had a lower family history density of alcohol problems than a comparison group of middle-aged long-term abstinent alcoholics (Di Sclafani et al., 2008). A positive family history of addiction problems is associated with smaller regional brain volumes (Benegal et al., 2007), electrophysiological abnormalities (Begleiter et al., 1984; Porjesz et al., 1998), and disinhibitory personality traits associated with an externalizing diathesis (Benegal et al., 2007; Krueger et al., 2009).
