To carry out tissue-specific eQTL enrichment analysis, we used 44 tissue types with at least 70 samples available from GTex32 in addition to seven kidney eQTLs33. We used 367 sentinel variants from previously-identified SNPs and the three discovery stages presented here with MAF>0.001 and in eQTL databases. Next, 100 sets of 367 random pseudo-sentinel variants were selected matching the MAF to the original 367 (within ±0.5%). Within each set, the selection was done without replacement; the match for each variant was selected one-at-a-time, and selection of the subsequent variant excluded all previously-selected variants, as well as all variants within ±0.5 Mb of all previously-selected variants.
