To test the secondary aim, a series of models tested the effects of Severity (i.e., factor score), Alcohol, Time, and the Alcohol × Severity interaction on the dependent variables of interest. Results revealed a main effect of Severity on Sedation (β = 6.65, SE = 2.40, t = 2.77, p< .01) and Craving (β = 0.58, SE = 0.29, t = 2.01, p< .05) across both infusions. However, there was no Alcohol × Severity interaction for either Sedation (β = −1.02, SE = 1.16, t = −0.88, p = .38) or Craving (β = 0.02, SE = 0.13, t = 0.13, p = .90). There were no main effects of Severity or Alcohol × Severity interactions on measures of the hedonic effects of alcohol, namely stimulation, vigor, and positive mood (ps> .10). Together, these results suggest that individuals at higher levels of alcoholism severity reported more sedation and alcohol craving during the infusions, yet these effects were not unique to the alcohol condition.
