to produce exciting insights into possible prevention and intervention paradigms through independent studies (e.g., References 60, 61, 62, 63). There are numerous priority areas in the field of alcohol research where COGA continues to have scientific impact. For example, while most AUD research, including in our own prospective cohort, has focused on the onset of AUD and its persistence and abatement during middle adulthood, far less is known about the medical and psychosocial sequelae of AUD in later life. Recent epidemiological surveys call attention to notable increases in heavy drinking in older adults, 2 , 80 , 81 and quite likely, the factors conferring risk and resilience in this epoch of life might be distinct. In addition to understanding why an individual might continue to engage in problematic drinking as they age, the consequences of AUD—on neurocognitive markers, risk for cardiometabolic disease, liver health, accidents and importantly, shortened life expectancy—is one scientific domain in which COGA's longitudinally characterized, family‐based and aging cohort may be of utility. At the other end of the lifecourse, as offspring of COGA members attain child‐bearing age, opportunities to address questions related to intergenerational transmission of behavioral, genetic/epigenetic and brain‐related liability arise. 7 While current studies
