α (8–12 Hz) oscillations and the default mode network (DMN) both dominate the resting-state brain activity and are found to be closely related. In addition, aberrant α and DMN activities are both implicated in the pathophysiology of posttraumatic stress disorder (PTSD). Linking α and DMN aberrations in PTSD, our high-density electroencephalogram (hdEEG) source analysis reveals that PTSD is associated with α power deficits across the DMN and visual cortex (VC) and deficient α-frequency connectivity from the VC to the DMN. That this visual-cortex-DMN α dysrhythmia further underpins hypervigilance symptoms in PTSD highlights a temporal-spatial network pathology, promoting network-based neural oscillatory interventions.
