Detailed cohort descriptions, information about cohort-level genotyping and imputation procedures, cohort-level measures, and quality-control filters are shown in Supplementary Tables 2–6. Supplementary Table 7 reports association results from the following four meta-analyses: the primary subjective well-being analysis, the life satisfaction analysis, the positive affect analysis, and the post hoc subjective well-being analysis. For each phenotype, we provide association results for the set of approximately independent SNPs that attained a p-value smaller than 10−5. We identify these SNP using the same clumping algorithm as for the lead SNPs, but with the p-value threshold set at 10−5 instead of genome-wide significance.