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Chunk #17 — 3. RESULTS — 3.3 Timing of drinking during pregnancy

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Maternal alcohol consumption producing fetal alcohol spectrum disorders (FASD): quantity, frequency, and timing of drinking.
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Timing of drinking by trimester (Table 1) demonstrates significant differences for DDD across maternal groups. First trimester means range from 6.8 for mothers of FAS to 3.8 for the mothers of exposed, normal children. On the other hand, estimated peak BAC’s for the drinking in each group do not differ significantly by trimester, indicating that peak BAC is not a good measure of risk for FASD in this population where binge drinking is the normative style and because it does not capture frequency of drinking. Figure 1 illustrates that DDD drop for each group with each trimester; but error bars (noting standard error) indicate much individual variation. Post hoc analyses illustrate significant differences of DDD at all three trimesters between the FAS, PFAS, and ARND groups compared with unexposed controls, and significant differences: for the first trimester between exposed and unexposed controls and for both the second and third trimesters between the FAS group and unexposed controls.