We next conducted meta-analyses of the EUR MVP and PGC PTSD case-control GWAS13 (Fig. 1 (bottom) and Supplementary Table 4a). The EUR meta-analysis yielded four distinct GWS loci, two of which were nearest to genes found GWS in the MVP case-control analysis (MAD1L1 and METTL15) although with different lead SNPs: one new SNP (nearest to LOC645949) and one lead SNP closest to PACRG, a gene linked in a head-to-head arrangement and co-regulated with PARK2 – a gene found GWS in PGC. There were no GWS SNPs for the AFR MVP/PGC PTSD meta-analysis, but two SNPs were GWS in the trans-ancestral meta-analysis with lead SNPs closest to PARK2 and MAD1L1, respectively (Supplementary Table 4b,c).
