | → |
| Genetic overlap and causal associations between smoking behaviours and mental health. | Barkhuizen W et al. | — | 2021 | → |
| Genetic Predisposition Between COVID-19 and Four Mental Illnesses: A Bidirectional, Two-Sample Mendelian Randomization Study. | Liu N et al. | — | 2021 | → |
| Genetic predisposition to alcohol dependence: The combined role of polygenic risk to general psychopathology and to high alcohol consumption. | Facal F et al. | — | 2021 | → |
| Genetic underpinnings of affective temperaments: a pilot GWAS investigation identifies a new genome-wide significant SNP for anxious temperament in ADGRB3 gene. | Gonda X et al. | — | 2021 | → |
| Genetic underpinnings of sociability in the general population. | Bralten J et al. | — | 2021 | → |
| Genetic Variation in the ASTN2 Locus in Cardiovascular, Metabolic and Psychiatric Traits: Evidence for Pleiotropy Rather Than Shared Biology. | Burt O et al. | — | 2021 | → |
| Genetic Variations Associated with Long-Term Treatment Response in Bipolar Depression. | Anmella G et al. | — | 2021 | → |
| GenNet framework: interpretable deep learning for predicting phenotypes from genetic data. | van Hilten A et al. | — | 2021 | → |
| Genome-wide association analyses of post-traumatic stress disorder and its symptom subdomains in the Million Veteran Program. | Stein MB et al. | — | 2021 | → |
| Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease. | DeMichele-Sweet MAA et al. | — | 2021 | → |
| Genome-Wide Association Studies of Schizophrenia and Bipolar Disorder in a Diverse Cohort of US Veterans. | Bigdeli TB et al. | — | 2021 | → |
| Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. | Mullins N et al. | — | 2021 | → |
| Genome-wide association study of patients with a severe major depressive episode treated with electroconvulsive therapy. | Clements CC et al. | — | 2021 | → |
| Genome-wide association study of suicidal behaviour severity in mood disorders. | Zai CC et al. | — | 2021 | → |
| Genome-wide association study reveals new insights into the heritability and genetic correlates of developmental dyslexia. | Gialluisi A et al. | — | 2021 | → |
| Genomic perspectives on the circadian clock hypothesis of psychiatric disorders. | von Schantz M et al. | — | 2021 | → |
| Genomic relationships across psychiatric disorders including substance use disorders. | Abdellaoui A et al. | — | 2021 | → |
| Gut Microbiota and Psychiatric Disorders: A Two-Sample Mendelian Randomization Study. | Ni JJ et al. | — | 2021 | → |
| GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression. | Wu Y et al. | — | 2021 | → |
| Higher polygenic risk scores for schizophrenia may be suggestive of treatment non-response in major depressive disorder. | Fanelli G et al. | — | 2021 | → |
| How rare and common risk variation jointly affect liability for autism spectrum disorder. | Klei L et al. | — | 2021 | → |
| Identification of Gene Loci That Overlap Between Mental Disorders and Poor Prognosis of Cancers. | Xu JL et al. | — | 2021 | → |
| Identification of pleiotropy at the gene level between psychiatric disorders and related traits. | Polushina T et al. | — | 2021 | → |
| Identification of Rare Mutations of Two Presynaptic Cytomatrix Genes <i>BSN</i> and <i>PCLO</i> in Schizophrenia and Bipolar Disorder. | Chen CH et al. | — | 2021 | → |
| Identification of transdiagnostic psychiatric disorder subtypes using unsupervised learning. | Pelin H et al. | — | 2021 | → |
| Identifying age-specific gene signatures of the human cerebral cortex with joint analysis of transcriptomes and functional connectomes. | Zhao X et al. | — | 2021 | → |
| Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS. | Peyrot WJ et al. | — | 2021 | → |
| Increasing the resolution and precision of psychiatric genome-wide association studies by re-imputing summary statistics using a large, diverse reference panel. | Chatzinakos C et al. | — | 2021 | → |
| Independent replications and integrative analyses confirm TRANK1 as a susceptibility gene for bipolar disorder. | Li W et al. | — | 2021 | → |
| Inflammation and disease modification in bipolar disorders: Priority avenues for future research. | Gill H et al. | — | 2021 | → |
| Influence of polygenic risk scores for schizophrenia and resilience on the cognition of individuals at-risk for psychosis. | He Q et al. | — | 2021 | → |
| Integration of genetic, transcriptomic, and clinical data provides insight into 16p11.2 and 22q11.2 CNV genes. | Vysotskiy M et al. | — | 2021 | → |
| Integrative analysis of genome-wide association studies identifies novel loci associated with neuropsychiatric disorders. | Yao X et al. | — | 2021 | → |
| Integrative Genomic-Epigenomic Analysis of Clozapine-Treated Patients with Refractory Psychosis. | Mayén-Lobo YG et al. | — | 2021 | → |
| Intelligence decline across major depressive disorder, bipolar disorder, and schizophrenia. | Ohi K et al. | — | 2021 | → |
| Interpreting type 1 diabetes risk with genetics and single-cell epigenomics. | Chiou J et al. | — | 2021 | → |
| Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder. | Jia X et al. | — | 2021 | → |
| Investigating the causal relationship between allergic disease and mental health. | Budu-Aggrey A et al. | — | 2021 | → |
| Investigation of genetic loci shared between bipolar disorder and risk-taking propensity: potential implications for pharmacological interventions. | Pisanu C et al. | — | 2021 | → |
| Investigation of glycaemic traits in psychiatric disorders using Mendelian randomisation revealed a causal relationship with anorexia nervosa. | Adams DM et al. | — | 2021 | → |
| Is there a shared genetic basis and causal relationship between polycystic ovary syndrome and psychiatric disorders: evidence from a comprehensive genetic analysis. | Jiang X et al. | — | 2021 | → |
| Kleine-Levin syndrome is associated with birth difficulties and genetic variants in the <i>TRANK1</i> gene loci. | Ambati A et al. | — | 2021 | → |
| Large-scale collaboration in ENIGMA-EEG: A perspective on the meta-analytic approach to link neurological and psychiatric liability genes to electrophysiological brain activity. | Smit DJA et al. | — | 2021 | → |
| Leveraging both individual-level genetic data and GWAS summary statistics increases polygenic prediction. | Albiñana C et al. | — | 2021 | → |
| Mendelian randomization studies of brain MRI yield insights into the pathogenesis of neuropsychiatric disorders. | Song W et al. | — | 2021 | → |
| Methylome-wide change associated with response to electroconvulsive therapy in depressed patients. | Sirignano L et al. | — | 2021 | → |
| Modeling SARS-CoV-2 infection in individuals with opioid use disorder with brain organoids. | Willner MJ et al. | — | 2021 | → |
| Molecular and neurocircuitry mechanisms of social avoidance. | Gellner AK et al. | — | 2021 | → |
| Molecular characterization of the stress network in individuals at risk for schizophrenia. | Meijer M et al. | — | 2021 | → |
| Mood Stabilizers in Psychiatric Disorders and Mechanisms Learnt from In Vitro Model Systems. | Nayak R et al. | — | 2021 | → |
| Motivating and Discouraging Factors for Bipolar Patient Participation in Genomic Research. | Vallender EJ et al. | — | 2021 | → |
| Multi-omics analyses of cognitive traits and psychiatric disorders highlights brain-dependent mechanisms. | Korologou-Linden R et al. | — | 2021 | → |
| Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction. | Karlsson Linnér R et al. | — | 2021 | → |
| [Neurogenetics of schizophrenia: findings from studies based on data sharing and global partnerships]. | Adorjan K et al. | — | 2021 | → |
| Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders. | Hu B et al. | — | 2021 | → |
| Neuropsychiatric disorders: An immunological perspective. | Aw E et al. | — | 2021 | → |
| Neuropsychiatric Genetics of Psychosis in the Mexican Population: A Genome-Wide Association Study Protocol for Schizophrenia, Schizoaffective, and Bipolar Disorder Patients and Controls. | Camarena B et al. | — | 2021 | → |
| Neurotrophin receptor activation rescues cognitive and synaptic abnormalities caused by hemizygosity of the psychiatric risk gene Cacna1c. | Tigaret CM et al. | — | 2021 | → |
| New Evidence of Gut Microbiota Involvement in the Neuropathogenesis of Bipolar Depression by <i>TRANK1</i> Modulation: Joint Clinical and Animal Data. | Lai J et al. | — | 2021 | → |
| Novel lincRNA Discovery and Tissue-Specific Gene Expression across 30 Normal Human Tissues. | Chen X et al. | — | 2021 | → |
| Novel Risk Loci Associated With Genetic Risk for Bipolar Disorder Among Han Chinese Individuals: A Genome-Wide Association Study and Meta-analysis. | Li HJ et al. | — | 2021 | → |
| One size does not fit all. Genomics differentiates among anorexia nervosa, bulimia nervosa, and binge-eating disorder. | Hübel C et al. | — | 2021 | → |
| Overexpression of CD47 is associated with brain overgrowth and 16p11.2 deletion syndrome. | Li J et al. | — | 2021 | → |
| Oxytocin-pathway polygenic scores for severe mental disorders and metabolic phenotypes in the UK Biobank. | Winterton A et al. | — | 2021 | → |
| Pharmacogenomics of Lithium Response in Bipolar Disorder. | Vecera CM et al. | — | 2021 | → |
| Phenotypically independent profiles relevant to mental health are genetically correlated. | Roelfs D et al. | — | 2021 | → |
| Placental genomic risk scores and early neurodevelopmental outcomes. | Ursini G et al. | — | 2021 | → |
| Pleiotropy and Cross-Disorder Genetics Among Psychiatric Disorders. | Lee PH et al. | — | 2021 | → |
| Polygenic Heterogeneity Across Obsessive-Compulsive Disorder Subgroups Defined by a Comorbid Diagnosis. | Strom NI et al. | — | 2021 | → |
| Polygenic overlap and shared genetic loci between loneliness, severe mental disorders, and cardiovascular disease risk factors suggest shared molecular mechanisms. | Rødevand L et al. | — | 2021 | → |
| Polygenic risk for autism, attention-deficit hyperactivity disorder, schizophrenia, major depressive disorder, and neuroticism is associated with the experience of childhood abuse. | Ratanatharathorn A et al. | — | 2021 | → |
| Polygenic risk score as clinical utility in psychiatry: a clinical viewpoint. | Ikeda M et al. | — | 2021 | → |
| Polygenic risk score for bipolar disorder associates with divergent thinking and brain structures in the prefrontal cortex. | Takeuchi H et al. | — | 2021 | → |
| Polygenic Risk Scores Differentiating Schizophrenia From Bipolar Disorder Are Associated With Premorbid Intelligence in Schizophrenia Patients and Healthy Subjects. | Ohi K et al. | — | 2021 | → |
| Polygenic risk scores for major psychiatric and neurodevelopmental disorders contribute to sleep disturbance in childhood: Adolescent Brain Cognitive Development (ABCD) Study. | Ohi K et al. | — | 2021 | → |
| Polygenic Scores for ADHD: A Meta-Analysis. | Li JJ et al. | — | 2021 | → |
| Positional cloning and comprehensive mutation analysis of a Japanese family with lithium-responsive bipolar disorder identifies a novel DOCK5 mutation. | Umehara H et al. | — | 2021 | → |
| Possible Modulatory Role of ARC Gene Variants in Mood Disorders. | Crisafulli C et al. | — | 2021 | → |
| Post-partum psychosis and its association with bipolar disorder in the UK: a case-control study using polygenic risk scores. | Di Florio A et al. | — | 2021 | → |
| Posttranslational modifications & lithium's therapeutic effect-Potential biomarkers for clinical responses in psychiatric & neurodegenerative disorders. | Khayachi A et al. | — | 2021 | → |
| Powerful gene-based testing by integrating long-range chromatin interactions and knockoff genotypes. | Ma S et al. | — | 2021 | → |
| Precision medicine for mood disorders: objective assessment, risk prediction, pharmacogenomics, and repurposed drugs. | Le-Niculescu H et al. | — | 2021 | → |
| Predicting clinical outcome to specialist multimodal inpatient treatment in patients with treatment resistant depression. | Taylor RW et al. | — | 2021 | → |
| Prediction of lithium response using genomic data. | Stone W et al. | — | 2021 | → |
| Proteome-wide Association Study Provides Insights Into the Genetic Component of Protein Abundance in Psychiatric Disorders. | Liu J et al. | — | 2021 | → |
| Rare germline variants in individuals diagnosed with schizophrenia within multiplex families. | Li S et al. | — | 2021 | → |
| Reduced adult neurogenesis is associated with increased macrophages in the subependymal zone in schizophrenia. | Weissleder C et al. | — | 2021 | → |
| Replicating extensive brain structural heterogeneity in individuals with schizophrenia and bipolar disorder. | Wolfers T et al. | — | 2021 | → |
| Residential green space structures are associated with a lower risk of bipolar disorder: A nationwide population-based study in Taiwan. | Chang HT et al. | — | 2021 | → |
| Risk Factors, Clinical Features, and Polygenic Risk Scores in Schizophrenia and Schizoaffective Disorder Depressive-Type. | Dennison CA et al. | — | 2021 | → |
| Risk in Relatives, Heritability, SNP-Based Heritability, and Genetic Correlations in Psychiatric Disorders: A Review. | Baselmans BML et al. | — | 2021 | → |
| Role of DNA Methylation in Mediating Genetic Risk of Psychiatric Disorders. | Starnawska A et al. | — | 2021 | → |
| Role of FAT1 in health and disease. | Peng Z et al. | — | 2021 | → |
| SATB2-LEMD2 interaction links nuclear shape plasticity to regulation of cognition-related genes. | Feurle P et al. | — | 2021 | → |
| Schizophrenia polygenic risk scores in youth mental health: preliminary associations with diagnosis, clinical stage and functioning. | Crouse JJ et al. | — | 2021 | → |
| SERINC2 increases the risk of bipolar disorder in the Chinese population. | Yang D et al. | — | 2021 | → |
| Sex differences in anxiety and depression in children with attention deficit hyperactivity disorder: Investigating genetic liability and comorbidity. | Martin J et al. | — | 2021 | → |
| Sex differences in the genetic regulation of the blood transcriptome response to glucocorticoid receptor activation. | Moore SR et al. | — | 2021 | → |
| Shared heritability of human face and brain shape. | Naqvi S et al. | — | 2021 | → |
| Shared sets of correlated polygenic risk scores and voxel-wise grey matter across multiple traits identified via bi-clustering. | Rahaman MA et al. | — | 2021 | → |
| Shared transethnic genetic basis of panic disorder and psychiatric and related intermediate phenotypes. | Ohi K et al. | — | 2021 | → |
| Single-cell epigenomics reveals mechanisms of human cortical development. | Ziffra RS et al. | — | 2021 | → |
| Single-nucleus transcriptome analysis reveals cell-type-specific molecular signatures across reward circuitry in the human brain. | Tran MN et al. | — | 2021 | → |
| Smoking and the risk for bipolar disorder: evidence from a bidirectional Mendelian randomisation study. | Vermeulen JM et al. | — | 2021 | → |
| SnapHiC: a computational pipeline to identify chromatin loops from single-cell Hi-C data. | Yu M et al. | — | 2021 | → |
| Socioeconomic Deprivation Index Is Associated With Psychiatric Disorders: An Observational and Genome-wide Gene-by-Environment Interaction Analysis in the UK Biobank Cohort. | Ye J et al. | — | 2021 | → |
| Spatial Expression Pattern of ZNF391 Gene in the Brains of Patients With Schizophrenia, Bipolar Disorders or Major Depressive Disorder Identifies New Cross-Disorder Biotypes: A Trans-Diagnostic, Top-Down Approach. | Ren H et al. | — | 2021 | → |
| SUPERGNOVA: local genetic correlation analysis reveals heterogeneous etiologic sharing of complex traits. | Zhang Y et al. | — | 2021 | → |
| Systematic analysis of exonic germline and postzygotic de novo mutations in bipolar disorder. | Nishioka M et al. | — | 2021 | → |
| Targeting synaptic plasticity in schizophrenia: insights from genomic studies. | Mould AW et al. | — | 2021 | → |
| TCF7L2 lncRNA: a link between bipolar disorder and body mass index through glucocorticoid signaling. | Liu D et al. | — | 2021 | → |
| Testing and estimation of X-chromosome SNP effects: Impact of model assumptions. | Song Y et al. | — | 2021 | → |
| The 2020 Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders. | Malhi GS et al. | — | 2021 | → |
| The association of polygenic risk for schizophrenia, bipolar disorder, and depression with neural connectivity in adolescents and young adults: examining developmental and sex differences. | Meyers JL et al. | — | 2021 | → |
| The Babytwins Study Sweden (BATSS): A Multi-Method Infant Twin Study of Genetic and Environmental Factors Influencing Infant Brain and Behavioral Development. | Falck-Ytter T et al. | — | 2021 | → |
| The conserved ASTN2/BRINP1 locus at 9q33.1-33.2 is associated with major psychiatric disorders in a large pedigree from Southern Spain. | Pol-Fuster J et al. | — | 2021 | → |
| The functional polymorphisms linked with interleukin-1β gene expression are associated with bipolar disorder. | Pu X et al. | — | 2021 | → |
| The Genetic Architecture of Depression in Individuals of East Asian Ancestry: A Genome-Wide Association Study. | Giannakopoulou O et al. | — | 2021 | → |
| The genetic architecture of human complex phenotypes is modulated by linkage disequilibrium and heterozygosity. | Holland D et al. | — | 2021 | → |
| The genetic architecture of the human thalamus and its overlap with ten common brain disorders. | Elvsåshagen T et al. | — | 2021 | → |
| The genetic basis of major depression. | Kendall KM et al. | — | 2021 | → |
| The impact of parenting a child with serious mental illness: Accounting for the parent's genetic vulnerability to mental illness. | Greenberg J et al. | — | 2021 | → |
| The overlap of genetic susceptibility to schizophrenia and cardiometabolic disease can be used to identify metabolically different groups of individuals. | Strawbridge RJ et al. | — | 2021 | → |
| The patterns of family genetic risk scores for eleven major psychiatric and substance use disorders in a Swedish national sample. | Kendler KS et al. | — | 2021 | → |
| The predictive capacity of psychiatric and psychological polygenic risk scores for distinguishing cases in a child and adolescent psychiatric sample from controls. | Jansen AG et al. | — | 2021 | → |
| The Role of Genetics in Bipolar Disorder. | Fabbri C | — | 2021 | → |
| The Role of Mitonuclear Incompatibility in Bipolar Disorder Susceptibility and Resilience Against Environmental Stressors. | Gonzalez S | — | 2021 | → |
| The Role of the UPR Pathway in the Pathophysiology and Treatment of Bipolar Disorder. | Suliman M et al. | — | 2021 | → |
| The shared genetic architecture of schizophrenia, bipolar disorder and lifespan. | Muntané G et al. | — | 2021 | → |
| Thyroid Function and Mood Disorders: A Mendelian Randomization Study. | Kuś A et al. | — | 2021 | → |
| Transcription factor POU3F2 regulates TRIM8 expression contributing to cellular functions implicated in schizophrenia. | Ding C et al. | — | 2021 | → |
| Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex. | Maynard KR et al. | — | 2021 | → |
| Transcriptome-wide association study identifies new susceptibility genes and pathways for depression. | Li X et al. | — | 2021 | → |
| Transcriptome-Wide Association Study Provides Insights Into the Genetic Component of Gene Expression in Anxiety. | Su X et al. | — | 2021 | → |
| Transcriptome-wide association study reveals two genes that influence mismatch negativity. | Bhat A et al. | — | 2021 | → |
| Transcriptome-Wide Identification of G-to-A RNA Editing in Chronic Social Defeat Stress Mouse Models. | Tao J et al. | — | 2021 | → |
| Translating polygenic risk scores for clinical use by estimating the confidence bounds of risk prediction. | Sun J et al. | — | 2021 | → |
| Translational genomics and beyond in bipolar disorder. | Zhang C et al. | — | 2021 | → |
| Understanding the genetic contribution of the human leukocyte antigen system to common major psychiatric disorders in a world pandemic context. | Tamouza R et al. | — | 2021 | → |
| Unveiling the Pathogenesis of Psychiatric Disorders Using Network Models. | Zuo Y et al. | — | 2021 | → |
| Using iPSC Models to Understand the Role of Estrogen in Neuron-Glia Interactions in Schizophrenia and Bipolar Disorder. | Reis de Assis D et al. | — | 2021 | → |
| Using Mendelian randomization analysis to better understand the relationship between mental health and substance use: a systematic review. | Treur JL et al. | — | 2021 | → |
| Weighted Gene Coexpression Network Analysis Reveals Essential Genes and Pathways in Bipolar Disorder. | Zhang ZQ et al. | — | 2021 | → |
| Adolescent residential mobility, genetic liability and risk of schizophrenia, bipolar disorder and major depression. | Paksarian D et al. | — | 2020 | → |
| Allele-specific open chromatin in human iPSC neurons elucidates functional disease variants. | Zhang S et al. | — | 2020 | → |
| A meta-review of "lifestyle psychiatry": the role of exercise, smoking, diet and sleep in the prevention and treatment of mental disorders. | Firth J et al. | — | 2020 | → |
| An integrated Asian human SNV and indel benchmark established using multiple sequencing methods. | Huang C et al. | — | 2020 | → |
| A principal component approach to improve association testing with polygenic risk scores. | Coombes BJ et al. | — | 2020 | → |
| Assessing the Causal Effects of Human Serum Metabolites on 5 Major Psychiatric Disorders. | Yang J et al. | — | 2020 | → |
| Assessment of Genetic Association Between Parkinson Disease and Bipolar Disorder. | Bandres-Ciga S et al. | — | 2020 | → |
| Association Analysis Between Common Variants of the <i>TRPM1</i> Gene and Three Mental Disorders in the Han Chinese Population. | Ma C et al. | — | 2020 | → |
| Associations of cigarette smoking with psychiatric disorders: evidence from a two-sample Mendelian randomization study. | Yuan S et al. | — | 2020 | → |
| Attitudes on pharmacogenetic testing in psychiatric patients with treatment-resistant depression. | McCarthy MJ et al. | — | 2020 | → |
| Autism spectrum disorder genomics: The progress and potential of genomic technologies. | Nà Ghrálaigh F et al. | — | 2020 | → |
| Beyond SNP heritability: Polygenicity and discoverability of phenotypes estimated with a univariate Gaussian mixture model. | Holland D et al. | — | 2020 | → |
| Bipolar Disorder. | Carvalho AF et al. | — | 2020 | → |
| Bipolar disorders. | McIntyre RS et al. | — | 2020 | → |
| Cell-type-specific 3D epigenomes in the developing human cortex. | Song M et al. | — | 2020 | → |
| Clock gene polygenic risk score and seasonality in major depressive disorder and bipolar disorder. | Ferrer A et al. | — | 2020 | → |
| Common genetic risk variants identified in the SPARK cohort support DDHD2 as a candidate risk gene for autism. | Matoba N et al. | — | 2020 | → |
| Common schizophrenia risk variants are enriched in open chromatin regions of human glutamatergic neurons. | Hauberg ME et al. | — | 2020 | → |
| Delineating the Shared Genetics Across the Mood Disorders Spectrum. | Warrier V | — | 2020 | → |
| Determinants of Base Editing Outcomes from Target Library Analysis and Machine Learning. | Arbab M et al. | — | 2020 | → |
| Differences in course of illness between patients with bipolar II disorder with and without epileptiform discharges or other sharp activity on electroencephalograms: a cross-sectional study. | Drange OK et al. | — | 2020 | → |
| Dissecting clinical heterogeneity of bipolar disorder using multiple polygenic risk scores. | Coombes BJ et al. | — | 2020 | → |
| Do Current Measures of Polygenic Risk for Mental Disorders Contribute to Population Variance in Mental Health? | Marsman A et al. | — | 2020 | → |
| Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits. | Quach BC et al. | — | 2020 | → |
| Exploring the Relationship Between Psychiatric Traits and the Risk of Mouth Ulcers Using Bi-Directional Mendelian Randomization. | Wang K et al. | — | 2020 | → |
| Fluctuations of consciousness, mood, and science: The interhemispheric switch and sticky switch models two decades on. | Miller SM | — | 2020 | → |
| Functional genomics links genetic origins to pathophysiology in neurodegenerative and neuropsychiatric disease. | Wamsley B et al. | — | 2020 | → |
| GADL1 is a multifunctional decarboxylase with tissue-specific roles in β-alanine and carnosine production. | Mahootchi E et al. | — | 2020 | → |
| Gene-set Enrichment with Mathematical Biology (GEMB). | Cochran AL et al. | — | 2020 | → |
| Genetic Associations Between Childhood Psychopathology and Adult Depression and Associated Traits in 42 998 Individuals: A Meta-analysis. | Akingbuwa WA et al. | — | 2020 | → |
| Genetic colocalization atlas points to common regulatory sites and genes for hematopoietic traits and hematopoietic contributions to disease phenotypes. | Thom CS et al. | — | 2020 | → |
| Genetic differences between bipolar disorder subtypes: A systematic review focused in bipolar disorder type II. | Almeida HS et al. | — | 2020 | → |
| Genetic liability in individuals at ultra-high risk of psychosis: A comparison study of 9 psychiatric traits. | Lim K et al. | — | 2020 | → |
| Genetics and major depressive disorder: clinical implications for disease risk, prognosis and treatment. | Fabbri C et al. | — | 2020 | → |
| Genome-wide association study and polygenic risk score analysis of esketamine treatment response. | Li QS et al. | — | 2020 | → |
| Genome-wide Association Study of Creativity Reveals Genetic Overlap With Psychiatric Disorders, Risk Tolerance, and Risky Behaviors. | Li H et al. | — | 2020 | → |
| Genome-Wide Association Study of Suicide Death and Polygenic Prediction of Clinical Antecedents. | Docherty AR et al. | — | 2020 | → |
| Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits. | Zhou H et al. | — | 2020 | → |
| Genomic analysis of the natural history of attention-deficit/hyperactivity disorder using Neanderthal and ancient Homo sapiens samples. | Esteller-Cucala P et al. | — | 2020 | → |
| How to prevent the malignant progression of bipolar disorder. | Post RM | — | 2020 | → |
| Identification of de novo mutations in prenatal neurodevelopment-associated genes in schizophrenia in two Han Chinese patient-sibling family-based cohorts. | Jiang S et al. | — | 2020 | → |
| Impact of schizophrenia genetic liability on the association between schizophrenia and physical illness: data-linkage study. | Kendall KM et al. | — | 2020 | → |
| Integration of CRISPR-engineering and hiPSC-based models of psychiatric genomics. | Matos MR et al. | — | 2020 | → |
| Interaction between adverse childhood experiences and polygenic risk in patients with bipolar disorder. | Park YM et al. | — | 2020 | → |
| Involvement of the 14-3-3 Gene Family in Autism Spectrum Disorder and Schizophrenia: Genetics, Transcriptomics and Functional Analyses. | Torrico B et al. | — | 2020 | → |
| Lithium and the Interplay Between Telomeres and Mitochondria in Bipolar Disorder. | Lundberg M et al. | — | 2020 | → |
| Methyl-CpG-binding protein 2 mediates overlapping mechanisms across brain disorders. | Bach S et al. | — | 2020 | → |
| MicroRNA Alterations in Induced Pluripotent Stem Cell-Derived Neurons from Bipolar Disorder Patients: Pathways Involved in Neuronal Differentiation, Axon Guidance, and Plasticity. | Bame M et al. | — | 2020 | → |
| Molecular Genetic Risk for Psychosis Is Associated With Psychosis Risk Symptoms in a Population-Based UK Cohort: Findings From Generation Scotland. | Docherty AR et al. | — | 2020 | → |
| Mood-Stabilizing Antiepileptic Treatment Response in Bipolar Disorder: A Genome-Wide Association Study. | Ho AM et al. | — | 2020 | → |
| Multivariable G-E interplay in the prediction of educational achievement. | Allegrini AG et al. | — | 2020 | → |
| Network-based approach highlighting interplay among anti-hypertensives: target coding-genes: diseases. | Sharma R | — | 2020 | → |
| Neurobiology of bipolar disorders: a review of genetic components, signaling pathways, biochemical changes, and neuroimaging findings. | Scaini G et al. | — | 2020 | → |
| Neuronal α<sub>2</sub>δ proteins and brain disorders. | Ablinger C et al. | — | 2020 | → |
| Ntrk1 mutation co-segregating with bipolar disorder and inherited kidney disease in a multiplex family causes defects in neuronal growth and depression-like behavior in mice. | Nakajima K et al. | — | 2020 | → |
| Opportunities and limitations of genetically modified nonhuman primate models for neuroscience research. | Feng G et al. | — | 2020 | → |
| Phenotype-specific differences in polygenicity and effect size distribution across functional annotation categories revealed by AI-MiXeR. | Shadrin AA et al. | — | 2020 | → |
| Plasma microRNA Array Analysis Identifies Overexpressed miR-19b-3p as a Biomarker of Bipolar Depression Distinguishing From Unipolar Depression. | Chen Y et al. | — | 2020 | → |
| Polygenic prediction of the risk of perinatal depressive symptoms. | Rantalainen V et al. | — | 2020 | → |
| Polygenic risk for anxiety influences anxiety comorbidity and suicidal behavior in bipolar disorder. | Lopes FL et al. | — | 2020 | → |
| Polygenic risk scores and their potential clinical use in psychiatry: are we there yet? | Fries GR | — | 2020 | → |
| Reduced Brd1 expression leads to reversible depression-like behaviors and gene-expression changes in female mice. | Rajkumar AP et al. | — | 2020 | → |
| Risk Stratification for Bipolar Disorder Using Polygenic Risk Scores Among Young High-Risk Adults. | Biere S et al. | — | 2020 | → |
| Seasonal effects on bipolar disorder: A closer look. | Rosenthal SJ et al. | — | 2020 | → |
| Shared polygenic risk for ADHD, executive dysfunction and other psychiatric disorders. | Chang S et al. | — | 2020 | → |
| Single-Cell Analysis of the Gene Expression Effects of Developmental Lead (Pb) Exposure on the Mouse Hippocampus. | Bakulski KM et al. | — | 2020 | → |
| Telomere length and human hippocampal neurogenesis. | Palmos AB et al. | — | 2020 | → |
| Testing structural models of psychopathology at the genomic level. | Waldman ID et al. | — | 2020 | → |
| The 2020 Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders: Major depression summary. | Malhi GS et al. | — | 2020 | → |
| The biology of aggressive behavior in bipolar disorder: A systematic review. | Fico G et al. | — | 2020 | → |
| The Discovery of Clinically Applicable Biomarkers for Bipolar Disorder: A Review of Candidate and Proteomic Approaches. | Muneer A | — | 2020 | → |
| The effects of polygenic risk for psychiatric disorders and smoking behaviour on psychotic experiences in UK Biobank. | GarcÃa-González J et al. | — | 2020 | → |
| The genetic architecture of human brainstem structures and their involvement in common brain disorders. | Elvsåshagen T et al. | — | 2020 | → |
| The Impact of Childhood Trauma on Developing Bipolar Disorder: Current Understanding and Ensuring Continued Progress. | Quidé Y et al. | — | 2020 | → |
| The peripartum human brain: Current understanding and future perspectives. | Sacher J et al. | — | 2020 | → |
| The polygenic architecture of schizophrenia - rethinking pathogenesis and nosology. | Smeland OB et al. | — | 2020 | → |
| The search for personalized antidepressant treatments: what have we learned and where are we going. | Serretti A et al. | — | 2020 | → |
| Translating big data to better treatment in bipolar disorder - a manifesto for coordinated action. | Manchia M et al. | — | 2020 | → |
| TWAS pathway method greatly enhances the number of leads for uncovering the molecular underpinnings of psychiatric disorders. | Chatzinakos C et al. | — | 2020 | → |
| Validity and utility of Hierarchical Taxonomy of Psychopathology (HiTOP): I. Psychosis superspectrum. | Kotov R et al. | — | 2020 | → |