The major findings of this study are that(a) adolescent male P rats will consume 8–10 g ethanol/kg body wt/day with 3 daily binge-like drinking episodes; (b) significant changes in gene expression were found in both the CeA and Acb-sh, with 26 genes in common between the two regions; (c) there was little overlap between the 2 regions in the GO and KEGG pathways altered by adolescent binge-like drinking; and (d) adolescent alcohol drinking produced changes in several intracellular signaling pathways in both regions.
